Cefcapene pivoxil
- Product Name
- Cefcapene pivoxil
- CAS No.
- 105889-45-0
- Chemical Name
- Cefcapene pivoxil
- Synonyms
- Fumax;S-1108;Flumax;Cefcapene Piroxil;CEFCAPENE PIVOXIL;Cefcapene Impurity 3;Cefcapene pivoxil USP/EP/BP;Cefcapene Pivoxil Impurities;Cefcapene Pivoxil See C242555;Cefcapene pivoxil Impurity 13
- CBNumber
- CB3680908
- Molecular Formula
- C23H29N5O8S2
- Formula Weight
- 567.64
- MOL File
- 105889-45-0.mol
Cefcapene pivoxil Property
- Melting point:
- 158-164°C
- Boiling point:
- 888.4±65.0 °C(Predicted)
- Density
- 1.47±0.1 g/cm3(Predicted)
- solubility
- DMSO, Water( warm)
- form
- Solid
- pka
- 11.33±0.60(Predicted)
- color
- Off-White
N-Bromosuccinimide Price
- Product number
- C242550
- Product name
- CefcapenePivoxil
- Packaging
- 10mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- FC37919
- Product name
- Cefcapene pivoxil 722ug/mg
- Packaging
- 25mg
- Price
- $167.5
- Updated
- 2021/12/16
- Product number
- G657
- Product name
- Cefcapenepivoxil
- Packaging
- 25mg
- Price
- $98
- Updated
- 2021/12/16
- Product number
- FC37919
- Product name
- Cefcapene pivoxil 722ug/mg
- Packaging
- 10mg
- Price
- $104.7
- Updated
- 2021/12/16
- Product number
- FC37919
- Product name
- Cefcapene pivoxil 722ug/mg
- Packaging
- 50mg
- Price
- $268
- Updated
- 2021/12/16
Cefcapene pivoxil Chemical Properties,Usage,Production
Description
Flomox was launched in Japan as an orally active cephalosporin for respiratory and urinary tract infections, heptatic infections, ophthalmological and otorhinolarynological infections, skinkoft tissue infections, and for use in gynacology, dentistry and oral surgery. It can be prepared by condesation of 2(Z)-(2-(t-butoxycarbonylamino) thiazol-4-yl)-2-pentenoic acid with 7-amino-3-(carbanoyloxymethyl)- 3-cephem-4-carboxylic acid pivaloyl methyl ester followed by deprotection. Flomox is highly active against a wide variety of Gram-positive and Gram-negative bacteria, except for several strains such as Pseudomonas aeruginosa and enterococci, by acting as a cell wall synthesis inhibitor (β-lactamase stability against TEM-1 type β-lactamases) and is more effective than cefaclor and cefdinir. Absorption is improved by the pivaloyloxymethyl ester group which is easily lost by deesterification during GI absorption to produce the biologically active form. The pivalic acid generated quickly conjugates with carnitine and is excreted in the urine. The drop in plasma levels of carnitine was dose dependent and returned to normal levels upon termination of treatment.
Chemical Properties
Off-White Solid
Originator
Shionogi (Japan)
Uses
Antibacterial. Orally absorbed cephalosporin; ester prodrug of the active free acid metabolite, Cefcapene.
brand name
Flomox
Cefcapene pivoxil Preparation Products And Raw materials
Raw materials
Preparation Products
Cefcapene pivoxil Suppliers
- Tel
- --
- Fax
- --
- sales@chemos-group.com
- Country
- Germany
- ProdList
- 6350
- Advantage
- 71
View Lastest Price from Cefcapene pivoxil manufacturers
- Product
- Cefcapene Pivoxil 105889-45-0
- Price
- US $0.00-0.00/mg
- Min. Order
- 10mg
- Purity
- 90%+
- Supply Ability
- 10g
- Release date
- 2021-09-04
- Product
- Cefcapene Pivoxil Impurities 105889-45-0
- Price
- US $0.00-0.00/mg
- Min. Order
- 10mg
- Purity
- 90%+
- Supply Ability
- 10g
- Release date
- 2021-09-04
- Product
- Cefcapene pivoxil 105889-45-0
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09