Sulfamonomethoxine
- Product Name
- Sulfamonomethoxine
- CAS No.
- 1220-83-3
- Chemical Name
- Sulfamonomethoxine
- Synonyms
- SMM;daimeton;Sulfamonomethoxine Base;ds-36;dj-1550;ici32525;ro4-3476;AKOS B014359;94tem0moxine;Sulfamethoxidine
- CBNumber
- CB8764126
- Molecular Formula
- C11H12N4O3S
- Formula Weight
- 280.3
- MOL File
- 1220-83-3.mol
Sulfamonomethoxine Property
- Melting point:
- 203-2060C
- Boiling point:
- 513℃
- Density
- 1.3936 (rough estimate)
- refractive index
- 1.6200 (estimate)
- Flash point:
- >110°(230°F)
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- solubility
- methanol: soluble10mg/mL
- pka
- pKa 5.94 (Uncertain)
- form
- powder
- color
- white to white with yellow cast
- Water Solubility
- Soluble in water at 10mg/ml with warming. Also soluble in ethanol or methanol
- BRN
- 621128
- Major Application
- clinical testing
- InChI
- InChI=1S/C11H12N4O3S/c1-18-11-6-10(13-7-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,14,15)
- InChIKey
- WMPXPUYPYQKQCX-UHFFFAOYSA-N
- SMILES
- C1(S(NC2C=C(OC)N=CN=2)(=O)=O)=CC=C(N)C=C1
- CAS DataBase Reference
- 1220-83-3(CAS DataBase Reference)
- EPA Substance Registry System
- Sulfamonomethoxine (1220-83-3)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38-43
- Safety Statements
- 26-36
- WGK Germany
- 2
- RTECS
- WP0550000
- HazardClass
- IRRITANT
- HS Code
- 29350090
- Storage Class
- 11 - Combustible Solids
- Hazard Classifications
- Eye Irrit. 2
Skin Irrit. 2
Skin Sens. 1
STOT SE 3 - Toxicity
- LD50 oral in rabbit: > 10gm/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- S0508
- Product name
- Sulfamonomethoxine
- Packaging
- 250mg
- Price
- $176
- Updated
- 2025/07/31
- Product number
- 32091
- Product name
- Sulfamonomethoxine
- Purity
- VETRANAL , analytical standard
- Packaging
- 100mg
- Price
- $109
- Updated
- 2025/07/31
- Product number
- S0592
- Product name
- Sulfamonomethoxine
- Purity
- >93.0%(HPLC)
- Packaging
- 5g
- Price
- $106
- Updated
- 2025/07/31
- Product number
- S699145
- Product name
- Sulfamonomethoxine
- Packaging
- 10g
- Price
- $820
- Updated
- 2021/12/16
- Product number
- S699145
- Product name
- Sulfamonomethoxine
- Packaging
- 50mg
- Price
- $175
- Updated
- 2021/12/16
Sulfamonomethoxine Chemical Properties,Usage,Production
Chemical Properties
White To Off-White Crystalline Powder
Uses
antibacterial
Uses
Protein binding. Inhibitor of enzyme. Sulfamonomethoxine and Trimethoprim are used for treating porcine unknown hyperpyrexia.
Definition
ChEBI: Sulfamonomethoxine is a sulfonamide and a member of benzenes.
Synthesis Reference(s)
The Journal of Organic Chemistry, 26, p. 2764, 1961 DOI: 10.1021/jo01066a034
General Description
Chemical structure: sulfonamide
Biochem/physiol Actions
Sulfamonomethoxine is a competitive inhibitor of dihydropteroate synthetase used to block the synthesis of folic acid.
Synthesis
Sodium sulfamethoxazole is commonly used in clinical practice, and the preparation method of sodium sulfamethoxazole includes the following steps:
(1) Add sulfamethoxazole and sodium hydroxide into organic solvent, and stir the reaction for 0.5-2 hours under the temperature condition of 54-98?? to get solution A;
(2) add activated carbon to solution A, stir to decolorize for 0.3-0.8 hours, filter while hot, get filtrate;
(3) The filtrate was first naturally cooled to 20-30 ??, and then at 0-5 ??, holding temperature for 1-3 hours, filtration, to get the filtrate residue;
(4) Wash the filtrate with a small amount of anhydrous ethanol, and dry in vacuum at 55~60 ?? for 2-4 hours, to get sodium sulfamethoxymethane.
Sulfamonomethoxine Preparation Products And Raw materials
Raw materials
Preparation Products
Sulfamonomethoxine Suppliers
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View Lastest Price from Sulfamonomethoxine manufacturers
- Product
- Sulfadimethoxine sodium salt 1037-50-9
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-12-11
- Product
- Sulfamonomethoxine 1220-83-3
- Price
- US $0.00/kg
- Min. Order
- 25kg
- Purity
- >99.0%
- Supply Ability
- 10tons
- Release date
- 2024-04-25
- Product
- Sulphamonomethoxine 1220-83-3
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1000kg
- Release date
- 2024-04-03