1-N-Boc-Aminocyclopentanecarboxylic acid

Product Name: 1-N-Boc-Aminocyclopentanecarboxylic acid
CAS No.: 35264-09-6
Chemical Name: 1-N-Boc-Aminocyclopentanecarboxylic acid
Synonyms: BOC-CLE-OH;Boc-AC5C-OH;Boc-Cyclolencine;BOC-CYCLOLEUCINE;BOC-NH(1)CPNE-OH;1-(Boc-amino)cycL;N-BOC-CYCLOLEUCINE;N-ALPHA-T-BUTOXYCARBONYL-CYCLOLEUCINE;Boc-1-aminocyclopentane-1-carboxy acid;BOC-1-AMINOCYCLOPENTANECARBOXYLIC ACID
CBNumber: CB6768054
Molecular Formula: C11H19NO4
Formula Weight: 229.27
MOL File: 35264-09-6.mol

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1-N-Boc-Aminocyclopentanecarboxylic acid Property

Melting point:: 130-135 °C
Boiling point:: 376.6±21.0 °C(Predicted)
Density: 1.15±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: soluble in Methanol
pka: 4.14±0.20(Predicted)
form: Crystalline Powder
color: White to off-white
Water Solubility: Soluble in hot water
BRN: 2734412
CAS DataBase Reference: 35264-09-6(CAS DataBase Reference)

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Safety

Safety Statements: 24/25
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29242990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: B3831
Product name: 1-(tert-Butoxycarbonylamino)cyclopentanecarboxylic Acid
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $47
Updated: 2023/06/20

TCI Chemical

Product number: B3831
Product name: 1-(tert-Butoxycarbonylamino)cyclopentanecarboxylic Acid
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $123
Updated: 2025/07/31

TRC

Product number: B646248
Product name: Boc-Cycloleucine
Packaging: 100mg
Price: $60
Updated: 2021/12/16

Usbiological

Product number: 236122
Product name: Boc-cycloleucine
Packaging: 1g
Price: $179
Updated: 2021/12/16

TRC

Product number: B646248
Product name: Boc-Cycloleucine
Packaging: 500mg
Price: $75
Updated: 2021/12/16

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1-N-Boc-Aminocyclopentanecarboxylic acid Chemical Properties,Usage,Production

Chemical Properties

white to off-white crystalline powder

Uses

Boc-Cycloleucine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Synthesis

24424-99-5

52-52-8

35264-09-6

Cycloleucine (1.0 g, 7.74 mmol), triethylamine (Et3N, 5.4 mL, 38.7 mmol), 1 M aqueous NaOH (7.74 mL, 7.74 mmol) and acetonitrile (CH3CN, 10 mL) were added to a 250 mL round-bottom flask. The resulting clarified solution was cooled to 0 °C, followed by the slow addition of di-tert-butyl dicarbonate ((Boc)2O). The reaction mixture was gradually warmed to room temperature and stirred continuously for 4 h. A white precipitate was generated during the reaction. After completion of the reaction, the mixture was concentrated and the residue was dissolved in a solvent mixture of ethyl acetate (EtOAc) and water (1:1, 100 mL). The organic phase was separated and the aqueous phase was acidified with 10% HCl and then extracted three times with EtOAc. All organic phases were combined, washed with water and saturated saline in turn, dried over anhydrous magnesium sulfate (MgSO4), filtered and concentrated to give 1-((tert-butoxycarbonyl)amino)cyclopentanecarboxylic acid as a white solid (1.29 g, 73% yield).

