ChemicalBook > CAS DataBase List > 4-tert-Octylphenol

4-tert-Octylphenol

Product Name
4-tert-Octylphenol
CAS No.
140-66-9
Chemical Name
4-tert-Octylphenol
Synonyms
Phenol, 4-(1,1,3,3-tetramethylbutyl)-;PTOP;4-(1,1,3,3-TETRAMETHYLBUTYL)PHENOL;PARA-TERT-OCTYLPHENOL;p-octylphenol;P-T-OCTYL PHENOL;NSC 5427;NSC 7248;p-(tert-octyL;4-t-Octylphenol
CBNumber
CB6724049
Molecular Formula
C14H22O
Formula Weight
206.32
MOL File
140-66-9.mol
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4-tert-Octylphenol Property

Melting point:
79-82 °C(lit.)
Boiling point:
175 °C30 mm Hg(lit.)
Density 
0.95 g/cm3 (20℃)
vapor pressure 
2Pa at 38℃
refractive index 
1.5003 (estimate)
Flash point:
145 °C
storage temp. 
-20°C
solubility 
water: slightly soluble0.007g/L at 20°C
pka
10.15±0.15(Predicted)
form 
Solid
color 
White flakes
PH Range
6 at 10 g/l at 20 °C
Water Solubility 
7mg/L at 20℃
BRN 
513992
Stability:
Stable. Incompatible with strong oxidizing agents, strong bases.
LogP
4.8 at 22℃
CAS DataBase Reference
140-66-9(CAS DataBase Reference)
NIST Chemistry Reference
Phenol, 4-(1,1,3,3-tetramethylbutyl)-(140-66-9)
EPA Substance Registry System
p-(1,1,3,3-Tetramethylbutyl)phenol (140-66-9)
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Safety

Hazard Codes 
Xn,N,Xi,F
Risk Statements 
21-38-41-50/53-67-66-36-11-52/53-68-62-40
Safety Statements 
26-36-61-60-39-16-9
RIDADR 
2430
WGK Germany 
2
RTECS 
SM9625000
HazardClass 
8
PackingGroup 
III
HS Code 
29071300
Hazardous Substances Data
140-66-9(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
442858
Product name
4-tert-Octylphenol
Purity
analytical standard
Packaging
500mg
Price
$52.6
Updated
2024/03/01
Sigma-Aldrich
Product number
290823
Product name
4-tert-Octylphenol
Purity
97%
Packaging
25g
Price
$52.8
Updated
2024/03/01
Sigma-Aldrich
Product number
290823
Product name
4-tert-Octylphenol
Purity
97%
Packaging
1kg
Price
$208
Updated
2024/03/01
TCI Chemical
Product number
T0144
Product name
4-(1,1,3,3-Tetramethylbutyl)phenol
Purity
>95.0%(GC)
Packaging
25g
Price
$23
Updated
2024/03/01
TCI Chemical
Product number
T0144
Product name
4-(1,1,3,3-Tetramethylbutyl)phenol
Purity
>95.0%(GC)
Packaging
500g
Price
$41
Updated
2024/03/01
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4-tert-Octylphenol Chemical Properties,Usage,Production

Chemical Properties

white powder

Uses

4-tert-Octylphenol (4t-OP) is used in manufacturing processes as an intermediate in the generation of surfactants, synthetic rubber additives, or resins. 4t-OP is also used to manufacture alkylphenol ethoxylates. It is found mainly in detergents, cleaning products, and emulsifiers and less frequently in paints, personal care products, pesticides, paper, pulp, and textiles.

Definition

ChEBI: 4-tert-Octylphenol is an alkylbenzene.

General Description

4-tert-Octylphenol is a potential environmental pollutant and it exhibits toxic and estrogenic effects on mammalian cells. It binds to estrogen receptors and exerts estrogenic actions in vitro. The transformation of the 4-tert-octylphenol upon irradiation at 253.7nm and by hydroxyl radicals generated by the photolysis (λexc = 253.7nm) of hydrogen peroxide in aqueous solution has been studied.

Health effects

4-tert-octylphenol (OP) is an endocrine-disrupting chemical that causes harmful effects to human health.a common environmental pollutant showing weak estrogenic effects. 4-tert-Octylphenol has been shown to cause harm to the male reproductive system of vertebrates.
High doses of several alkylphenols, including 4- tert-octylphenol, have altered estrogenic effects, including sex hormone levels, estrus cycles, reproductive outcomes, neonatal sexual development, as well as impaired production of steroid hormone and testicular atrophy.

Environmental Fate

Studies have shown that 4t-OP will adsorb to sediments.

Purification Methods

Crystallise the phenol from n-hexane and/or distil it in a vacuum. [Beilstein 6 III 2051, 6 IV 3484.]

Toxicity evaluation

4t-OP has been shown to be an estrogen receptor (ER) agonist. Estrogenic effects of 4t-OP have been demonstrated in human cells, with 4t-OP displacing the natural estrogen 17b estradiol from its receptor, and 4t-OP inducing cell proliferation in estrogen-dependent cell proliferation assays. In vivo confirmation of 4t-OP’s estrogenicity has been confirmed with the uterotrophic assay.

4-tert-Octylphenol Preparation Products And Raw materials

Raw materials

Phenol Polyisobutylene 2,4,4-TRIMETHYL-2-PENTENE

Preparation Products

octyl phenyl polyoxyethylene (30) ether emulsifier SOPE-6 POLYETHYLENE GLYCOL TERT-OCTYLPHENYL ETHER pesticide emulsifier 700^<#^> emulsifier SOPE-4 emulsifier SOPE-7 emulsifier SOPE-20 Bromoxynil emulsifier SOPE-10 octyl phenyl polyoxyethylene (3) ether HEXAETHYLENE GLYCOL MONOOCTYL ETHER emulsifier SOPE-15 complex polyalkyl phenol polyoxyethylene ether Benzethonium chloride
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View Lastest Price from 4-tert-Octylphenol manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
4-Tert-Octylphenol 140-66-9
Price
US $120.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-29
Hebei Weibang Biotechnology Co., Ltd
Product
4-tert-Octylphenol 140-66-9
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-19
Hebei Chuanghai Biotechnology Co,.LTD
Product
4-tert-Octylphenol 140-66-9
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-23

140-66-9, 4-tert-Octylphenol Related Search:

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