ChemicalBook > CAS DataBase List > -alkylC5-amine
-alkylC5-amine
- Product Name
- -alkylC5-amine
- CAS No.
- 2375194-03-7
- Chemical Name
- -alkylC5-amine
- Synonyms
- -alkylC5-amine;Poma-C5-NH2·HCl;Thalidomide-NH-C5-NH2 HCl;Thalidomide-NH-C5-NH2, HCl salt;Pomalidomide-C5-NH2 hydrochloride;Thalidomide-NH-C5-NH2 hydrochloride;Pomalidomide 4'-alkylC5-amine hydrochloride;4-(5-aminopentylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;4-((5-Aminopentyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride
- CBNumber
- CB78202915
- Molecular Formula
- C18H23ClN4O4
- Formula Weight
- 394.86
- MOL File
- 2375194-03-7.mol
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-alkylC5-amine Property
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- color
- Light yellow to green yellow
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-alkylC5-amine Chemical Properties,Usage,Production
Uses
Thalidomide-NH-C5-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
IC 50
Cereblon
storage
Store at -20°C
References
[1] Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine.?Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11. DOI:10.3389/fcell.2021.629326
[2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277
-alkylC5-amine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from -alkylC5-amine manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- Pomalidomide-C5-NH2 hydrochloride 2375194-03-7
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >99.00%
- Supply Ability
- 1g
- Release date
- 2024-04-01
2375194-03-7, -alkylC5-amineRelated Search:
Thalidomide-O-amido-C2-NH2
4-((2-(2-(2-aminoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
2-(2,6-dioxopiperidin-3-yl)-4-(prop-2-yn-1-yloxy)isoindoline-1,3-dione
Thalidomide-NH-C6-NH2 TFA
4-[(6-Aminohexyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl
E3 ligase Ligand-Linker Conjugates 15
Thalidomide-O-amido-C2-NH2
Thalidomide-NH-PEG2-C2-NH2 hydrochloride
Thalidomide-NH-PEG2-C2-NH2 (TFA)
Thalidomide-NH-C4-NH-Boc
Undecanoic acid, 11-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-
Thalidomide-NH-C4-NH2 TFA
4-[(4-Aminobutyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl
Pomalidomide-C6-NH2?hydrochloride
1H-Isoindole-1,3(2H)-dione, 4-[(2-aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1)
β-Alanine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-
4-((4-azidobutyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione