ChemicalBook > CAS DataBase List > 2,4-Thiazolidinedione

2,4-Thiazolidinedione

Product Name
2,4-Thiazolidinedione
CAS No.
2295-31-0
Chemical Name
2,4-Thiazolidinedione
Synonyms
THIAZOLIDINE-2,4-DIONE;TZD;Thiazolidinedione;2,4-Thiazolidindione;U 25560;idinedione;usafek-5496;2,4-ThiazoL;USAF ek-5496;AURORA 23272
CBNumber
CB6675365
Molecular Formula
C3H3NO2S
Formula Weight
117.13
MOL File
2295-31-0.mol
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2,4-Thiazolidinedione Property

Melting point:
125-127 °C (lit.)
Boiling point:
178-179 °C (19 mmHg)
Density 
1.408 (estimate)
vapor pressure 
0Pa at 25℃
refractive index 
1.5130 (estimate)
Flash point:
178-179°C/19mm
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Crystalline Powder
pka
6.50±0.10(Predicted)
color 
Slightly yellow
Water Solubility 
Soluble in water (30 mg/ml at 3°C), methanol, DMSO, ethanol, and ethyl ether.
BRN 
110700
InChIKey
ZOBPZXTWZATXDG-UHFFFAOYSA-N
LogP
-0.29 at 25℃
CAS DataBase Reference
2295-31-0(CAS DataBase Reference)
NIST Chemistry Reference
2,4-Thiazolidinedione(2295-31-0)
EPA Substance Registry System
2,4-Thiazolidinedione (2295-31-0)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
24/25-36-26
WGK Germany 
3
RTECS 
XJ5775000
TSCA 
Yes
HazardClass 
IRRITANT
HS Code 
29341000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P321Specific treatment (see … on this label).

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
375004
Product name
2,4-Thiazolidinedione
Purity
technical grade, 90%
Packaging
25g
Price
$79
Updated
2024/03/01
Sigma-Aldrich
Product number
375004
Product name
2,4-Thiazolidinedione
Purity
technical grade, 90%
Packaging
100g
Price
$123
Updated
2024/03/01
TCI Chemical
Product number
T1990
Product name
2,4-Thiazolidinedione
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$19
Updated
2024/03/01
TCI Chemical
Product number
T1990
Product name
2,4-Thiazolidinedione
Purity
>98.0%(GC)(T)
Packaging
100g
Price
$51
Updated
2024/03/01
Alfa Aesar
Product number
A13496
Product name
2,4-Thiazolidinedione, 99%
Packaging
25g
Price
$59.65
Updated
2024/03/01
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2,4-Thiazolidinedione Chemical Properties,Usage,Production

Chemical Properties

White to Off-White Powder

Uses

Inhibitor of enzyme

Uses

2,4-Thiazolidinedione may be used in the synthesis of sixteen 5-arylidene-2,4-thiazolidinediones, via ultrasound-promoted aldol condensation reaction. It may be used as starting material for the synthesis of drugs with antihyperglycemic activity.

Definition

ChEBI: A thiazolidenedione carrying oxo substituents at positions 2 and 4.

General Description

2,4-Thiazolidinedione is a well-known peroxisome proliferator-activated receptors (PPAR) activator. Its effect on aging process using kidneys from Fischer 344 rats has been reported. A library of conjugates of 2,4-thiazolidinedione has been synthesized by Knoevenagel condensation followed by reduction using hydrogen gas and Pd/C catalyst. Knoevenagel condensation of various aromatic aldehydes with 2,4-thiazolidinedione in polyethylene glycol-300 has been reported.

Flammability and Explosibility

Not classified

2,4-Thiazolidinedione Preparation Products And Raw materials

Raw materials

Preparation Products

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2,4-Thiazolidinedione Suppliers

Shanghai Qiao Chemical Science Co., Ltd
Tel
021-58892003
Email
info@qiaochem.com
Country
China
ProdList
5902
Advantage
65
shandong XuanHong Pharmaceutical Technology Co.,Ltd
Tel
0531-88801869 15562622698
Fax
0531-88801867
Email
sciencechem@163.com
Country
China
ProdList
276
Advantage
55
Beijing Whale Technology Corporation Ltd.
Tel
010-83694934 13671295325
Email
sales@whalecorporation.com
Country
China
ProdList
128
Advantage
58
Beijing Leaderherb Bio-Tech. Co., LTD.
Tel
010-010-51288246
Email
300abc@sina.com
Country
China
ProdList
68
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
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View Lastest Price from 2,4-Thiazolidinedione manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
2,4-Thiazolidinedione 2295-31-0
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-10-25
Hebei Yanxi Chemical Co., Ltd.
Product
2,4-Thiazolidinedione 2295-31-0
Price
US $30.00-10.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10 tons
Release date
2023-11-17
Hebei Chuanghai Biotechnology Co,.LTD
Product
2,4-Thiazolidinedione 2295-31-0
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-20

2295-31-0, 2,4-ThiazolidinedioneRelated Search:


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