CNQX
- Product Name
- CNQX
- CAS No.
- 115066-14-3
- Chemical Name
- CNQX
- Synonyms
- CNQX;CNOX;FG-9065;CNQX 2NA;CNQX DISODIUM;CNQX DISODIUM SALT;CNQX disodium salt hydrate;CNQX DISODIUM KAINATE/AMPA RECEPTOR;CNQX (FG-9065) (6-CYANO-7-NITROQUINO;6-Nitro-7-cyanoquinoxaline-2,3-dione
- CBNumber
- CB0728641
- Molecular Formula
- C9H4N4O4
- Formula Weight
- 232.15
- MOL File
- 115066-14-3.mol
CNQX Property
- Melting point:
- 300 °C
- Boiling point:
- 374.31°C (rough estimate)
- Density
- 1.5507 (rough estimate)
- refractive index
- 1.6590 (estimate)
- RTECS
- VD1520000
- storage temp.
- protect from light
- solubility
- H2O: 10 mg/mL
- form
- solid
- pka
- 8.16±0.20(Predicted)
- color
- orange to red
- Stability:
- Store Tightly Sealed at RT
- CAS DataBase Reference
- 115066-14-3(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- C127
- Product name
- CNQX
- Purity
- ≥98% (HPLC), solid
- Packaging
- 5mg
- Price
- $162
- Updated
- 2024/03/01
- Product number
- C127
- Product name
- CNQX
- Purity
- ≥98% (HPLC), solid
- Packaging
- 25mg
- Price
- $546
- Updated
- 2024/03/01
- Product number
- 5.04914
- Product name
- CNQX - CAS 115066-14-3 - Calbiochem
- Packaging
- 10mg
- Price
- $176
- Updated
- 2024/03/01
- Product number
- J63472
- Product name
- 6-Cyano-7-nitro-1,4-dihydroquinoxaline-2,3-dione, 98%
- Packaging
- 10mg
- Price
- $133.65
- Updated
- 2024/03/01
- Product number
- J63472
- Product name
- 6-Cyano-7-nitro-1,4-dihydroquinoxaline-2,3-dione, 98%
- Packaging
- 25mg
- Price
- $349.65
- Updated
- 2024/03/01
CNQX Chemical Properties,Usage,Production
Chemical Properties
Pale Yellow Solid
Uses
CNQX disodium salt hydrate has been used as:
- as a competitive non-NMDA receptor antagonist and competitive AMPA/kainate receptor antagonist in neuronal cultures(110)
- as a glutamatergic blockers for measuring inhibitory postsynaptic currents in projection neurons(111)
- as a AMPA glutamate receptor antagonist prefrontal cortex neurons(112)
Uses
A potent, competitive kainate/quisqualate (non-NMDA) receptor antagonist. IC50 of tritiated ligands to rat cortical membranes by CNQX: AMPA, Kainate and CPP are 0.3mM, 1.5mM, and 25mM, respectively
Uses
CNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively, versus IC50 = 25 μM for NMDA receptors). This compound has been used to specifically target AMPA and kainate receptor responses and thus differentiate from that of NMDA receptors.
Definition
ChEBI: 6-Cyano-7-nitroquinoxaline-2,3-dione is a quinoxaline derivative.
Biological Activity
Potent AMPA/kainate receptor antagonist. Also antagonist at glycine modulatory site on NMDA receptor complex.
Biochem/physiol Actions
Potent, competitive AMPA/kainate glutamate receptor antagonist.
storage
Room temperature
CNQX Preparation Products And Raw materials
Raw materials
Preparation Products
View Lastest Price from CNQX manufacturers
- Product
- 6-CYANO-7-NITROQUINOXALINE-2,3-DIONE 115066-14-3
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11