4-Hydroxy-3-methoxybenzylamine hydrochloride
- Product Name
- 4-Hydroxy-3-methoxybenzylamine hydrochloride
- CAS No.
- 7149-10-2
- Chemical Name
- 4-Hydroxy-3-methoxybenzylamine hydrochloride
- Synonyms
- VANILLYLAMINE HCL;)-2-methoxyphenoL;TIMTEC-BB SBB003667;Vanillin hydrochloride;vanillylammonium chloride;Vanilylamine hydrochloride;Vanillyamine hydrochloride;VANILLYLAMINE HYDROCHLORIDE;4-AMINOMETHYL-2-METHOXYPHENO;α-Aminocreosol Hydrochloride
- CBNumber
- CB6722621
- Molecular Formula
- C8H12ClNO2
- Formula Weight
- 189.64
- MOL File
- 7149-10-2.mol
4-Hydroxy-3-methoxybenzylamine hydrochloride Property
- Melting point:
- 219-221 °C (dec.)(lit.)
- storage temp.
- Store below +30°C.
- solubility
- DMSO (Slightly, Heated), Methanol (Slightly)
- form
- Powder
- color
- Off-white
- Sensitive
- Moisture Sensitive
- BRN
- 3915418
- Stability:
- Hygroscopic
- InChI
- InChI=1S/C8H11NO2.ClH/c1-11-8-4-6(5-9)2-3-7(8)10;/h2-4,10H,5,9H2,1H3;1H
- InChIKey
- PUDMGOSXPCMUJZ-UHFFFAOYSA-N
- SMILES
- C1(OC)=C(O)C=CC(CN)=C1.Cl
- LogP
- 5.4 at 30℃
- CAS DataBase Reference
- 7149-10-2(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-37/39-36
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29214990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- H36605
- Product name
- 4-Hydroxy-3-methoxybenzylamine hydrochloride
- Purity
- 98%
- Packaging
- 1g
- Price
- $46.5
- Updated
- 2025/07/31
- Product number
- 8.41494
- Product name
- 4-Hydroxy-3-methoxybenzylamine hydrochloride
- Purity
- for synthesis
- Packaging
- 1G
- Price
- $43.8
- Updated
- 2023/01/07
- Product number
- A2330
- Product name
- 4-(Aminomethyl)-2-methoxyphenol Hydrochloride
- Purity
- >98.0%(HPLC)(N)
- Packaging
- 5g
- Price
- $31
- Updated
- 2025/07/31
- Product number
- A2330
- Product name
- 4-(Aminomethyl)-2-methoxyphenol Hydrochloride
- Purity
- >98.0%(HPLC)(N)
- Packaging
- 25g
- Price
- $99
- Updated
- 2025/07/31
- Product number
- 022736
- Product name
- Vanillylamine Hydrochloride
- Packaging
- 5g
- Price
- $425
- Updated
- 2021/12/16
4-Hydroxy-3-methoxybenzylamine hydrochloride Chemical Properties,Usage,Production
Chemical Properties
white to light yellow crystal powde
Uses
A metabolite of Capsaicin.
Synthesis
2874-33-1
7149-10-2
The preparation method of the present invention for the preparation of vanillin amine hydrochloride is described in detail in the following steps: A, 4-hydroxy-3-methoxybenzaldehyde oxime was used as raw material, and ethanol was used as solvent; firstly, 133.6 g (0.80 mol) of 4-hydroxy-3-methoxybenzaldehyde oxime was added into a 2L three-necked flask fitted with a stirrer and a thermometer, and then 1,400mL of ethanol and 13.0 g of an aluminum-zinc Nickel composite catalyst, under the condition of passing hydrogen for protection, heating to 40°C, the reaction for 8 hours; B, after the completion of the reaction filtration (the filtrate residue is the unreacted catalyst, can be recycled), in the filtrate add 70mL of hydrochloric acid with a mass concentration of 30%, adjusting the filtrate pH to 1, precipitated white crystals, filtration to isolate the white crystals, drying in vacuum, to obtain vanillin amine hydrochloride 136.8 g, yield 90.5%.
References
[1] Polymer, 2011, vol. 52, # 9, p. 1908 - 1916
[2] Journal of Organic Chemistry, 1988, vol. 53, # 5, p. 1064 - 1071
[3] Patent: CN106366004, 2017, A. Location in patent: Paragraph 0017-0028
[4] Patent: JP2005/527478, 2005, A. Location in patent: Page/Page column 4
[5] Russian Chemical Bulletin, 2018, vol. 67, # 8, p. 1394 - 1400
4-Hydroxy-3-methoxybenzylamine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
4-Hydroxy-3-methoxybenzylamine hydrochloride Suppliers
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- Country
- Belgium
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View Lastest Price from 4-Hydroxy-3-methoxybenzylamine hydrochloride manufacturers
- Product
- 4-Hydroxy-3-methoxybenzylamine hydrochloride 7149-10-2
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-21
- Product
- VanillylaMine hydrochloride 7149-10-2
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-30
- Product
- 4-Hydroxy-3-methoxybenzylamine hydrochloride 7149-10-2
- Price
- US $5.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2024-08-22