ChemicalBook > CAS DataBase List > Cefcapene pivoxil

Cefcapene pivoxil

Product Name
Cefcapene pivoxil
CAS No.
105889-45-0
Chemical Name
Cefcapene pivoxil
Synonyms
Fumax;S-1108;Flumax;Cefcapene Piroxil;CEFCAPENE PIVOXIL;Cefcapene Impurity 3;Cefcapene pivoxil USP/EP/BP;Cefcapene Pivoxil Impurities;Cefcapene Pivoxil See C242555;Cefcapene pivoxil Impurity 13
CBNumber
CB3680908
Molecular Formula
C23H29N5O8S2
Formula Weight
567.64
MOL File
105889-45-0.mol
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Cefcapene pivoxil Property

Melting point:
158-164°C
Boiling point:
888.4±65.0 °C(Predicted)
Density 
1.47±0.1 g/cm3(Predicted)
solubility 
DMSO, Water( warm)
form 
Solid
pka
11.33±0.60(Predicted)
color 
Off-White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
C242550
Product name
CefcapenePivoxil
Packaging
10mg
Price
$155
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC37919
Product name
Cefcapene pivoxil 722ug/mg
Packaging
25mg
Price
$167.5
Updated
2021/12/16
AK Scientific
Product number
G657
Product name
Cefcapenepivoxil
Packaging
25mg
Price
$98
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC37919
Product name
Cefcapene pivoxil 722ug/mg
Packaging
10mg
Price
$104.7
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC37919
Product name
Cefcapene pivoxil 722ug/mg
Packaging
50mg
Price
$268
Updated
2021/12/16
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Cefcapene pivoxil Chemical Properties,Usage,Production

Description

Flomox was launched in Japan as an orally active cephalosporin for respiratory and urinary tract infections, heptatic infections, ophthalmological and otorhinolarynological infections, skinkoft tissue infections, and for use in gynacology, dentistry and oral surgery. It can be prepared by condesation of 2(Z)-(2-(t-butoxycarbonylamino) thiazol-4-yl)-2-pentenoic acid with 7-amino-3-(carbanoyloxymethyl)- 3-cephem-4-carboxylic acid pivaloyl methyl ester followed by deprotection. Flomox is highly active against a wide variety of Gram-positive and Gram-negative bacteria, except for several strains such as Pseudomonas aeruginosa and enterococci, by acting as a cell wall synthesis inhibitor (β-lactamase stability against TEM-1 type β-lactamases) and is more effective than cefaclor and cefdinir. Absorption is improved by the pivaloyloxymethyl ester group which is easily lost by deesterification during GI absorption to produce the biologically active form. The pivalic acid generated quickly conjugates with carnitine and is excreted in the urine. The drop in plasma levels of carnitine was dose dependent and returned to normal levels upon termination of treatment.

Chemical Properties

Off-White Solid

Originator

Shionogi (Japan)

Uses

Antibacterial. Orally absorbed cephalosporin; ester prodrug of the active free acid metabolite, Cefcapene.

brand name

Flomox

Cefcapene pivoxil Preparation Products And Raw materials

Raw materials

Phosphoric acid Anisole Trifluoroacetic acid Methanesulfonyl chloride Iodomethane

Preparation Products

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Cefcapene pivoxil Suppliers

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View Lastest Price from Cefcapene pivoxil manufacturers

Guangzhou PI PI BIOTECH INC
Product
Cefcapene Pivoxil 105889-45-0
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
90%+
Supply Ability
10g
Release date
2021-09-04
Guangzhou PI PI BIOTECH INC
Product
Cefcapene Pivoxil Impurities 105889-45-0
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
90%+
Supply Ability
10g
Release date
2021-09-04
Zhuozhou Wenxi import and Export Co., Ltd
Product
Cefcapene pivoxil 105889-45-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

105889-45-0, Cefcapene pivoxilRelated Search:

Thiophanate-methyl Tribenuron methyl Methyl acetate 2-(2-Aminothiazol-4-yl)glyoxylic acid 2-Aminothiazole-4-acetic acid Sodium cefamandole Fosthiazate Cefamandole Benzothiazole Methyl salicylate 2-Mercaptobenzothiazole Cefpodoxime proxetil Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) Cefetamet pivoxyl Kresoxim-methyl METSULFURON METHYL Methyl Methyl bromide

  • (6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-1-oxo-2-pentenyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid, (2,2-Dimethyl-1-oxopropoxy)methyl Ester
  • Fumax
  • S-1108
  • Cefcapene Piroxil
  • Flumax
  • CEFCAPENE PIVOXIL
  • (6R,7R)-7-[[(Z)-2-(2-amino-4-thiazolyl)-1-oxopent-2-enyl]amino]-3-(carbamoyloxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (2,2-dimethyl-1-oxopropoxy)methyl ester
  • Cefcapene Pivoxil See C242555
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,3-[[(aMinocarbonyl)oxy]Methyl]-7-[[(2Z)-2-(2-aMino-4-thiazolyl)-1-oxo-2-penten-1-yl]aMino]-8-oxo-,(2,2-diMethyl-1-oxopropoxy)Methyl ester, (6R,7R)-
  • Cefcapene Impurity 3
  • (6R,7R)-(pivaloyloxy)methyl7-((Z)-2-(2-aminothiazol-4-yl)pent-2-enamido)-3-((carbamoyloxy)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
  • Cefcapene pivoxil USP/EP/BP
  • Cefcapene Pivoxil Impurities
  • Cefditoren pivoxilQ: What is Cefditoren pivoxil Q: What is the CAS Number of Cefditoren pivoxil Q: What is the storage condition of Cefditoren pivoxil Q: What are the applications of Cefditoren pivoxil
  • 105889-45-0 Cefcapene pivoxil
  • Cefcapene pivoxil Powder USP Standard
  • Cefcapene pivoxil Impurity 13
  • 105889-45-0
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  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Heterocycles
  • Metabolites & Impurities
  • Sulfur & Selenium Compounds
  • Pharmaceutical intermediate