6-Chloropyridazin-3-amine

Product Name: 6-Chloropyridazin-3-amine
CAS No.: 5469-69-2
Chemical Name: 6-Chloropyridazin-3-amine
Synonyms: 3-AMINO-6-CHLOROPYRIDAZINE;6-AMino-3-chloropyridazine;6-Chloropyridazin-3-amine, 3-Amino-6-chloro-1,2-diazine;3-Amino-6-chL;oropyridazine;BUTTPARK 44\01-57;TIMTEC-BB SBB005487;Risdiplam Impurity 7;Chloridazon Impurity 4;6-chloro-3-pyridazinamin
CBNumber: CB3189300
Molecular Formula: C4H4ClN3
Formula Weight: 129.55
MOL File: 5469-69-2.mol

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6-Chloropyridazin-3-amine Property

Melting point:: 210 °C
Boiling point:: 363.2±22.0 °C(Predicted)
Density: 1.437±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly, Heated)
form: Solid
pka: 4.06±0.10(Predicted)
color: Light Brown to Brown
BRN: 110918
InChI: InChI=1S/C4H4ClN3/c5-3-1-2-4(6)8-7-3/h1-2H,(H2,6,8)
InChIKey: DTXVKPOKPFWSFF-UHFFFAOYSA-N
SMILES: C1(N)=NN=C(Cl)C=C1
CAS DataBase Reference: 5469-69-2(CAS DataBase Reference)
EPA Substance Registry System: 3-Pyridazinamine, 6-chloro- (5469-69-2)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-20/21/22-22
Safety Statements: 26-36/37/39-22-36
WGK Germany: 3
Hazard Note: Irritant
TSCA: Yes
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: A1817
Product name: 3-Amino-6-chloropyridazine
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $60
Updated: 2025/07/31

TCI Chemical

Product number: A1817
Product name: 3-Amino-6-chloropyridazine
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $174
Updated: 2025/07/31

TRC

Product number: A603511
Product name: 3-Amino-6-chloropyridazine
Packaging: 5g
Price: $65
Updated: 2021/12/16

TRC

Product number: A603511
Product name: 3-Amino-6-chloropyridazine
Packaging: 100g
Price: $965
Updated: 2021/12/16

Oakwood

Product number: 018176
Product name: 3-Amino-6-chloropyridazine
Packaging: 1g
Price: $10
Updated: 2021/12/16

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6-Chloropyridazin-3-amine Chemical Properties,Usage,Production

Chemical Properties

Brown Solid

Uses

3-Amino-6-chloropyridazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Definition

ChEBI: 3(S)-hydroxy-13-cis-eicosenoyl-CoA is a member of pyridazines.

Synthesis

141-30-0

5469-69-2

The general procedure for the synthesis of 3-amino-6-chloropyridazine from 3,6-dichloropyridazine was as follows: 3,6-dichloropyridazine (107,500 mg, 3.36 mmol) was slowly added to 2.0 M ammonia methanol solution (NH3 in MeOH, 17 mL, 33.6 mmol). The reaction mixture was heated at 130 °C for 96 h and subsequently cooled to room temperature. After the reaction was completed, water was carefully added. The organic compounds were extracted with ethyl acetate and the combined organic phases were washed with saturated aqueous sodium chloride solution. The organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure. The crude product was purified by column chromatography to afford the target compound 3-amino-6-chloropyridazine (108d, 265 mg, 61% yield) as a white solid. The structure of the product was confirmed by 1H NMR (400 MHz, CD3OD) δ 6.95 (d, J = 9.6 Hz, 1H), 7.34 (d, J = 9.2 Hz, 1H) and 13C NMR (100 MHz, CD3OD) δ 119.8, 131.1, 147.1, 161.5.

References

[1] Patent: WO2013/59587, 2013, A1. Location in patent: Page/Page column 74; 75
[2] Patent: EP2768509, 2017, B1. Location in patent: Paragraph 0237; 0238
[3] Journal of Heterocyclic Chemistry, 2013, vol. 50, # 5, p. 1165 - 1173
[4] Organic and Biomolecular Chemistry, 2010, vol. 8, # 18, p. 4131 - 4136
[5] Patent: WO2007/26623, 2007, A1. Location in patent: Page/Page column 6-7

6-Chloropyridazin-3-amine Preparation Products And Raw materials

Raw materials

Ammonium hydroxide Ethanol 3,6-Dichloropyridazine

Preparation Products

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6-Chloropyridazin-3-amine Suppliers

Americas 1 Belgium 2 Canada 1 China 386 Europe 1 France 1 Germany 7 India 17 Japan 1 Switzerland 1 The Netherlands 1 United Kingdom 18 United States 40 Global 477

shanghai huiyu

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INTATRADE GmbH

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Alfa Aesar

Tel: 400-6106006
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TAIYUAN RHF CO.,LTD.

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View Lastest Price from 6-Chloropyridazin-3-amine manufacturers

Henan Fengda Chemical Co., Ltd

Product: 3-Amino-6-chloropyridazine 5469-69-2
Price: US $200.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-01-02

Dideu Industries Group Limited

Product: 6-Chloropyridazin-3-amine 5469-69-2
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-11-01

Zhuozhou Wenxi import and Export Co., Ltd

Product: 6-Chloropyridazin-3-amine 5469-69-2
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-11

5469-69-2, 6-Chloropyridazin-3-amineRelated Search:

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BUTTPARK 44\01-57

AMINO(3-)-6-CHLOROPYRIDAZINE

6-CHLOROPYRIDAZIN-3-AMINE

6-CHLORO-3-PYRIDAZINYLAMINE

6-CHLOROPYRIDAZIN-3-YLAMINE

6-Chloropyridazin-3-amine, 3-Amino-6-chloro-1,2-diazine

3-AMino-6-chloropyridazine CAS 5469-69-2

6-Chloropyridazinyl-3-amine

Pyridazine, 3-amino-6-chloro-

Pyridazine, 3-amino-6-chloro- (8CI)

6-Chloropyridazin-3-amine(96%)

3-Pyridazinamine, 6-chloro-

3-Amino-6-chL

oropyridazine

3-AMINO-6-CHLOROPYRIDAZINE

TIMTEC-BB SBB005487

6-chloro-3-pyridazinamin

3-AMINO-6-CHLOROPYRIDAZINE,6-CHLOROPYRIDAZIN-3-AMINE

6-Chloro-3-aminopyridazine

3-Amino-6-chloropyrazine

3-AMINO-6-CHLOROPYRIDAZINE 98%

6-Chloropyridazin-3-amine ,98%

6-Chloro-3-pyridazinamine

3-AMINO-6-CHLOROPYDIRAZINE

3-Amino-6-chloropyradazine

3-Amino-6-chloropyridazine ,98%

6-AMino-3-chloropyridazine

6-chloropyridazin-3-amine(SALTDATA: FREE)

3-Amino-6-chloropyridazine &gt

6-Chloropyridazin-3-amine ISO 9001：2015 REACH

3-Amino-6-chloro pyridizine

Chloridazon Impurity 4

Risdiplam Impurity 7

5469-69-2

5496-69-2

5496-69-9

amine| alkyl chloride

Chemical Amines

Pyrazines, Pyrimidines & Pyridazines

Pyridazine series

Amines

Pyrazines, Pyrimidines & Pyridazines

API intermediates

pyridazine

Building Blocks

blocks

Heterocycles

Amines and Anilines

Risdiplam