-alkylC5-amine

Product Name: -alkylC5-amine
CAS No.: 2375194-03-7
Chemical Name: -alkylC5-amine
Synonyms: -alkylC5-amine;Poma-C5-NH2·HCl;Thalidomide-NH-C5-NH2 HC;Thalidomide-NH-C5-NH2 HCl;Thalidomide-NH-C5-NH2, HCl salt;Pomalidomide-C5-NH2 hydrochloride;Thalidomide-NH-C5-NH2 hydrochloride;Pomalidomide 4'-alkylC5-amine hydrochloride;4-(5-aminopentylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;4-((5-Aminopentyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride
CBNumber: CB78202915
Molecular Formula: C18H23ClN4O4
Formula Weight: 394.86
MOL File: 2375194-03-7.mol

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-alkylC5-amine Property

storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Solid
color: Light yellow to green yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H312Harmful in contact with skin

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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-alkylC5-amine Chemical Properties,Usage,Production

Uses

Thalidomide-NH-C5-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].

IC 50

Cereblon

storage

Store at -20°C

References

[1] Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine.Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11. DOI:10.3389/fcell.2021.629326
[2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277

-alkylC5-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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-alkylC5-amine Suppliers

China 36 United States 2 Global 38

Shanghai GaoDao Pharmaceutical Co., Ltd.

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Shanghai YuanYe Biotechnology Co., Ltd.

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Xi'an Confluore Biological Technology Co., Ltd.

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Jiangsu aikang biomedical research and development co., LTD

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Jilin Province Woda Biotechnology Co., Ltd.

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Zhengzhou Alfa Chemical Co.,Ltd

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View Lastest Price from -alkylC5-amine manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Pomalidomide-C5-NH2 hydrochloride 2375194-03-7
Price: US $0.00/g
Min. Order: 1g
Purity: >99.00%
Supply Ability: 1g
Release date: 2024-04-01

2375194-03-7, -alkylC5-amineRelated Search:

Thalidomide-O-amido-C2-NH2 4-((2-(2-(2-aminoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione 2-(2,6-dioxopiperidin-3-yl)-4-(prop-2-yn-1-yloxy)isoindoline-1,3-dione Thalidomide-NH-C6-NH2 TFA 4-[(6-Aminohexyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl E3 ligase Ligand-Linker Conjugates 15 Thalidomide-O-amido-C2-NH2 Thalidomide-NH-PEG2-C2-NH2 hydrochloride Thalidomide-NH-PEG2-C2-NH2 (TFA) Thalidomide-NH-C4-NH-Boc Undecanoic acid, 11-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Thalidomide-NH-C4-NH2 TFA 4-[(4-Aminobutyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Pomalidomide-C6-NH2?hydrochloride 1H-Isoindole-1,3(2H)-dione, 4-[(2-aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1) β-Alanine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- 4-((4-azidobutyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

-alkylC5-amine

Thalidomide-NH-C5-NH2 hydrochloride

Pomalidomide-C5-NH2 hydrochloride

4-((5-Aminopentyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride

Poma-C5-NH2·HCl

Pomalidomide 4'-alkylC5-amine hydrochloride

Thalidomide-NH-C5-NH2, HCl salt

4-(5-aminopentylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione

Thalidomide-NH-C5-NH2 HCl

1H-Isoindole-1,3(2H)-dione, 4-[(5-aminopentyl)amino]-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1)

Thalidomide-NH-C5-NH2 HC

2375194-03-7