Octopamine
- Product Name
- Octopamine
- CAS No.
- 104-14-3
- Chemical Name
- Octopamine
- Synonyms
- p-Octopamine;Norden;OctopaMine-d3;ND-50;ND 50;C04227;Analet;Norfen;Norphen;OCTOPAMINE
- CBNumber
- CB8482020
- Molecular Formula
- C8H11NO2
- Formula Weight
- 153.18
- MOL File
- 104-14-3.mol
Octopamine Property
- Melting point:
- 157-158 °C
- Boiling point:
- 276.1°C (rough estimate)
- Density
- 1.1577 (rough estimate)
- refractive index
- 1.5010 (estimate)
- pka
- pKa 8.88 (Uncertain);9.53 (Uncertain)
- CAS DataBase Reference
- 104-14-3(CAS DataBase Reference)
Safety
- RIDADR
- 3249
- HazardClass
- 6.1(b)
- PackingGroup
- III
- Toxicity
- LD50 oral in rat: 1240mg/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P322Specific measures (see …on this label).
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 461480
- Product name
- Octopamine
- Packaging
- 250mg
- Price
- $496
- Updated
- 2021/12/16
- Product number
- API0008679
- Product name
- DL-OCTOPAMINE
- Purity
- 95.00%
- Packaging
- 0.5G
- Price
- $271
- Updated
- 2021/12/16
- Product number
- MT-39562
- Product name
- 4-(2-Amino-1-hydroxy-ethyl)phenol
- Purity
- 98%
- Packaging
- 1000g
- Price
- $680
- Updated
- 2021/12/16
Octopamine Chemical Properties,Usage,Production
Description
An alkaloid found in annual rye grass, this base has been suggested as a possible precursor of annuloline (q.v.).
Originator
Norfen,Morishita, Japan ,1975
Uses
Octopamine is a biogenic monoamine structurally related to Noradrenaline (N661038), it acts as a neurohormone, neuromodulator and a neurotransmitter in invertebrates.
Definition
ChEBI: Octopamine is a member of the class of phenylethanolamines that is phenol which is substituted at the para- position by a 2-amino-1-hydroxyethyl group. A biogenic phenylethanolamine which has been found to act as a neurotransmitter, neurohormone or neuromodulator in invertebrates. It has a role as a neurotransmitter. It is a member of phenylethanolamines and a member of tyramines. It is a conjugate base of an octopaminium.
Manufacturing Process
A solution of 33 grams of anhydrous aluminum chloride in 60 grams of nitrobenzene, to which a mixture of 14 grams of phenol and 9.3 grams of hydrochloride of amino-acetonitrile was added, had dry hydrochloric acid gas introduced into it for 3 hours, while stirring and cooling to keep the temperature between 20° and 30°C. The reaction mixture was then poured, with cooling, into 70 cc of water and the deposit obtained was sucked off, washed with acetone and dissolved in 300 cc of water. The solution thus prepared was decolorized with carbon, 50 grams of 30% sodium citrate solution was added to it, and then it was made slightly alkaline with ammonia. Thereupon hydroxy-4'-phenyl-1-amino-2-ethanone crystallized out in the form of leaflets. The yield was 7.7 grams.
The hydrochloride of this base, obtained by evaporation to dryness of a solution of the base in dilute hydrochloric acid and subsequent treatment of the residue with ethyl alcohol and acetone, had a chlorine content of 18.84%, (calculated, 18.90%).
This hydrochloride, on being dissolved in water and hydrogenated with hydrogen and a nickel catalyst, gave a good yield of hydrochloride of hydroxy4'-phenyl-1-amino-2-ethanol melting, after crystallization from a mixture of ethyl alcohol and butanone-2, at from 177° to 179°C with decomposition
Therapeutic Function
Hypertensive
References
Hardwick, Axelrod, Plant Physiol., 44, 1745 (1969)
Octopamine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Octopamine manufacturers
- Product
- Octopamine 104-14-3
- Price
- US $100.00/bag
- Min. Order
- 1bag
- Purity
- 99
- Supply Ability
- 5000
- Release date
- 2023-09-11
- Product
- Octopamine 104-14-3
- Price
- US $150.00/kg
- Min. Order
- 1kg
- Purity
- 99.9%
- Supply Ability
- 10000MT
- Release date
- 2023-06-09
- Product
- Octopamine 104-14-3
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-02-11