5,8,11-EICOSATRIYNOIC ACID

Product Name: 5,8,11-EICOSATRIYNOIC ACID
CAS No.: 13488-22-7
Chemical Name: 5,8,11-EICOSATRIYNOIC ACID
Synonyms: ETI;EICOSATRIYNOIC ACID;5,8,11-Icosatriynoic acid;Icosa-5,8,11-triynoic acid;5,8,11-EICOSATRIYNOIC ACID;OWYNLPMPYBYKJP-UHFFFAOYSA-N;5,8,11-EICOSATRIYNOIC ACID Basic information;5,8,11-EICOSATRIYNOIC ACID ISO 9001：2015 REACH
CBNumber: CB6705237
Molecular Formula: C20H28O2
Formula Weight: 300.44
MOL File: 13488-22-7.mol

More

Less

5,8,11-EICOSATRIYNOIC ACID Property

Melting point:: 70.5-71.5 °C
Boiling point:: 473.8±40.0 °C(Predicted)
Density: 0.990±0.06 g/cm3(Predicted)
storage temp.: −20°C
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Off-white solid.
pka: 4.61±0.10(Predicted)
color: Pale Yellow to Pale Beige
Stability:: Light Sensitive

More

Less

Safety

WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 90200
Product name: 5,8,11-Eicosatriynoic Acid
Purity: ≥99%
Packaging: 1mg
Price: $85
Updated: 2024/03/01

Cayman Chemical

Product number: 90200
Product name: 5,8,11-Eicosatriynoic Acid
Purity: ≥99%
Packaging: 5mg
Price: $359
Updated: 2024/03/01

Cayman Chemical

Product number: 90200
Product name: 5,8,11-Eicosatriynoic Acid
Purity: ≥99%
Packaging: 10mg
Price: $633
Updated: 2024/03/01

TRC

Product number: E936910
Product name: ETI
Packaging: 250mg
Price: $1325
Updated: 2021/12/16

ApexBio Technology

Product number: C5811
Product name: 5,8,11-EicosatriynoicAcid
Packaging: 10mg
Price: $732
Updated: 2021/12/16

More

Less

5,8,11-EICOSATRIYNOIC ACID Chemical Properties,Usage,Production

Uses

ETI is a leukotriene antagonist and selective 5-LO (5-lipoxygenase) inhibitor.

Definition

ChEBI: A C20 polyunsaturated fatty acid having three triple bonds in the 5-, 8- and 11-positions.

Biological Activity

5,8,11-eicosatriynoic acid is a selective inhibitor of lipoxygenases with id50 values of 24 μm and 340 μm for n-8 lipoxygenase and fatty acid cycle-oxygenase , respectively[1][2].fatty acid cycle-oxygenase and n-8 lipoxygenase catalyze the initial reactions which lead to the formation of three major arachidonic acid metabolites in human platelets. in several tissues, these two enzymes act concomitantly on arachidonic acid [1].5,8,11-eicosatriynoic acid (5,8,11-et) is a selective inhibitor of lipoxygenases with id50 values of 24 μm and 340 μm for n-8 lipoxygenase and fatty acid cycle-oxygenase, respectively. 5,8,11-eicosatriynoic acid was useful for studies on physiological and pathophysiological roles of 12 l-hydroxy-5,8,10,14-eicosatetraenoic acid formation in various tissues [1]. in mouse mastocytoma cells, 5,8,11-eicosatriynoic acid inhibited a23187 and l-cysteine induced leukotriene c (ltc4) biosynthesis with id50 value of 5 μm [2].

References

[1]. hammarstrm s. selective inhibition of platelet n-8 lipoxygenase by 5,8,11-eicosatriynoic acid. biochim biophys acta. 1977 jun 22;487(3):517-9.
[2]. orning l, hammarstrm s. inhibition of leukotriene c and leukotriene d biosynthesis. j biol chem. 1980 sep 10;255(17):8023-6.

