ChemicalBook > CAS DataBase List > Thioflavin T

Thioflavin T

Product Name
Thioflavin T
CAS No.
2390-54-7
Chemical Name
Thioflavin T
Synonyms
THIOFLAVIN T;ThiofL;avin T;CI 49005;CI NO 49005;hioflavineT;Setoflavin T;SETOFLAVINE T;THIOFLAVINE T;BASIC YELLOW 1
CBNumber
CB6676791
Molecular Formula
C17H19ClN2S
Formula Weight
318.86
MOL File
2390-54-7.mol
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Thioflavin T Property

Melting point:
211-212 °C (decomp)
Density 
1.301g/cm3 at 20℃
vapor pressure 
0Pa at 25℃
storage temp. 
Store below +30°C.
solubility 
methanol: soluble1mg/mL
Colour Index 
49005
form 
Powder
color 
Yellow to ochre-yellow
BRN 
3922452
InChI
InChI=1S/C17H19N2S.ClH/c1-12-5-10-15-16(11-12)20-17(19(15)4)13-6-8-14(9-7-13)18(2)3;/h5-11H,1-4H3;1H/q+1;/p-1
InChIKey
JADVWWSKYZXRGX-UHFFFAOYSA-M
SMILES
C1(=[N+](C)C2C=CC(C)=CC=2S1)C1C=CC(N(C)C)=CC=1.[Cl-]
LogP
3.02 at 25℃ and pH7.98
CAS DataBase Reference
2390-54-7(CAS DataBase Reference)
EPA Substance Registry System
Benzothiazolium, 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-, chloride (2390-54-7)
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Safety

Safety Statements 
24/25
RIDADR 
2811
WGK Germany 
3
TSCA 
Yes
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
32041300
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T3516
Product name
Thioflavin T
Purity
used as stain for amyloid
Packaging
5g
Price
$36.6
Updated
2024/03/01
Sigma-Aldrich
Product number
8.40072
Product name
Thioflavine T (C.I.No.49005)
Purity
≥73% sulfur basis
Packaging
5G
Price
$102
Updated
2024/03/01
Sigma-Aldrich
Product number
596200
Product name
Thioflavin T
Packaging
500mg
Price
$123
Updated
2024/03/01
TCI Chemical
Product number
T0558
Product name
Basic Yellow 1
Packaging
25g
Price
$73
Updated
2024/03/01
Alfa Aesar
Product number
J61043
Product name
Thioflavine T, tech. 75%
Packaging
5g
Price
$21.65
Updated
2024/03/01
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Thioflavin T Chemical Properties,Usage,Production

Chemical Properties

yellow to ochre-yellow powder

Uses

Textile dyeing, fluorescent sign paints, in combination with green or blue pigments to produce brilliant greens, phosphotungstic pigments.

Uses

A dye used to visualize beta-amyloid plaques, like those associated with Alzheimer's Disease

Definition

ChEBI: Thioflavine T is an organic chloride salt having 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium as the counterion. It is widely used to visualise and quantify the presence of amyloids, both in vitro and in vivo. It has a role as a fluorochrome, a histological dye and a geroprotector. It contains a thioflavin T cation.

Preparation

4-(6-Methyl-2,3-dihydrobenzo[d]thiazol-2-yl)benzenamine?with methanol and hydrochloric acid or sulfuric acid, at 160 ~ 170 ℃ methylation under pressure.

General Description

Thioflavin T is a benzothiazole dye that increases in fluorescence upon binding to amyloid. Thioflavin T has been used in histology and for protein characterization.

Biochem/physiol Actions

Cell permeable: yes

storage

Store at -20°C

Properties and Applications

colourful green light yellow. Soluble in cold water, soluble in hot water for yellow, easily soluble in ethanol and yellow, with green fluorescent. The strong sulfuric acid to colorless, a green fluorescent, diluted into light yellow.

Standard( Silk ) Light Fastness Persperation Fastness Ironing Fastness Soaping
Fading Stain Fading Stain Fading Stain
C 3 2-3 4 1

Purification Methods

Crystallise the chloride from *benzene/EtOH (1:1). [Beilstein 27 III/IV 5052.]

Thioflavin T Preparation Products And Raw materials

Raw materials

Preparation Products

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Thioflavin T Suppliers

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View Lastest Price from Thioflavin T manufacturers

Hubei Lidu New Material Technology Co., Ltd
Product
THIOFLAVIN T 2390-54-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20tons
Release date
2024-09-23
Hebei Weibang Biotechnology Co., Ltd
Product
Thioflavine T 2390-54-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-20
Hebei Mojin Biotechnology Co., Ltd
Product
Thioflavine T 2390-54-7
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-06-21

2390-54-7, Thioflavin TRelated Search:

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