Description Brand Name(s) in US Reference
ChemicalBook > CAS DataBase List > SULFACHLOROPYRIDAZINE

SULFACHLOROPYRIDAZINE

Description Brand Name(s) in US Reference
Product Name
SULFACHLOROPYRIDAZINE
CAS No.
80-32-0
Chemical Name
SULFACHLOROPYRIDAZINE
Synonyms
SULFACHLORPYRIDAZINE;SULPHACHLOROPYRIDAZINE;Sulfochlorpyridazine;Sulphachlorpyridazine;Prinz;Soxilyn;Sonilyn;Cosulid;NEFROSUL;Cluricol
CBNumber
CB6724544
Molecular Formula
C10H9ClN4O2S
Formula Weight
284.72
MOL File
80-32-0.mol
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SULFACHLOROPYRIDAZINE Property

Melting point:
186-187℃
Boiling point:
559.7±60.0 °C(Predicted)
Density 
1.588
refractive index 
1.6300 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
0.5 M NaOH: soluble50mg/mL
pka
pKa 6.10 (Uncertain)
form 
powder
color 
off-white to light yellow
BRN 
261558
EPA Substance Registry System
Benzenesulfonamide, 4-amino-N-(6-chloro-3-pyridazinyl)- (80-32-0)
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Safety

Hazard Codes 
Xi
Risk Statements 
43
Safety Statements 
36/37
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
2935909550
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
46778
Product name
Sulfachloropyridazine
Purity
VETRANAL
Packaging
250mg
Price
$80.4
Updated
2024/03/01
Sigma-Aldrich
Product number
1624505
Product name
Sulfachlorpyridazine
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200mg
Price
$436
Updated
2024/03/01
Sigma-Aldrich
Product number
S9882
Product name
Sulfachloropyridazine
Packaging
100g
Price
$87.1
Updated
2022/05/15
TRC
Product number
S689061
Product name
Sulfachloropyridazine
Packaging
250mg
Price
$65
Updated
2021/12/16
Usbiological
Product number
S8016-60
Product name
Sulfachlorpyridazine
Packaging
500ul
Price
$523
Updated
2021/12/16
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SULFACHLOROPYRIDAZINE Chemical Properties,Usage,Production

Description

It is a sulfonamide antibiotic that is usually used as antibacterial anti-inflammatory drug, which has been applied in the treatment of acute urinary tract infections in childhood. Specifically, due to its antibiotic activity, this chemical has been selected as an ingredient to prepare antibacterial composition.1 Moreover, this substance can be introduced in the drinking water to fabricate aqueous liquid formulations for combating bacterial and protozoal in animals.2 In addition, this compound can act as an eco-friendly inhibitor for corrosion of mild steel in H2SO4 solution.3 Besides, sulfachloropyridazine associated to tripelennamine hydrocholoride has been demonstrated to function as an anti-stress agent in poultry after vaccinations.4

Brand Name(s) in US

Vetisulid

Reference

  1. Stolar, M. E., Synergistic antibacterial composition US Patent 4470978 1984.
  2. Gerhard Lukas; Atasoy, K., Aqueous liquid formulations for control of bacterial and protozoal diseases US Patent 4423043 1983.
  3. Omar A. Hazazi; Ahmed Fawzy; Awad, M. I., Sulfachloropyridazine as an Eco-Friendly Inhibitor for Corrosion of Mild Steel in H2SO4 Solution Chemical Science Review and Letters 2015, 4, 67-79.
  4. M. Nakano; M.N. Narimatsu; Portugal, M. A. S. C., Use of sulfachloropyridazine associated to tripelennamine hydrochloride as anti-stress agent in poultry after vaccinations. Biologico 1977.

Originator

Sonilyn,Mallinckrodt Inc.,US,1962

Uses

Sulfachloropyridazine is an antibacterial compound.This compound is a contaminant of emerging concern (CECs).

Definition

ChEBI: A sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.

Manufacturing Process

1.9 parts of 3,6-dichloropyridazine, 3.4 parts of sulfanilamide, 2.7 parts of potassium carbonate and 1 part of sodium chloride were ground together. The solid mixture was heated with stirring and as the dichloropyridazine and sulfanilamide melted, the mixture became a slurry. When the bath temperature had reached 140°C a sudden evolution of carbon dioxide occurred which lasted about 5 minutes, after which the mixture set in fine granules. When no more carbon dioxide was evolved, heating was stopped and the reaction mixture was heated with sufficient water to dissolve it and the solution allowed to cool. Unreacted sulfanilamide was collected by filtration. Excess dichloropyridazine was removed from the filtrate by extraction with a water immiscible organic solvent such as ether.
The basic solution was chilled and poured into one-half volume of 1:3 acetic acid. Sufficient hydrochloric acid was added to bring the mixture to pH 4. The crude 3-sulfanilamido-6-chloropyridazine which precipitated was purified by solution in 6 parts of 1:100 ammonium hydroxide, charcoal treatment and precipitation by pouring of the filtrate into dilute acetic acid.

brand name

Nefrosul (3M Pharmaceuticals); Sonilyn,(Carter-Wallace); Vetisulid [Veterinary] (Fort Dodge Animal Health).

Therapeutic Function

Antibacterial

SULFACHLOROPYRIDAZINE Preparation Products And Raw materials

Raw materials

Maleic anhydride Sulfanilamide Maleic hydrazide 3,6-Dichloropyridazine

Preparation Products

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View Lastest Price from SULFACHLOROPYRIDAZINE manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
SULFACHLOROPYRIDAZINE 80-32-0
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2023-02-28
Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
Sulfachloropyridazine 80-32-0
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2024-04-03
Hebei Mojin Biotechnology Co., Ltd
Product
SULFACHLOROPYRIDAZINE 80-32-0
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000tons
Release date
2023-08-15

80-32-0, SULFACHLOROPYRIDAZINERelated Search:

Sulfaquinoxaline Sulfluramid Sulfamethoxypyridazine Penicillin G sodium salt Sulfanilamide Sulfamonomethoxine SULPHADIMIDINE SODIUM 2-Methylsulfonyl-4,6-dimethoxypyrimidine 6-Chloropyridazin-3-amine 3-Aminopyridazine hydrochloride 3-CHLOROPYRIDAZINE Pyridazin-3-amine SULFACHLOROPYRIDAZINE Sulfachloropyridazine sodium Pyridazine Sulfamethazine SULFAMETHAZINE SULFADIMIDINE-D4

  • N’-(6-Chloro-3-pyridazinyl)sulfanilamide
  • Soxilyn
  • Sulphachlorpyridazine
  • VetisullideNefrosul
  • AKOS B014357
  • Nefrosul (TN)
  • Prinz
  • Sulfachlorpyridazine (USP)
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  • SULFACHLORPYRIDAZINE
  • NEFROSUL
  • TIMTEC-BB SBB001158
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  • LABOTEST-BB LT00772309
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  • 6-Sulfanilamido-3-chloropyridazine
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  • C16990100 Sulfachloropyridazine
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