5,8,11-EICOSATRIYNOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

5,8,11-EICOSATRIYNOIC ACID Suppliers

China 38 Germany 1 India 1 Switzerland 3 United Kingdom 1 United States 14 Global 58

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

Shenzhen Regent Biochemical Technology Co., Ltd.

Tel: 0755-0755-85201366 18938635012
Fax: 0755-85201366
Email: sales@regentsciences.com
Country: China
ProdList: 9375
Advantage: 58

Dideu Industries Group Limited

Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Country: China
ProdList: 22787
Advantage: 58

Hebei Binshare New Material Co. Ltd

Tel: +8618633865755
Email: china01@hbbinshare.com
Country: CHINA
ProdList: 955
Advantage: 58

Shijiazhuang Erche Biotechnology Co., Ltd

Tel: 8613343119830 13343119830
Fax: QQ: 956730943
Email: info07@byyq-cn.com
Country: CHINA
ProdList: 387
Advantage: 58

Shanghai Dumi Biotechnology Co.,ltd

Tel: +8617172178855 17172178855
Email: aimee@chinadumi.com
Country: CHINA
ProdList: 225
Advantage: 58

Shanghai Dumi Biotechnology Co.,LTD

Tel: +8617172178822 15373897440
Email: cassie@chinadumi.com
Country: CHINA
ProdList: 103
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44806
Advantage: 58

MedBioPharmaceutical Technology Inc

Tel: 021-69568360 18916172912
Email: order@med-bio.cn
Country: China
ProdList: 8140
Advantage: 58

SHANGHAI ZZBIO CO., LTD.

Tel: 15102117276 19921389125
Email: tech@zzbioco.com
Country: China
ProdList: 12065
Advantage: 58

Tel: 4008-099-669
Email: 23419001name@qq.com
Country: CHINA
ProdList: 73043
Advantage: 58

Hangzhou FandaChem Co.,Ltd.

Tel: +8615858145714
Fax: +86-571-56059825
Email: FandaChem@Gmail.com
Country: China
ProdList: 8780
Advantage: 55

Henan Bao Enluo International TradeCo.，LTD

Tel: +86-17331933971 +86-17331933971
Fax: deasea125996@gmail.com
Email: deasea125996@gmail.com
Country: China
ProdList: 2472
Advantage: 58

Hebei Anda Technology Co., LTD

Tel: +86-19831998802
Email: 106@hebeianda.cn
Country: China
ProdList: 278
Advantage: 58

Hebei Gongyuan New Material Technology Co., Ltd.

Tel: +8617331136198
Email: Grace@hebeisyjl.com
Country: China
ProdList: 479
Advantage: 58

Hangzhou MolCore BioPharmatech Co.,Ltd.

Tel: +86-057181025280; +8617767106207
Fax: 0571-85806285
Email: sales@molcore.com
Country: China
ProdList: 49734
Advantage: 58

Shanghai Hao Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: market@xlswkj.com
Country: CHINA
ProdList: 6793
Advantage: 58

Shanghai Hao Zhun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: info@zzsrm.com
Country: CHINA
ProdList: 6650
Advantage: 58

Beijing Taize Jiaye Technology Development Co., Ltd.

Tel: --
Fax: --
Country: CHINA
ProdList: 6050
Advantage: 58

Beijing Dongge Boye Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 1861586486@qq.com
Country: CHINA
ProdList: 6648
Advantage: 58

Fujifilm Wako (Guangzhou) Trading Co., Ltd.

Tel: --
Fax: --
Country: CHINA
ProdList: 1409
Advantage: 58

Shanghai Silk Dragon Biological Technology Co., Ltd.

Tel: --
Fax: --
Country: CHINA
ProdList: 3988
Advantage: 58

Shanghai Hao Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: shxiyuanbio@163.com
Country: CHINA
ProdList: 6906
Advantage: 58

Morning Student Science and Technology (Guangzhou) Co., Ltd.

