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Thalidomide-O-C10-NH2

Product Name
Thalidomide-O-C10-NH2
CAS No.
1957236-08-6
Chemical Name
Thalidomide-O-C10-NH2
Synonyms
Thalidomide-O-C10-NH2;Thalidomide-4-O-C10-NH2;4-[(10-Aminodecyl)oxy]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione;1H-Isoindole-1,3(2H)-dione, 4-[(10-aminodecyl)oxy]-2-(2,6-dioxo-3-piperidinyl)-;4-[(10-aminodecyl)oxy]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione
CBNumber
CB48381152
Molecular Formula
C23H31N3O5
Formula Weight
429.51
MOL File
1957236-08-6.mol
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Thalidomide-O-C10-NH2 Property

Boiling point:
644.1±50.0 °C(Predicted)
Density 
1.234±0.06 g/cm3(Predicted)
pka
10.70±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)

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Thalidomide-O-C10-NH2 Chemical Properties,Usage,Production

Uses

Thalidomide-4-O-C10-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].

IC 50

Cereblon

References

[1] Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine.?Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11. DOI:10.3389/fcell.2021.629326
[2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1008. DOI:10.1016/j.cell.2020.07.024

Thalidomide-O-C10-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

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Thalidomide-O-C10-NH2 Suppliers

China 3 Global 3
Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
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+86-21-50462321
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han_yajun@dctc.daicel.com
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China
ProdList
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Jilin Province Woda Biotechnology Co., Ltd.
Tel
13504435624
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1927928688@qq.com
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China
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1615
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ShenZhen Trendseen Biological Technology Co.,Ltd.
Tel
13417589054;
Email
trendseenbio@gmail.com
Country
China
ProdList
9069
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58

1957236-08-6, Thalidomide-O-C10-NH2Related Search:

Thalidomide-4-O-C6-NH2 hydrochloride Thalidomide-O-C5-acid Thalidomide-O-C6-NH2 Thalidomide-linker 9 Thalidomide-linker 6 Thalidomide-O-C6-NH2 TFA Pentanoic acid, 5-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- Propanoic acid, 3-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- 1H-Isoindole-1,3(2H)-dione, 4-[(7-aminoheptyl)oxy]-2-(2,6-dioxo-3-piperidinyl)- Thalidomide-O-C3-acid Thalidomide-O-C6-acid Thalidomide-NH-PEG2-C2-NH2 (TFA) 5-[[2-(2-aminoethoxy)ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-1H-Isoindole-1,3(2H)-dione, Pentanoic acid, 5-[[2-(2,6-dioxo-3-piperidinyl)- 2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]amino]- 1H-Isoindole-1,3(2H)-dione, 4-(3-aminopropoxy)-2-(2,6-dioxo-3-piperidinyl)- 5-[(8-aminobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-Isoindole-1,3(2H)-dione, 1H-Isoindole-1,3(2H)-dione, 4-(2-aminoethoxy)-2-(2,6-dioxo-3-piperidinyl)- β-Alanine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-

  • 1H-Isoindole-1,3(2H)-dione, 4-[(10-aminodecyl)oxy]-2-(2,6-dioxo-3-piperidinyl)-
  • Thalidomide-O-C10-NH2
  • Thalidomide-4-O-C10-NH2
  • 4-[(10-Aminodecyl)oxy]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione
  • 4-[(10-aminodecyl)oxy]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione
  • 1957236-08-6