Cefcapene pivoxil

Product Name: Cefcapene pivoxil
CAS No.: 105889-45-0
Chemical Name: Cefcapene pivoxil
Synonyms: Fumax;S-1108;Flumax;Cefcapene Piroxil;CEFCAPENE PIVOXIL;Cefcapene Impurity 3;Cefcapene pivoxil USP/EP/BP;Cefcapene Pivoxil Impurities;Cefcapene Pivoxil See C242555;Cefcapene pivoxil Impurity 13
CBNumber: CB3680908
Molecular Formula: C23H29N5O8S2
Formula Weight: 567.64
MOL File: 105889-45-0.mol

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Cefcapene pivoxil Property

Melting point:: 158-164°C
Boiling point:: 888.4±65.0 °C(Predicted)
Density: 1.47±0.1 g/cm3(Predicted)
solubility: DMSO, Water( warm)
form: Solid
pka: 11.33±0.60(Predicted)
color: Off-White

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: C242550
Product name: CefcapenePivoxil
Packaging: 10mg
Price: $155
Updated: 2021/12/16

AK Scientific

Product number: G657
Product name: Cefcapenepivoxil
Packaging: 25mg
Price: $98
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC37919
Product name: Cefcapene pivoxil 722ug/mg
Packaging: 10mg
Price: $104.7
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC37919
Product name: Cefcapene pivoxil 722ug/mg
Packaging: 25mg
Price: $167.5
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC37919
Product name: Cefcapene pivoxil 722ug/mg
Packaging: 50mg
Price: $268
Updated: 2021/12/16

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Cefcapene pivoxil Chemical Properties,Usage,Production

Description

Flomox was launched in Japan as an orally active cephalosporin for respiratory and urinary tract infections, heptatic infections, ophthalmological and otorhinolarynological infections, skinkoft tissue infections, and for use in gynacology, dentistry and oral surgery. It can be prepared by condesation of 2(Z)-(2-(t-butoxycarbonylamino) thiazol-4-yl)-2-pentenoic acid with 7-amino-3-(carbanoyloxymethyl)- 3-cephem-4-carboxylic acid pivaloyl methyl ester followed by deprotection. Flomox is highly active against a wide variety of Gram-positive and Gram-negative bacteria, except for several strains such as Pseudomonas aeruginosa and enterococci, by acting as a cell wall synthesis inhibitor (β-lactamase stability against TEM-1 type β-lactamases) and is more effective than cefaclor and cefdinir. Absorption is improved by the pivaloyloxymethyl ester group which is easily lost by deesterification during GI absorption to produce the biologically active form. The pivalic acid generated quickly conjugates with carnitine and is excreted in the urine. The drop in plasma levels of carnitine was dose dependent and returned to normal levels upon termination of treatment.

Chemical Properties

Off-White Solid

Originator

Shionogi (Japan)

Uses

Antibacterial. Orally absorbed cephalosporin; ester prodrug of the active free acid metabolite, Cefcapene.

brand name

Flomox

Cefcapene pivoxil Preparation Products And Raw materials

Raw materials

Phosphoric acid Anisole Trifluoroacetic acid Methanesulfonyl chloride Iodomethane

Preparation Products

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Cefcapene pivoxil Suppliers

Canada 1 China 90 Germany 1 India 7 United Kingdom 2 United States 8 Global 109

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Email: sales@capotchem.com
Country: China
ProdList: 18207
Advantage: 66

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527768850
Email: 1791901229@qq.com
Country: China
ProdList: 8836
Advantage: 52

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 14055
Advantage: 65

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12335
Advantage: 58

NCE Biomedical Co.,Ltd.

Tel: 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
Fax: +86-27-87599188
Country: China
ProdList: 1493
Advantage: 55

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Fax: 025-57019371
Email: sales@sunlidabio.com
Country: China
ProdList: 3239
Advantage: 55

Wuhan DKY Technology Co.,Ltd.

Tel: 27-81302488 18007166089
Fax: 027-81302088
Email: info@dkybpc.com
Country: China
ProdList: 1866
Advantage: 58

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18070
Advantage: 56

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View Lastest Price from Cefcapene pivoxil manufacturers

Guangzhou PI PI BIOTECH INC

Product: Cefcapene Pivoxil 105889-45-0
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 90%+
Supply Ability: 10g
Release date: 2021-09-04

Guangzhou PI PI BIOTECH INC

Product: Cefcapene Pivoxil Impurities 105889-45-0
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 90%+
Supply Ability: 10g
Release date: 2021-09-04

Zhuozhou Wenxi import and Export Co., Ltd

Product: Cefcapene pivoxil 105889-45-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

105889-45-0, Cefcapene pivoxilRelated Search:

Thiophanate-methyl Tribenuron methyl Methyl acetate 2-(2-Aminothiazol-4-yl)glyoxylic acid 2-Aminothiazole-4-acetic acid Sodium cefamandole Fosthiazate Cefamandole Benzothiazole Methyl salicylate 2-Mercaptobenzothiazole Cefpodoxime proxetil Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) Cefetamet pivoxyl Kresoxim-methyl METSULFURON METHYL Methyl Methyl bromide

(6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-1-oxo-2-pentenyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid, (2,2-Dimethyl-1-oxopropoxy)methyl Ester

Fumax

S-1108

Cefcapene Piroxil

Flumax

CEFCAPENE PIVOXIL

(6R,7R)-7-[[(Z)-2-(2-amino-4-thiazolyl)-1-oxopent-2-enyl]amino]-3-(carbamoyloxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (2,2-dimethyl-1-oxopropoxy)methyl ester

Cefcapene Pivoxil See C242555

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,3-[[(aMinocarbonyl)oxy]Methyl]-7-[[(2Z)-2-(2-aMino-4-thiazolyl)-1-oxo-2-penten-1-yl]aMino]-8-oxo-,(2,2-diMethyl-1-oxopropoxy)Methyl ester, (6R,7R)-

Cefcapene Impurity 3

(6R,7R)-(pivaloyloxy)methyl7-((Z)-2-(2-aminothiazol-4-yl)pent-2-enamido)-3-((carbamoyloxy)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Cefcapene pivoxil USP/EP/BP

Cefcapene Pivoxil Impurities

Cefditoren pivoxilQ: What is Cefditoren pivoxil Q: What is the CAS Number of Cefditoren pivoxil Q: What is the storage condition of Cefditoren pivoxil Q: What are the applications of Cefditoren pivoxil

105889-45-0 Cefcapene pivoxil

Cefcapene pivoxil Powder USP Standard

Cefcapene pivoxil Impurity 13

105889-45-0

Chiral Reagents

Intermediates & Fine Chemicals

Pharmaceuticals

Heterocycles

Metabolites & Impurities

Sulfur & Selenium Compounds

Pharmaceutical intermediate