ChemicalBook > CAS DataBase List > 1-Hydroxy anthraquinone

1-Hydroxy anthraquinone

Product Name
1-Hydroxy anthraquinone
CAS No.
129-43-1
Chemical Name
1-Hydroxy anthraquinone
Synonyms
1-HAQ;NISTC129431;I-0syanthrachinon;1-Hydroxyanthrachinon;4-HYDROXYANTHRAQUINONE;erythroxyanthraquinone;1-HYDROXYANTHRAQUINONE;1-hydroxy-anthraquinon;Anthraquinone Impurity 9;Hydroxyanthraquinone, 1-
CBNumber
CB6677576
Molecular Formula
C14H8O3
Formula Weight
224.21
MOL File
129-43-1.mol
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1-Hydroxy anthraquinone Property

Melting point:
194°C
Boiling point:
325.61°C (rough estimate)
Density 
1.2337 (rough estimate)
refractive index 
1.5400 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform: 30 mg/ml
form 
powder to crystal
pka
7.15±0.20(Predicted)
color 
Light yellow to Brown
CAS DataBase Reference
129-43-1(CAS DataBase Reference)
IARC
2B (Vol. 82) 2002
NIST Chemistry Reference
9,10-Anthracenedione, 1-hydroxy-(129-43-1)
EPA Substance Registry System
9,10-Anthracenedione, 1-hydroxy- (129-43-1)
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Safety

Hazard Codes 
Xn
Risk Statements 
36/37/38-40-36
Safety Statements 
26-36/37/39-45
RTECS 
CB7178000
HS Code 
2914.69.9000
Hazardous Substances Data
129-43-1(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H320Causes eye irritation

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
H0354
Product name
1-Hydroxyanthraquinone
Purity
>98.0%(HPLC)
Packaging
5g
Price
$57
Updated
2025/07/31
TCI Chemical
Product number
H0354
Product name
1-Hydroxyanthraquinone
Purity
>98.0%(HPLC)
Packaging
25g
Price
$171
Updated
2025/07/31
ChemScene
Product number
CS-W000838
Product name
1-Hydroxyanthraquinone
Packaging
5g
Price
$104
Updated
2021/12/16
AK Scientific
Product number
P224
Product name
1-Hydroxyanthraquinone
Packaging
5g
Price
$121
Updated
2021/12/16
Matrix Scientific
Product number
119446
Product name
1-Hydroxyanthracene-9,10-dione
Purity
95+%
Packaging
1g
Price
$172
Updated
2021/12/16
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1-Hydroxy anthraquinone Chemical Properties,Usage,Production

Uses

1-Hydroxyanthraquinone, a naturally occurring compound with oral activity from some plants like Tabebuia avellanedae, exhibits carcinogenic effect[1].

Definition

ChEBI: 1-hydroxyanthraquinone is a monohydroxyanthraquinone.

Synthesis Reference(s)

The Journal of Organic Chemistry, 55, p. 350, 1990 DOI: 10.1021/jo00288a062

in vivo

1-Hydroxyanthraquinone (HA) generates strong DNA repair response and is carcinogenic in rats[1].

Animal Model:Thirty rats[1].
Dosage:1% HA in diet.
Administration:Diet.
Result:Associated with decreased weight gain which was particularly marked towards the termination of experiment.
One of the 30 rats in group 1 (experimental group) died of pneumonia 243 days after the start of experiment.
A second rat died in an unnourished state at day 280, demonstrating a large tumor in the colon.
Seven animals of the group died spontaneously or were sacrificed upon becoming moribund between 335 and 462 days.
A total of 21 rats of group 1 survived until the end of experiment (mean value of total intake of HA/rat was 76.8 g).

References

[1] H Mori, et al. Carcinogenicity of naturally occurring 1-hydroxyanthraquinone in rats: induction of large bowel, liver and stomach neoplasms. Carcinogenesis. 1990 May;11(5):799-802. DOI:10.1093/carcin/11.5.799

1-Hydroxy anthraquinone Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Hydroxy anthraquinone Suppliers

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View Lastest Price from 1-Hydroxy anthraquinone manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
1-Hydroxyanthraquinone 129-43-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000kg
Release date
2025-11-07
Hebei Chuanghai Biotechnology Co., Ltd
Product
1-Hydroxy anthraquinone 129-43-1
Price
US $25.00/ASSAYS
Min. Order
100ASSAYS
Purity
99.5%
Supply Ability
100 mt
Release date
2024-11-18
Career Henan Chemical Co
Product
1-Hydroxy anthraquinone 129-43-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-01-02

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