ChemicalBook > CAS DataBase List > DL-Octopamine hydrochloride

DL-Octopamine hydrochloride

Product Name
DL-Octopamine hydrochloride
CAS No.
770-05-8
Chemical Name
DL-Octopamine hydrochloride
Synonyms
OCTOPAMINE HCL;OCTOPAMINE HYDROCHLORIDE;dl-octopamine;OCTAPAMINE HCL;OCTOPAMINE HCL(P);OCTOPAMINE HCL(RG);DL-Octopaminehydroc;(+,-)-Octopamine HCl;OctopaMine HCl 99%Min;Chapter hydrochloride
CBNumber
CB8778718
Molecular Formula
C8H12ClNO2
Formula Weight
189.64
MOL File
770-05-8.mol
More
Less

DL-Octopamine hydrochloride Property

Melting point:
~170 °C (dec.)(lit.)
Boiling point:
290℃[at 101 325 Pa]
Density 
1.39[at 20℃]
vapor pressure 
0.002Pa at 20℃
storage temp. 
2-8°C
solubility 
H2O: soluble
form 
solid
color 
white or off-white
Water Solubility 
soluble
Merck 
13,6791
BRN 
3915414
Stability:
Stable.
LogP
-2.6 at 20.1℃
CAS DataBase Reference
770-05-8(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
36-37/39-26
RIDADR 
3249
WGK Germany 
3
HazardClass 
6.1(b)
PackingGroup 
III
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
O0250
Product name
(±)-Octopamine hydrochloride
Purity
≥95%, solid
Packaging
1g
Price
$60.9
Updated
2024/03/01
Sigma-Aldrich
Product number
68631
Product name
(±)-Octopamine hydrochloride
Purity
analytical standard
Packaging
100mg
Price
$70.8
Updated
2024/03/01
Alfa Aesar
Product number
J61281
Product name
(±)-Octopamine hydrochloride, 99%
Packaging
1g
Price
$30.65
Updated
2024/03/01
Alfa Aesar
Product number
J61281
Product name
(±)-Octopamine hydrochloride, 99%
Packaging
5g
Price
$72.65
Updated
2024/03/01
Cayman Chemical
Product number
14279
Product name
(±)-para-Octopamine (hydrochloride)
Purity
≥98%
Packaging
1g
Price
$32
Updated
2024/03/01
More
Less

DL-Octopamine hydrochloride Chemical Properties,Usage,Production

Chemical Properties

DL-Octopamine hydrochloride is a light-yellow crystalline solid and derived from the dried young fruit of Citrus aurantium L., a plant of the Rutaceae family,It is soluble to 10 mg/ml in PBS, 10 mg/ml in EtOH, and 12 mg/ml in DMSO & DMF. Its use is similar to that of Synflorin HCL. It is an adrenergic alpha-receptor stimulant with vasoconstrictive and hypertensive effects.

Originator

Norfen,Morishita, Japan ,1975

Uses

Octopamine HCL has the ability to halt catabolism of proteinaceous tissues. It is very important while losing weight to maximize adipose loss while minimizing the loss of muscle and other lean body tissue. Octopamine Hcl (norepinephrine) is best known as an effective ephedrine alternative, claiming to boost energy while reduce weight in bodybuilding industry for weight loss purpose. In addition, many users believe octopamine hcl is a good nootropic compound that makes our brain easy to focus, enhances motivation as a wakefulness promoter.

Uses

A biogenic amine that is the phenol analog of Noradrenaline. It is a neurosecretory product found in several vertebrates and invertebrates. Adrenergic.

Manufacturing Process

A solution of 33 grams of anhydrous aluminum chloride in 60 grams of nitrobenzene, to which a mixture of 14 grams of phenol and 9.3 grams of hydrochloride of amino-acetonitrile was added, had dry hydrochloric acid gas introduced into it for 3 hours, while stirring and cooling to keep the temperature between 20° and 30°C. The reaction mixture was then poured, with cooling, into 70 cc of water and the deposit obtained was sucked off, washed with acetone and dissolved in 300 cc of water. The solution thus prepared was decolorized with carbon, 50 grams of 30% sodium citrate solution was added to it, and then it was made slightly alkaline with ammonia. Thereupon hydroxy-4'-phenyl-1-amino-2-ethanone crystallized out in the form of leaflets. The yield was 7.7 grams.
The hydrochloride of this base, obtained by evaporation to dryness of a solution of the base in dilute hydrochloric acid and subsequent treatment of the residue with ethyl alcohol and acetone, had a chlorine content of 18.84%, (calculated, 18.90%).
This hydrochloride, on being dissolved in water and hydrogenated with hydrogen and a nickel catalyst, gave a good yield of hydrochloride of hydroxy4'-phenyl-1-amino-2-ethanol melting, after crystallization from a mixture of ethyl alcohol and butanone-2, at from 177° to 179°C with decomposition

Therapeutic Function

Hypertensive

General Description

Octopamine is a biogenic amine, which functions as a neurotransmitter, neuromodulator and neurohormone. It is used to regulate various behaviors, such as learning, memory and aggression. Octopamine is present in mammalian tissues, human urine and invertebrates.

Flammability and Explosibility

Not classified

Biological Activity

Invertebrate biogenic amine neurotransmitter, related to noradrenalin, that is an adrenoceptor agonist. Stimulates lipolysis in mammalian adipocytes via activation of β 3 receptors. Has dual effect on glucose transport in adipocytes: inhibits transport via β 3 receptor activation but stimulates transport when oxidised by MAO. Also activates human α 2A receptors, inhibiting subsequent cAMP production.