Tel: --
Fax: --
Email: chenxue_gz@163.com
Country: CHINA
ProdList: 6600
Advantage: 58

Xiamen Huijia Biological Technology Co., Ltd.

Tel: --
Fax: --
Country: CHINA
ProdList: 6973
Advantage: 58

Boao Pike

Tel: --
Fax: --
Email: lyn@biopike.com.cn
Country: CHINA
ProdList: 6629
Advantage: 58

Resenbio

Tel: --
Fax: --
Email: sales@xarxbio.com
Country: China
ProdList: 1774
Advantage: 50

Beijing Lebo Biotechnology Co., Ltd.

Tel: --
Fax: --
Country: CHINA
ProdList: 6057
Advantage: 58

Shenzhen Xinbosheng Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: service@neobioscience.com
Country: CHINA
ProdList: 6151
Advantage: 58

Shanghai Yaoyun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: 912529879@qq.com
Country: CHINA
ProdList: 6835
Advantage: 58

Shanghai Minmin Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 1914109725@qq.com
Country: CHINA
ProdList: 6518
Advantage: 58

Shanghai Jijin Chemical Technology Co., Ltd.

Tel: --
Fax: --
Email: jijinhuaxue@sina.com
Country: CHINA
ProdList: 6606
Advantage: 58

Shanghai Ziqi Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: 2453006496@qq.com
Country: CHINA
ProdList: 6184
Advantage: 58

Xiamen Research Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 1562893815@qq.com
Country: CHINA
ProdList: 6936
Advantage: 58

Shanghai Weiwei Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: sales@wheybio.com
Country: CHINA
ProdList: 4398
Advantage: 58

Guangzhou WeiBo Chemical Co., Ltd.

Tel: --
Fax: --
Email: weibochem@163.com
Country: China
ProdList: 6187
Advantage: 67

Advanced Technology & Industrial Co., Ltd.

Tel: --
Fax: --
Email: sales@advtechind.com
Country: China
ProdList: 6523
Advantage: 75

More

Less

View Lastest Price from 5,8,11-EICOSATRIYNOIC ACID manufacturers

Henan Bao Enluo International TradeCo.，LTD

Product: 5,8,11-EICOSATRIYNOIC ACID 13488-22-7
Price: US $50.00/kg
Min. Order: 1kg
Purity: 99.9%
Supply Ability: 10000MT
Release date: 2023-07-24

Guangzhou Sunton Biotechnology Co., Ltd.

Product: 5,8,11-EICOSATRIYNOIC ACID 13488-22-7
Price: US $50.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 tons
Release date: 2021-05-07

Hebei Anda Technology Co., LTD

Product: ETI 13488-22-7
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: Ex 20 tons
Release date: 2022-10-21

13488-22-7, 5,8,11-EICOSATRIYNOIC ACIDRelated Search:

Baicalein PD 146176 CDC Caffeic acid Esculetin REV 5901 BW B70C 15(S)-HEDE 5,8,11-EICOSATRIYNOIC ACID 5-HEXYN-1-OL 1,4-DECADIYNE 3-UNDECYNE 5-HEXYNOIC ACID 1,4-HEPTADIYNE 1,4-PENTADIYNE 1,4-HEXADIYNE 2,5-HEPTADIYNE 3-DODECYNE

EICOSATRIYNOIC ACID

ETI

5,8,11-EICOSATRIYNOIC ACID

Icosa-5,8,11-triynoic acid

5,8,11-Icosatriynoic acid

OWYNLPMPYBYKJP-UHFFFAOYSA-N

5,8,11-EICOSATRIYNOIC ACID Basic information

5,8,11-EICOSATRIYNOIC ACID ISO 9001：2015 REACH

13488-22-7

Biochemicals and Reagents

BioChemical

L to O

Lipoxygenase (5 and 12-); does not inhibit cyclooxygenase.

Enzymes, Inhibitors, and Substrates

Enzyme Inhibitors

Enzyme Inhibitors by Enzyme