ChemicalBook > CAS DataBase List > Thalidomide-NH-PEG2-C2-NH2 hydrochloride
Thalidomide-NH-PEG2-C2-NH2 hydrochloride
- Product Name
- Thalidomide-NH-PEG2-C2-NH2 hydrochloride
- CAS No.
- 2245697-87-2
- Chemical Name
- Thalidomide-NH-PEG2-C2-NH2 hydrochloride
- Synonyms
- -PEG2-amine;Poma-PEG2-NH2·HCl;Pomalidomide 4’Pomalidomide 4'-PEG2-amine;Thalidomide-NH-PEG2-NH2 HCl;Thalidomide-PEG2-C2-NH2 HCl;Pomalidomide 4'-PEG2-amine, HCl salt;Pomalidomide 4'-PEG2-amine, HCl salt;Thalidomide-PEG2-C2-NH2 hydrochloride;4-(H2N-PEG2-CH2CH2NH)-Thalidomide HCl
- CBNumber
- CB08054836
- Molecular Formula
- C19H25ClN4O6
- Formula Weight
- 440.88
- MOL File
- 2245697-87-2.mol
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Thalidomide-NH-PEG2-C2-NH2 hydrochloride Property
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- color
- Light yellow to green yellow
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Thalidomide-NH-PEG2-C2-NH2 hydrochloride Chemical Properties,Usage,Production
Uses
Thalidomide-PEG2-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1].
IC 50
Cereblon
storage
Store at -20°C
References
[1] Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163. DOI:10.1021/acs.jmedchem.9b00919
Thalidomide-NH-PEG2-C2-NH2 hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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Thalidomide-NH-PEG2-C2-NH2 hydrochloride Suppliers
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View Lastest Price from Thalidomide-NH-PEG2-C2-NH2 hydrochloride manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- Pomalidomide-NH-PEG2-amine hydrochloride 2245697-87-2
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >99.00%
- Supply Ability
- 1g
- Release date
- 2024-04-01
2245697-87-2, Thalidomide-NH-PEG2-C2-NH2 hydrochlorideRelated Search:
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E3 ligase Ligand-Linker Conjugates 15
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