1-Hydroxy anthraquinone
- Product Name
- 1-Hydroxy anthraquinone
- CAS No.
- 129-43-1
- Chemical Name
- 1-Hydroxy anthraquinone
- Synonyms
- 1-HAQ;NISTC129431;I-0syanthrachinon;1-Hydroxyanthrachinon;4-HYDROXYANTHRAQUINONE;erythroxyanthraquinone;1-HYDROXYANTHRAQUINONE;1-hydroxy-anthraquinon;Anthraquinone Impurity 9;Hydroxyanthraquinone, 1-
- CBNumber
- CB6677576
- Molecular Formula
- C14H8O3
- Formula Weight
- 224.21
- MOL File
- 129-43-1.mol
1-Hydroxy anthraquinone Property
- Melting point:
- 194°C
- Boiling point:
- 325.61°C (rough estimate)
- Density
- 1.2337 (rough estimate)
- refractive index
- 1.5400 (estimate)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Chloroform: 30 mg/ml
- form
- powder to crystal
- pka
- 7.15±0.20(Predicted)
- color
- Light yellow to Brown
- CAS DataBase Reference
- 129-43-1(CAS DataBase Reference)
- IARC
- 2B (Vol. 82) 2002
- NIST Chemistry Reference
- 9,10-Anthracenedione, 1-hydroxy-(129-43-1)
- EPA Substance Registry System
- 9,10-Anthracenedione, 1-hydroxy- (129-43-1)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 36/37/38-40-36
- Safety Statements
- 26-36/37/39-45
- RTECS
- CB7178000
- HS Code
- 2914.69.9000
- Hazardous Substances Data
- 129-43-1(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H320Causes eye irritation
H351Suspected of causing cancer
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313IF exposed or concerned: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- H0354
- Product name
- 1-Hydroxyanthraquinone
- Purity
- >98.0%(HPLC)
- Packaging
- 5g
- Price
- $57
- Updated
- 2025/07/31
- Product number
- H0354
- Product name
- 1-Hydroxyanthraquinone
- Purity
- >98.0%(HPLC)
- Packaging
- 25g
- Price
- $171
- Updated
- 2025/07/31
- Product number
- CS-W000838
- Product name
- 1-Hydroxyanthraquinone
- Packaging
- 5g
- Price
- $104
- Updated
- 2021/12/16
- Product number
- P224
- Product name
- 1-Hydroxyanthraquinone
- Packaging
- 5g
- Price
- $121
- Updated
- 2021/12/16
- Product number
- 119446
- Product name
- 1-Hydroxyanthracene-9,10-dione
- Purity
- 95+%
- Packaging
- 1g
- Price
- $172
- Updated
- 2021/12/16
1-Hydroxy anthraquinone Chemical Properties,Usage,Production
Uses
1-Hydroxyanthraquinone, a naturally occurring compound with oral activity from some plants like Tabebuia avellanedae, exhibits carcinogenic effect[1].
Definition
ChEBI: 1-hydroxyanthraquinone is a monohydroxyanthraquinone.
Synthesis Reference(s)
The Journal of Organic Chemistry, 55, p. 350, 1990 DOI: 10.1021/jo00288a062
in vivo
1-Hydroxyanthraquinone (HA) generates strong DNA repair response and is carcinogenic in rats[1].
| Animal Model: | Thirty rats[1]. |
| Dosage: | 1% HA in diet. |
| Administration: | Diet. |
| Result: | Associated with decreased weight gain which was particularly marked towards the termination of experiment. One of the 30 rats in group 1 (experimental group) died of pneumonia 243 days after the start of experiment. A second rat died in an unnourished state at day 280, demonstrating a large tumor in the colon. Seven animals of the group died spontaneously or were sacrificed upon becoming moribund between 335 and 462 days. A total of 21 rats of group 1 survived until the end of experiment (mean value of total intake of HA/rat was 76.8 g). |
References
[1] H Mori, et al. Carcinogenicity of naturally occurring 1-hydroxyanthraquinone in rats: induction of large bowel, liver and stomach neoplasms. Carcinogenesis. 1990 May;11(5):799-802. DOI:10.1093/carcin/11.5.799
1-Hydroxy anthraquinone Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-Hydroxy anthraquinone manufacturers
- Product
- 1-Hydroxyanthraquinone 129-43-1
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1000kg
- Release date
- 2025-11-07
- Product
- 1-Hydroxy anthraquinone 129-43-1
- Price
- US $25.00/ASSAYS
- Min. Order
- 100ASSAYS
- Purity
- 99.5%
- Supply Ability
- 100 mt
- Release date
- 2024-11-18
- Product
- 1-Hydroxy anthraquinone 129-43-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-01-02