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(S)-(-)-5-FLUOROWILLARDIINE

Product Name
(S)-(-)-5-FLUOROWILLARDIINE
CAS No.
140187-23-1
Chemical Name
(S)-(-)-5-FLUOROWILLARDIINE
Synonyms
5-fluorowillardiine;(S)-(-)-5-FLUOROWILLARDIINE;3-(5-fluorouracil-1-yl)-L-alanine;(S)-(-)-5-FLUOROWILLARDIINE USP/EP/BP;WILLARDIINE, S(-)-5-FLUORO POTENT AMPA/K AINATE A;(S)-(-)-α-Amino-5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)pyridinepropanoicacid;(αS)-α-Amino-5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid;(αS)-α-Amino-5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid;1(2H)-Pyrimidinepropanoic acid, α-amino-5-fluoro-3,4-dihydro-2,4-dioxo-, (αS)-;(S)-2-amino-3-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propanoic acid
CBNumber
CB7100699
Molecular Formula
C7H8FN3O4
Formula Weight
217.15
MOL File
140187-23-1.mol
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(S)-(-)-5-FLUOROWILLARDIINE Property

Melting point:
>209°C (dec.)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Aqueous Acid (Slightly)
form 
Solid
color 
White to Pale Beige
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
F621728
Product name
(S)-(-)-5-Fluorowillardiine
Packaging
50mg
Price
$620
Updated
2021/12/16
TRC
Product number
F621728
Product name
(S)-(-)-5-Fluorowillardiine
Packaging
10mg
Price
$145
Updated
2021/12/16
ApexBio Technology
Product number
B6251
Product name
(S)-(-)-5-Fluorowillardiine
Packaging
10mg
Price
$229
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0003672
Product name
(S)-(-)-5-FLUOROWILLARDIINE
Purity
95.00%
Packaging
10MG
Price
$716.74
Updated
2021/12/16
ApexBio Technology
Product number
B6251
Product name
(S)-(-)-5-Fluorowillardiine
Packaging
50mg
Price
$929
Updated
2021/12/16
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(S)-(-)-5-FLUOROWILLARDIINE Chemical Properties,Usage,Production

Uses

(S)-(-)-5-Fluorowillardiine is a potent and selective AMPA receptor agonist at hGluR1 and hGluR2 (1,2).

Definition

ChEBI: An alanine derivative that is L-alanine bearing a 5-fluorouracil-1-yl substituent at position 3. A more potent and selective AMPA receptor agonist (at hGluR1 and hGluR2) than AMPA itself (Ki = 14.7, 25.1, and 1820 nM for hGluR1, hGluR2 and hGluR5 respectively).

Biological Activity

A more potent and selective AMPA receptor agonist (at hGluR1 and hGluR2) than AMPA itself (K i = 14.7, 25.1, and 1820 nM for hGluR1, hGluR2 and hGluR5 respectively). Also available as part of the AMPA Receptor Tocriset™ .

(S)-(-)-5-FLUOROWILLARDIINE Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-(-)-5-FLUOROWILLARDIINE Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Ascent Scientific
Tel
4401179829988
Fax
4402030 700 369
Email
customerservice@ascentscientific.co.uk
Country
United Kingdom
ProdList
279
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MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
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58
ShangHai KenEn Chemical Technology Co., Ltd.
Tel
13120367189
Fax
021-50315529
Email
mychess007@163.com
Country
China
ProdList
1994
Advantage
55
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
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60
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
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ShangHai Siyan Biological Technology Co., Ltd.
Tel
021-50908862,442785678,326799392 18721037013
Fax
021-50908862
Email
siyansales@126.com
Country
China
ProdList
9627
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58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29785
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68
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shanghai Kangman Biological Technology Co., Ltd.
Tel
18800375331
Fax
021-50908862
Email
kangmansales@163.com
Country
China
ProdList
7570
Advantage
55
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View Lastest Price from (S)-(-)-5-FLUOROWILLARDIINE manufacturers

Career Henan Chemical Co
Product
(S)-(-)-5-FLUOROWILLARDIINE 140187-23-1
Price
US $1.00/g
Min. Order
100g
Purity
>98%
Supply Ability
g/kg/Ton
Release date
2020-01-14

140187-23-1, (S)-(-)-5-FLUOROWILLARDIINERelated Search:


  • 5-fluorowillardiine
  • (S)-(-)-5-FLUOROWILLARDIINE
  • (S)-(-)-ALPHA-AMINO-5-FLUORO-3,4-DIHYDRO-2,4-DIOXO-1(2H)PYRIDINEPROPANOIC ACID
  • (S)-2-amino-3-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propanoic acid
  • WILLARDIINE, S(-)-5-FLUORO POTENT AMPA/K AINATE A
  • (S)-(-)-alpha-Amino-5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimmidinepropanoic acid
  • (S)-(-)-α-Amino-5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)pyridinepropanoicacid
  • (αS)-α-Amino-5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid
  • 3-(5-fluorouracil-1-yl)-L-alanine
  • 1(2H)-Pyrimidinepropanoic acid, α-amino-5-fluoro-3,4-dihydro-2,4-dioxo-, (αS)-
  • (S)-(-)-5-FLUOROWILLARDIINE USP/EP/BP
  • inhibit,(S)()5Fluorowillardiine,iGluR,(S) ( ) 5 Fluorowillardiine,Ionotropic glutamate receptors,Inhibitor
  • (αS)-α-Amino-5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid
  • 140187-23-1
  • C7H8FN3O4
  • Glutamate receptor
  • Glutamate