ChemicalBook > CAS DataBase List > (S)-AMPA

(S)-AMPA

Product Name
(S)-AMPA
CAS No.
83643-88-3
Chemical Name
(S)-AMPA
Synonyms
AMQ;(S)-AMPA;glutamate-AMPA;L-AMPA, S-AMPA;(S) AMPA,(S)AMPA;(S)-AMPA (mM/ml);(S)-A-amino-3-hydroxy-5-methylisoxazole -4-propio;(S)-amino-3-hydroxy-5-methylisoxazolepropionic acid;(S)-A-AMINO-3-HYDROXY-5-METHYLISOXAZOLE -4-PROPIONI;(S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionicacid
CBNumber
CB6711838
Molecular Formula
C7H10N2O4
Formula Weight
186.17
MOL File
83643-88-3.mol
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(S)-AMPA Property

alpha 
D28 -21 ±2° (c = 0.19 in water)
Density 
1.386±0.06 g/cm3(Predicted)
storage temp. 
Store at RT
form 
White to off-white powder.
pka
2.15±0.10(Predicted)
color 
White
Water Solubility 
Soluble to 100 mM in water
CAS DataBase Reference
83643-88-3(CAS DataBase Reference)
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Safety

Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A0326
Product name
(S)-AMPA
Purity
≥98%
Packaging
1mg
Price
$246
Updated
2024/03/01
Sigma-Aldrich
Product number
A0326
Product name
(S)-AMPA
Purity
≥98%
Packaging
5mg
Price
$847
Updated
2024/03/01
Alfa Aesar
Product number
J65847
Product name
(S)-alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
Packaging
5mg
Price
$176
Updated
2021/12/16
Tocris
Product number
0254
Product name
(S)-AMPA
Purity
≥99%(HPLC)
Packaging
10
Price
$279
Updated
2021/12/16
Tocris
Product number
0254
Product name
(S)-AMPA
Purity
≥99%(HPLC)
Packaging
50
Price
$1109
Updated
2021/12/16
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(S)-AMPA Chemical Properties,Usage,Production

Uses

Active enantiomer of AMPA that induces apoptosis in cortical neurons

Uses

(S)-AMPA has also been used to activate rostromedial tegmental nucleus (RMTg), to study aversive conditioning in relation with cocaine-induced avoidance behaviors in mice.

Uses

(S)-AMPA is an analogue for AMPA (A611500) a specific agonist for the AMPA receptor which mimics the glutamate receptor.

General Description

AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) activates excitatory postsynaptic currents (EPSC).

Biological Activity

Active enantiomer of AMPA (EC 50 = 3.5 μ M). Also available as part of the AMPA Receptor Tocriset™ .

Biochem/physiol Actions

Active enantiomer of (RS)-AMPA zwitterion. Potent agonist at the AMPA subclass of ionotropic glutamate receptors.

storage

Room temperature

(S)-AMPA Preparation Products And Raw materials

Raw materials

Preparation Products

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83643-88-3, (S)-AMPARelated Search:


  • (S)-A-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID
  • (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID
  • (S)-ALPHA-AMINO-3-HYDROXY-5-METHYLISOXAZOLE-4-PROPIONIC ACID
  • (S)-AMPA
  • (S)-amino-3-hydroxy-5-methylisoxazolepropionic acid
  • (S)-A-amino-3-hydroxy-5-methylisoxazole -4-propio
  • (S)-A-AMINO-3-HYDROXY-5-METHYLISOXAZOLE -4-PROPIONI
  • (s)-α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid
  • (2S)-2-amino-3-(5-methyl-3-oxo-4-isoxazolyl)propanoic acid
  • (S)-alpha-Amino-3-hydroxy-5-methyl-4-isoxazol-propionic acid
  • (2S)-2-Amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid
  • (2S)-2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid
  • (2S)-2-amino-3-(3-keto-5-methyl-isoxazol-4-yl)propionic acid
  • (2S)-2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid
  • (2S)-2-azanyl-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid
  • (S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionicacid
  • (S)-2-aMino-3-(3-hydroxy-5-Methylisoxazol-4-yl)propanoic acid
  • (S)-2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propionic acid
  • AMQ
  • AMQ;GLUTAMATE-AMPA;(S)-A-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID
  • glutamate-AMPA
  • 4-Isoxazolepropanoic acid, α-amino-2,3-dihydro-5-methyl-3-oxo-, (αS)-
  • (S)-2-Amino-3-(5-methyl-3-oxo-2,3-dihydroisoxazol-4-yl)propanoic acid
  • L-AMPA, S-AMPA
  • (S) AMPA,(S)AMPA
  • (S)-AMPA (mM/ml)
  • 83643-88-3
  • C7H10NO5
  • BioChemical
  • Cell Signaling and Neuroscience
  • Cell Biology
  • Ionotropic Glutamate Receptor Modulators
  • Ion Channels
  • Ligand-Gated Ion Channels
  • Glutamate receptor
  • Apoptosis Inducers
  • Glutamate