Mode of action

Octopamine hydrochloride is an invertebrate biogenic amine neurotransmitter, related to noradrenalin, that is an adrenoceptor (AR) agonist. Octopamine hydrochloride stimulates lipolysis in mammalian adipocytes via activation of β3-AR receptors. Has dual effect on glucose transport in adipocytes: inhibits transport via β3-AR receptor activation but stimulates transport when oxidised by MAO. Also activates human α2A-AR receptors, inhibiting subsequent cAMP production.

DL-Octopamine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

DL-Octopamine hydrochloride Suppliers

PharmSyn CO.,LTD
Tel
0512-65218020 18261037325
Email
biz@pharmsyn.com
Country
China
ProdList
75
Advantage
60
Jiangsu Huayu Chemical Co., Ltd.
Tel
25-83241163
Fax
+86-25-83241173
Email
sales@elegantnutri.com
Country
China
ProdList
55
Advantage
55
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3576
Advantage
66
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1998
Advantage
65
Ark Pharm, Inc.
Tel
847-367-3680
Fax
847-367-3681
Email
sales@arkpharminc.com
Country
United States
ProdList
1670
Advantage
56
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9552
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11660
Advantage
64
More
Less

View Lastest Price from DL-Octopamine hydrochloride manufacturers

BINBO BIOLOGICAL CO.,LTD
Product
Octopamine hydrochloride 770-05-8
Price
US $0.00/kg
Min. Order
1kg
Purity
>98%
Supply Ability
1000 kg
Release date
2024-04-09
Hebei Yanxi Chemical Co., Ltd.
Product
Octopamine HCl 770-05-8
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20tons
Release date
2023-10-17
Hebei Yanxi Chemical Co., Ltd.
Product
Octopamine HCl 770-05-8
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20tons
Release date
2023-10-17

770-05-8, DL-Octopamine hydrochloride Related Search:


  • dl-octopamine
  • alpha-(Aminomethyl)-p-hydroxybenzylic alcohol hydrochloride
  • DL-Octopamine hydrochloride,98+%
  • (±)-Octopamine hydrochloride,α-(Aminomethyl)-4-hydroxybenzyl alcohol hydrochloride, (±)-1-(4-Hydroxyphenyl)-2-amino-ethanol hydrochloride
  • (+/-)-p-OctopaMaine-Hydrochloride
  • (+)p-octopaMine hydrochloride
  • (±)-p-OctopaMine-a,,-d3 HCl
  • (±)-para-Octopamine (hydrochloride)
  • (±)-1-(4-Hydroxyphenyl)-2-amino
  • DL-Octopamine hydrochloride≥ 99% (HPLC,anhydrous basis)
  • OctopaMine HCl 99%Min
  • ChapteraMine hydrochloride
  • Chapter hydrochloride
  • OctopaMinehydrochlorid
  • Benzenemethanol, .alpha.-(aminomethyl)-4-hydroxy-, hydrochloride, (.+-.)-
  • Benzyl alcohol, .alpha.-(aminomethyl)-p-hydroxy-, hydrochloride, (.+-.)-
  • dl-Epirenor hydrochlor
  • (±)-p-Octopamine hydrochlorid
  • DL-OCTOPAMINE HYDROCHLORIDE
  • DL-1-(4-HYDROXYPHENYL)-2-AMINOETHANOL HYDROCHLORIDE
  • dl-alpha-(aminomethyl)-4-hydroxybenzyl alcohol hydrochloride
  • DL-A-(AMINOMETHYL)-P-HYDROXYBENZYL ALCOHOL HYDROCHLORIDE
  • 1-[P-HYDROXYPHENYL]-2-AMINOETHANOL HCL
  • 1-[P-HYDROXYPHENYL]-2-AMINOETHANOL HYDROCHLORIDE
  • (+/-)-1-(4-HYDROXYPHENYL)-2-AMINOETHANOL HYDROCHLORIDE
  • OCTAPAMINE HCL
  • OCTOPAMINE HCL
  • (+/-)-OCTOPAMINE HYDROCHLORIDE
  • OCTOPAMINE HYDROCHLORIDE
  • P-(+/-)-ALPHA-(AMINOMETHYL)HYDROXYBENZYL ALCOHOL, HCL
  • P-HYDROXYPHENYLAMINOETHANOL HYDROCHLORIDE
  • ALPHA-(AMINOMETHYL)-4-HYDROXYBENZENEMETHANOL HYDROCHLORIDE
  • DL-alpha-(aminomethyl)-p-hydroxybenzylic alcohol hydrochloride
  • Octopamine(Norsynephrine)
  • DL-Octapamine hydrochloride.
  • OCTOPAMINE HCL(P)
  • OCTOPAMINE HCL(RG)
  • Octopamine hydrochloride 99.0%min
  • α-(Aminomethyl)-4-hydroxybenzyl alcohol hydrochloride, (±)-1-(4-Hydroxyphenyl)-2-aminoethanol hydrochloride
  • 4-(2-Amino-1-hydroxyethyl)phenol hydrochloride
  • DL-Octopaminehydroc
  • (+,-)-Octopamine HCl
  • alpha-(Aminomethyl)-4-hydroxybenzyl Alcohol Hydrochloride
  • DL-Octopamine hydrochloride USP/EP/BP
  • (+/-)-Octopamine hydrochloride analytical standard, ≥98%
  • 770-05-8
  • C8H11NO2xHCl
  • C8H11NO2HClC8H12ClNO2
  • alpha-adrenoceptor agonist; invertebrate neurotransmitter.
  • Building Blocks
  • Amino Alcohols
  • Oxygen Compounds
  • Organic Building Blocks
  • Pharma raw material
  • Amines
  • Aromatics
  • Neurochemicals
  • Miscellaneous Natural Products