ChemicalBook > CAS DataBase List > CNQX
CNQX
- Product Name
- CNQX
- CAS No.
- 115066-14-3
- Chemical Name
- CNQX
- Synonyms
- CNQX;CNOX;FG-9065;CNQX 2NA;CNQX DISODIUM;CNQX DISODIUM SALT;CNQX disodium salt hydrate;CNQX DISODIUM KAINATE/AMPA RECEPTOR;CNQX (FG-9065) (6-CYANO-7-NITROQUINO;6-Nitro-7-cyanoquinoxaline-2,3-dione
- CBNumber
- CB0728641
- Molecular Formula
- C9H4N4O4
- Formula Weight
- 232.15
- MOL File
- 115066-14-3.mol
More
Less
CNQX Property
- Melting point:
- 300 °C
- Boiling point:
- 374.31°C (rough estimate)
- Density
- 1.5507 (rough estimate)
- refractive index
- 1.6590 (estimate)
- RTECS
- VD1520000
- storage temp.
- protect from light
- solubility
- H2O: 10 mg/mL
- form
- solid
- pka
- 8.16±0.20(Predicted)
- color
- orange to red
- Stability:
- Store Tightly Sealed at RT
- CAS DataBase Reference
- 115066-14-3(CAS DataBase Reference)
More
Less
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
More
Less
N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- C127
- Product name
- CNQX
- Purity
- ≥98% (HPLC), solid
- Packaging
- 5mg
- Price
- $162
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- C127
- Product name
- CNQX
- Purity
- ≥98% (HPLC), solid
- Packaging
- 25mg
- Price
- $546
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 5.04914
- Product name
- CNQX - CAS 115066-14-3 - Calbiochem
- Packaging
- 10mg
- Price
- $176
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- J63472
- Product name
- 6-Cyano-7-nitro-1,4-dihydroquinoxaline-2,3-dione, 98%
- Packaging
- 10mg
- Price
- $133.65
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- J63472
- Product name
- 6-Cyano-7-nitro-1,4-dihydroquinoxaline-2,3-dione, 98%
- Packaging
- 25mg
- Price
- $349.65
- Updated
- 2024/03/01
More
Less
CNQX Chemical Properties,Usage,Production
Chemical Properties
Pale Yellow Solid
Uses
CNQX disodium salt hydrate has been used as:
- as a competitive non-NMDA receptor antagonist and competitive AMPA/kainate receptor antagonist in neuronal cultures(110)
- as a glutamatergic blockers for measuring inhibitory postsynaptic currents in projection neurons(111)
- as a AMPA glutamate receptor antagonist prefrontal cortex neurons(112)
Uses
A potent, competitive kainate/quisqualate (non-NMDA) receptor antagonist. IC50 of tritiated ligands to rat cortical membranes by CNQX: AMPA, Kainate and CPP are 0.3mM, 1.5mM, and 25mM, respectively
Uses
CNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively, versus IC50 = 25 μM for NMDA receptors). This compound has been used to specifically target AMPA and kainate receptor responses and thus differentiate from that of NMDA receptors.
Definition
ChEBI: 6-Cyano-7-nitroquinoxaline-2,3-dione is a quinoxaline derivative.
Biological Activity
Potent AMPA/kainate receptor antagonist. Also antagonist at glycine modulatory site on NMDA receptor complex.
Biochem/physiol Actions
Potent, competitive AMPA/kainate glutamate receptor antagonist.
storage
Room temperature
CNQX Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
CNQX Suppliers
- Tel
- 010-82848833 400-666-7788
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006608290; 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40241
- Advantage
- 62
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15848
- Advantage
- 69
- Tel
- 4401179829988
- Fax
- 4402030 700 369
- customerservice@ascentscientific.co.uk
- Country
- United Kingdom
- ProdList
- 279
- Advantage
- 60
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- zhangsn@titansci.com
- Country
- China
- ProdList
- 14113
- Advantage
- 59
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 32344
- Advantage
- 50
- Tel
- 0411-62910999 13889544652
- sales@meilune.com
- Country
- China
- ProdList
- 4647
- Advantage
- 58
- Tel
- 800-810-5118
- Fax
- +86-10-84193589
- cnchemical@thermofisher.com
- Country
- China
- ProdList
- 17779
- Advantage
- 75
- Tel
- 18521735133 18521732826;
- Fax
- 021-50323701
- market@aladdin-e.com
- Country
- China
- ProdList
- 25015
- Advantage
- 65
- Tel
- 021-58955995
- Fax
- 609-228-5909
- sales@medchemexpress.cn
- Country
- United States
- ProdList
- 4863
- Advantage
- 58
More
Less
View Lastest Price from CNQX manufacturers
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- 6-CYANO-7-NITROQUINOXALINE-2,3-DIONE 115066-14-3
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
115066-14-3, CNQXRelated Search:
2-Nitrobenzonitrile
N,N'-Dimethyloxalamide
2-HYDROXY-6-METHYLQUINOXALINE
3-Methyl-4-nitroaniline
1,2,3,4-TETRAHYDRO-QUINOXALINE
4-ACETAMIDOBENZONITRILE
2,3-DIHYDROXYQUINOXALINE
3,4-Diaminobenzonitrile
4-ACETAMIDO-2-METHYLNITROBENZENE
6-NITROQUINOXALINE-2,3-DIONE
2,5-Diaminobenzonitrile
1,4-DIHYDRO-6-METHYLQUINOXALINE-2,3-DIONE
6-NITRO-1,2,3,4-TETRAHYDRO QUINOXALINE
4-(N-Methylamino)benzonitrile
CNQX
N'-METHYL-4-NITROPHENYLENEDIAMINE-(1,2)
PYRAZINE-2,3-DIOL
N-(4-amino-3-methylphenyl)acetamide