ChemicalBook > CAS DataBase List > (S)-(-)-5-FLUOROWILLARDIINE

(S)-(-)-5-FLUOROWILLARDIINE

Product Name
(S)-(-)-5-FLUOROWILLARDIINE
CAS No.
140187-23-1
Chemical Name
(S)-(-)-5-FLUOROWILLARDIINE
Synonyms
5-fluorowillardiine;(S)-(-)-5-FLUOROWILLARDIINE;3-(5-fluorouracil-1-yl)-L-alanine;(S)-(-)-5-FLUOROWILLARDIINE USP/EP/BP;WILLARDIINE, S(-)-5-FLUORO POTENT AMPA/K AINATE A;(S)-(-)-α-Amino-5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)pyridinepropanoicacid;(αS)-α-Amino-5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid;1(2H)-Pyrimidinepropanoic acid, α-amino-5-fluoro-3,4-dihydro-2,4-dioxo-, (αS)-;(S)-2-amino-3-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propanoic acid;(S)-(-)-ALPHA-AMINO-5-FLUORO-3,4-DIHYDRO-2,4-DIOXO-1(2H)PYRIDINEPROPANOIC ACID
CBNumber
CB7100699
Molecular Formula
C7H8FN3O4
Formula Weight
217.15
MOL File
140187-23-1.mol
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(S)-(-)-5-FLUOROWILLARDIINE Property

Melting point:
>209°C (dec.)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Aqueous Acid (Slightly)
form 
Solid
color 
White to Pale Beige
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
F621728
Product name
(S)-(-)-5-Fluorowillardiine
Packaging
10mg
Price
$145
Updated
2021/12/16
TRC
Product number
F621728
Product name
(S)-(-)-5-Fluorowillardiine
Packaging
50mg
Price
$620
Updated
2021/12/16
ApexBio Technology
Product number
B6251
Product name
(S)-(-)-5-Fluorowillardiine
Packaging
10mg
Price
$229
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0003672
Product name
(S)-(-)-5-FLUOROWILLARDIINE
Purity
95.00%
Packaging
10MG
Price
$716.74
Updated
2021/12/16
ApexBio Technology
Product number
B6251
Product name
(S)-(-)-5-Fluorowillardiine
Packaging
50mg
Price
$929
Updated
2021/12/16
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(S)-(-)-5-FLUOROWILLARDIINE Chemical Properties,Usage,Production

Uses

(S)-(-)-5-Fluorowillardiine is a potent and selective AMPA receptor agonist at hGluR1 and hGluR2 (1,2).

Definition

ChEBI: An alanine derivative that is L-alanine bearing a 5-fluorouracil-1-yl substituent at position 3. A more potent and selective AMPA receptor agonist (at hGluR1 and hGluR2) than AMPA itself (Ki = 14.7, 25.1, and 1820 nM for hGluR1, hGluR2 and hGluR5 respectively).

Biological Activity

A more potent and selective AMPA receptor agonist (at hGluR1 and hGluR2) than AMPA itself (K i = 14.7, 25.1, and 1820 nM for hGluR1, hGluR2 and hGluR5 respectively). Also available as part of the AMPA Receptor Tocriset™ .

(S)-(-)-5-FLUOROWILLARDIINE Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-(-)-5-FLUOROWILLARDIINE Suppliers

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View Lastest Price from (S)-(-)-5-FLUOROWILLARDIINE manufacturers

Career Henan Chemical Co
Product
(S)-(-)-5-FLUOROWILLARDIINE 140187-23-1
Price
US $1.00/g
Min. Order
100g
Purity
>98%
Supply Ability
g/kg/Ton
Release date
2020-01-14

140187-23-1, (S)-(-)-5-FLUOROWILLARDIINERelated Search:

5-Bromouracil Alkaline Phosphatase Phenprobamate EC 2.6.1.2 5-Fluorouracil Albizziin L-2,3-Diaminopropionic acid 3-(N-Methylamino)-L-alanine (2S)-2-Amino-3-dimethylaminopropanoic acid S(-)-ALPHA-AMINO-3,4-DIHYDRO-2,4-DIOXO-1(2H)-PYRIMIDINEPROPANOIC ACID (S)-5-FLUOROWILLARDIINE, [3H] (3H)-(S)-5-FLUOROWILLARDIINE azaleucine 2-AMINO-3-(2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID 3-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)propanoic acid (S)-(-)-5-FLUOROWILLARDIINE

  • 5-fluorowillardiine
  • (S)-(-)-5-FLUOROWILLARDIINE
  • (S)-(-)-ALPHA-AMINO-5-FLUORO-3,4-DIHYDRO-2,4-DIOXO-1(2H)PYRIDINEPROPANOIC ACID
  • (S)-2-amino-3-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propanoic acid
  • WILLARDIINE, S(-)-5-FLUORO POTENT AMPA/K AINATE A
  • (S)-(-)-alpha-Amino-5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimmidinepropanoic acid
  • (S)-(-)-α-Amino-5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)pyridinepropanoicacid
  • (αS)-α-Amino-5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid
  • 3-(5-fluorouracil-1-yl)-L-alanine
  • 1(2H)-Pyrimidinepropanoic acid, α-amino-5-fluoro-3,4-dihydro-2,4-dioxo-, (αS)-
  • (S)-(-)-5-FLUOROWILLARDIINE USP/EP/BP
  • inhibit,(S)()5Fluorowillardiine,iGluR,(S) ( ) 5 Fluorowillardiine,Ionotropic glutamate receptors,Inhibitor
  • 140187-23-1
  • C7H8FN3O4
  • Glutamate receptor
  • Glutamate