Cefcapene

Product Name: Cefcapene
CAS No.: 135889-00-8
Chemical Name: Cefcapene
Synonyms: CEFCAPENE;s1006;Cefcamate;Cefcapine;Cefcapinaxil;Cefcarpinic Acid;CEFCAPENE Impurity;Cefcapene Impurity 5;Cefcapene Impurity 7;Cefcapene pivoxil free acid
CBNumber: CB6680909
Molecular Formula: C17H19N5O6S2
Formula Weight: 453.49
MOL File: 135889-00-8.mol

More

Less

Cefcapene Property

Boiling point:: 936.0±65.0 °C(Predicted)
Density: 1.63
pka: 2.58±0.50(Predicted)

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

TRC

Product number: C242545
Product name: Cefcapene
Packaging: 25mg
Price: $4125
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0007951
Product name: CEFCAPENE
Purity: 95.00%
Packaging: 25MG
Price: $4908.75
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0007951
Product name: CEFCAPENE
Purity: 95.00%
Packaging: 1MG
Price: $925.05
Updated: 2021/12/16

More

Less

Cefcapene Chemical Properties,Usage,Production

Uses

Cefcapene is a metabolite of Cefcapene Pivoxil (C242550). Antibacterial, orally absorbed cephalosporin that is used in the treatment of bacterial infections.

Definition

ChEBI: Cefcapene is a cephalosporin compound having (carbamoyloxy)methyl and N-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)pent-2-enoyl]amino side-groups. It is used (generally as the corresponnding pivaloyloxymethyl ester prodrug) as an oral antibacterial. It has a role as an antibacterial drug. It is a cephalosporin, a carboxylic acid, a carbamate ester, an enamide, a member of 1,3-thiazoles and a secondary carboxamide.

Antimicrobial activity

A semisynthetic cephalosporin formulated for oral administration as the prodrug ester, cefcapene pivoxil. Activity and uses are similar to those of cefditoren.
Available in Japan.

Pharmacokinetics

Cefcapene is a semisynthetic third-generation cephalosporin with antibacterial activity. Cefcapene binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
6436055

Cefcapene Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Cefcapene Suppliers

Canada 1 China 74 India 2 United Kingdom 3 United States 7 Global 87

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15402
Advantage: 60

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527768850
Email: 1791901229@qq.com
Country: China
ProdList: 8836
Advantage: 52

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-83725681-603
Fax: +86 755 28094224
Country: China
ProdList: 4496
Advantage: 50

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12335
Advantage: 58

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
Advantage: 58

Clearsynth Labs Limited

Tel: +91-22-26355700
Fax: +91-22-26355701
Email: info@clearsynth.com
Country: India
ProdList: 9679
Advantage: 58

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18070
Advantage: 56

Shanghai YuLue Chemical Co., Ltd.

Tel: 021-60345187 13671753212
Fax: 021-34702061
Email: lzz841106@aliyun.com
Country: China
ProdList: 10274
Advantage: 55

Credit Asia Chemical Co., Ltd.

Tel: +86 (21) 61124340
Fax: +86 (21) 6129-4103
Country: China
ProdList: 9756
Advantage: 58

Wellman Pharmaceutical Group Limited

Tel: 027-83778875 15807197853
Fax: 027-83991220
Email: 15807197853@163.com
Country: China
ProdList: 4028
Advantage: 58

More

Less

View Lastest Price from Cefcapene manufacturers

Guangzhou Tosun Pharmaceutical Ltd

Product: Cefcapene Impurity 7 135889-00-8
Price: US $0.00-0.00/mg
Min. Order: 5mg
Purity: 95%+
Supply Ability: 1000
Release date: 2024-12-18

ShenZhen H&D Pharmaceutical Technology Co., LTD

Product: Cefcapene 135889-00-8
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 0.98
Supply Ability: 10g
Release date: 2024-04-25

Career Henan Chemical Co

Product: (6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-1-oxo-2-pentenyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 135889-00-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2019-09-04

135889-00-8, CefcapeneRelated Search:

(Z)-2-(2-tert-Butoxycarbonylaminothiazol-4-yl)-2-pentenoic acid Precursor of cefcapene diisopropylanmine salt Cefetamet hydrochloride cefcapene pivoxil hydrochloride CEFCAPENE PIVOXIL HCL CEFCAPENE PIVOXIL-D9 Cefcapene Pivoxil Hydrochlrode JP CEFCAPENE PIVOXIL Cefcapene Hydroxymethyl-7-Aminocephalosporanic acid 7-AMCA

CEFCAPENE

s1006

(6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-1-oxo-2-pentenyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7R)-7-[(Z)-2-(2-Aminothiazol-4-yl)-2-pentenoylamino]-8-oxo-3-(carbamoyloxymethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(7R)-7-[[(Z)-2-(2-Amino-4-thiazolyl)-1-oxo-2-pentenyl]amino]-3-[(carbamoyloxy)methyl]cepham-3-ene-4-carboxylic acid

Cefcamate

Cefcapene pivoxil free acid

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,3-[[(aMinocarbonyl)oxy]Methyl]-7-[[(2Z)-2-(2-aMino-4-thiazolyl)-1-oxo-2-penten-1-yl]aMino]-8-oxo-,(6R,7R)-

(6R,7R)-3-[[(AMinocarbonyl)oxy]Methyl]-7-[[(2Z)-2-(2-aMino-4-thiazolyl)-1-oxo-2-penten-1-yl]aMino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid

(6R,7R)-7-[[(Z)-2-(2-amino-1,3-thiazol-4-yl)pent-2-enoyl]amino]-3-(carbamoyloxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-1-oxo-2-pentenyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic

Cefcapene Impurity 5

Cefcapene Pivoxil Impurity 1

Cefcapene Pivoxil Impurity 4 (Cefcapene)

Cefcapene Impurity 7

(6R,7R)-7-[[(Z)-2-(2-amino-1,3-thiazol-4-yl)pent-2-enoyl]amino]-3-(carbamoyloxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicaci

Cefcarpinic Acid

Cefcapene Pivoxil Hydrolized Impurity 1

Cefcapene pivoxil Impurity 16

Cefcapene pivoxil Impurity 10

Cefcapinaxil

CEFCAPENE Impurity

Cefcapine

135889-00-8

C23H29N5O8S2

C17H19N5O6S2

Chiral Reagents

Heterocycles

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals

Sulfur & Selenium Compounds