ChemicalBook > CAS DataBase List > Thalidomide-NH-PEG2-C2-NH2 hydrochloride

Thalidomide-NH-PEG2-C2-NH2 hydrochloride

Product Name: Thalidomide-NH-PEG2-C2-NH2 hydrochloride
CAS No.: 2245697-87-2
Chemical Name: Thalidomide-NH-PEG2-C2-NH2 hydrochloride
Synonyms: -PEG2-amine;Poma-PEG2-NH2·HCl;Pomalidomide 4’Pomalidomide 4'-PEG2-amine;Thalidomide-NH-PEG2-NH2 HCl;Thalidomide-PEG2-C2-NH2 HCl;Pomalidomide 4'-PEG2-amine, HCl salt;Pomalidomide 4'-PEG2-amine, HCl salt;Thalidomide-PEG2-C2-NH2 hydrochloride;4-(H2N-PEG2-CH2CH2NH)-Thalidomide HCl
CBNumber: CB08054836
Molecular Formula: C19H25ClN4O6
Formula Weight: 440.88
MOL File: 2245697-87-2.mol

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Thalidomide-NH-PEG2-C2-NH2 hydrochloride Property

storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Solid
color: Light yellow to green yellow

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Hazard and Precautionary Statements (GHS)

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Thalidomide-NH-PEG2-C2-NH2 hydrochloride Chemical Properties,Usage,Production

Uses

Thalidomide-PEG2-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1].

IC 50

Cereblon

storage

Store at -20°C

References

[1] Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163. DOI:10.1021/acs.jmedchem.9b00919

Thalidomide-NH-PEG2-C2-NH2 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Thalidomide-NH-PEG2-C2-NH2 hydrochloride manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Pomalidomide-NH-PEG2-amine hydrochloride 2245697-87-2
Price: US $0.00/g
Min. Order: 1g
Purity: >99.00%
Supply Ability: 1g
Release date: 2024-04-01

2245697-87-2, Thalidomide-NH-PEG2-C2-NH2 hydrochlorideRelated Search:

Thalidomide-O-amido-C2-NH2 4-((2-(2-(2-aminoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione 2-(2,6-dioxopiperidin-3-yl)-4-(prop-2-yn-1-yloxy)isoindoline-1,3-dione -alkylC5-amine 4-[(6-Aminohexyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl E3 ligase Ligand-Linker Conjugates 15 Thalidomide-O-amido-C2-NH2 Thalidomide-NH-C4-NH-Boc Thalidomide-NH-C6-NH2 TFA Thalidomide-NH-C4-NH2 TFA Thalidomide-NH-PEG2-C2-NH2 (TFA)

Thalidomide-NH-PEG2-C2-NH2 hydrochloride

Pomalidomide 4&rsquo

-PEG2-amine

Pomalidomide-NH-PEG2-amine hydrochloride

Thalidomide-NH-PEG2-NH2 HCl

Thalidomide-PEG2-C2-NH2 hydrochloride

Pomalidomide 4'-PEG2-amine hydrochloride

1H-Isoindole-1,3(2H)-dione, 4-[[2-[2-(2-aminoethoxy)ethoxy]ethyl]amino]-2-(2,6-dioxo-3-piperidinyl), 4-[[2-[2-(2-Aminoethoxy)ethoxy]ethyl]amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

Poma-PEG2-NH2·HCl

Pomalidomide 4'-PEG2-amine, HCl salt

Pomalidomide 4'-PEG2-amine

Thalidomide-PEG2-C2-NH2 HCl

Pomalidomide-PEG2-C2-NH2 hydrochloride

Pomalidomide 4'-PEG2-amine, HCl salt

4-(H2N-PEG2-CH2CH2NH)-Thalidomide HCl

2245697-87-2