ChemicalBook > CAS DataBase List > β-Alanine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-

β-Alanine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-

Product Name
β-Alanine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
CAS No.
2225940-46-3
Chemical Name
β-Alanine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
Synonyms
Poma-C2-COOH;Pomalidomide-C2-acid;Thalidomide-NH-C2-COOH;Thalidomide-4-NH-C2-COOH;PomalidomideC2acid,Pomalidomide-C-2-acid,Pomalidomide C2 acid;N-[2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl]-b-alanine;3-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]propanoic acid;3-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)propanoic acid;N-[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-β-alanine;β-Alanine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
CBNumber
CB38124660
Molecular Formula
C16H15N3O6
Formula Weight
345.31
MOL File
2225940-46-3.mol
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β-Alanine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- Property

Boiling point:
708.5±60.0 °C(Predicted)
Density 
1.578±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
form 
Solid
pka
4.42±0.10(Predicted)
color 
Off-white to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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β-Alanine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- Chemical Properties,Usage,Production

Uses

Pomalidomide-C2-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1].

IC 50

Cereblon

References

[1] Md Kabir, et al. Discovery and Characterization of a Novel Cereblon-Recruiting PRC1 Bridged PROTAC Degrader. J Med Chem. 2024 Apr 25;67(8):6880-6892. DOI:10.1021/acs.jmedchem.4c00538

β-Alanine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- Preparation Products And Raw materials

Raw materials

Preparation Products

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β-Alanine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- Suppliers

China 39 United States 3 Global 42
Daicel Chiral Technologies (China)CO.,LTD
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2225940-46-3, β-Alanine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-Related Search:

Thalidomide-NH-PEG2-C2-NH2 (TFA) 5-[[2-(2-aminoethoxy)ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-1H-Isoindole-1,3(2H)-dione, Pentanoic acid, 5-[[2-(2,6-dioxo-3-piperidinyl)- 2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]amino]- 1H-Isoindole-1,3(2H)-dione, 4-(3-aminopropoxy)-2-(2,6-dioxo-3-piperidinyl)- 5-[(8-aminobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-Isoindole-1,3(2H)-dione, 1H-Isoindole-1,3(2H)-dione, 4-(2-aminoethoxy)-2-(2,6-dioxo-3-piperidinyl)- 5-[(5-aminobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-Isoindole-1,3(2H)-dione, 5-[(7-aminobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-Isoindole-1,3(2H)-dione, Thalidomide-O-C10-NH2 1H-Isoindole-1,3(2H)-dione, 5-[(2-aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)- 3-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)amino)propanoic acid 5-[(3-aminopropyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-Isoindole-1,3(2H)-dione, Thalidomide-O-C5-NH2 Thalidomide-4-O-C8-NH2 5-[(6-aminobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-Isoindole-1,3(2H)-dione, POMALIDOMIDE-C9-CO2H 4-[(6-Aminohexyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Thalidomide-NH-C6-NH2 TFA

  • β-Alanine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
  • N-[2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl]-b-alanine
  • 3-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)propanoic acid
  • 3-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]propanoic acid
  • Pomalidomide-C2-acid
  • PomalidomideC2acid,Pomalidomide-C-2-acid,Pomalidomide C2 acid
  • Thalidomide-NH-C2-COOH
  • Thalidomide-4-NH-C2-COOH
  • Poma-C2-COOH
  • N-[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-β-alanine
  • 2225940-46-3