References

[1] Chemistry - A European Journal, 2011, vol. 17, # 19, p. 5256 - 5260
[2] Tetrahedron Letters, 1996, vol. 37, # 20, p. 3441 - 3444
[3] Organic Process Research and Development, 1998, vol. 2, # 4, p. 238 - 244
[4] Patent: WO2004/22534, 2004, A1. Location in patent: Page 39
[5] Patent: WO2017/21922, 2017, A1. Location in patent: Page/Page column 29

1-N-Boc-Aminocyclopentanecarboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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1-N-Boc-Aminocyclopentanecarboxylic acid Suppliers

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View Lastest Price from 1-N-Boc-Aminocyclopentanecarboxylic acid manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: Boc-Cyclolencine 35264-09-6
Price: US $1.10-9.90/KG
Min. Order: 1KG
Purity: 99%min
Supply Ability: 100KG
Release date: 2025-08-20

Career Henan Chemical Co

Product: 1-N-Boc-Aminocyclopentanecarboxylic acid 35264-09-6
Price: US $9.80/KG
Min. Order: 1KG
Purity: ≥98%
Supply Ability: 20 tons
Release date: 2020-01-10

35264-09-6, 1-N-Boc-Aminocyclopentanecarboxylic acidRelated Search:

Ethyl 2-(Chlorosulfonyl)acetate Glycine Cycloleucine EC 2.6.1.2 Folic acid Cyclopentanol Bromocyclopentane Methylcyclopentane Cyclopentane Acetaminophen Citric acid DI-TERT-BUTYL ETHER 1-N-Boc-Aminocyclopentanecarboxylic acid 1-TERT-BUTOXYCARBONYLAMINO-3-HYDROXY-CYCLOPENTANECARBOXYLIC ACID ETHYL ESTER 1-TERT-BUTOXYCARBONYLAMINO-3-HYDROXY-CYCLOPENTANECARBOXYLIC ACID 3-TERT-BUTOXY-1-TERT-BUTOXYCARBONYLAMINO-CYCLOPENTANECARBOXYLIC ACID ETHYL ESTER 3-TERT-BUTOXYCARBONYLAMINO-6-OXA-BICYCLO[3.1.0]HEXANE-3-CARBOXYLIC ACID 3-BENZYLOXY-1-TERT-BUTOXYCARBONYLAMINO-CYCLOPENTANECARBOXYLIC ACID

1-TERT-BUTYLOXYCARBONYLAMINO-CYCLOPENTANE-1-CARBOXYLIC ACID

Boc-1-aminocyclopentane-1-carboxy acid

1-N-BOC-Aminocyclopentanecarboxylic acid,98%

Boc-Cyclolencine

Boc-AC5C-OH

Boc-cycloleucine Boc-1-aMinocyclopentane-1-carboxy acid

1-N-BOC-AMinocyclopentanecarboxylic acid, 98% 1GR

1-(Boc-amino)cyclopentanecarboxylic Acid N-Boc-cycloleucine

BOC-1-AMINO-1-CYCLOPENTANECARBOXYLIC ACID

BOC-1-AMINOCYCLOPENTANE-1-CARBOXYLIC ACID

BOC-1-AMINOCYCLOPENTANECARBOXYLIC ACID

BOC-CLE-OH

BOC-CYCLOLEUCINE

BOC-NH(1)CPNE-OH

1-BOC-AMINO-CYCLOPENTANE-1-CARBOXYLIC ACID

1-(BOC-AMINO)CYCLOPENTANECARBOXYLIC ACID

1-N-BOC-AMINOCYCLOPENTANECARBOXYLIC ACID

1-TERT-BUTOXYCARBONYLAMINO-CYCLOPENTANECARBOXYLIC ACID

N-TERT-BUTOXYCARBONYL-1-AMINOCYCLOPENTANECARBOXYLIC ACID

N-ALPHA-T-BOC-1-AMINOCYCLOPENTANE CARBOXYLIC ACID

N-ALPHA-T-BUTOXYCARBONYL-CYCLOLEUCINE

N-ALPHA-T-BUTOXYCARBONYL-1-AMINO-CYCLOPENTANECARBOXYLIC ACID

N-BOC-CYCLOLEUCINE

1-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-1-cyclopentanecarboxylate

1-[(2-methylpropan-2-yl)oxycarbonylamino]cyclopentane-1-carboxylic acid

1-{[(tert-butoxy)carbonyl]amino}cyclopentane-1-carboxylic acid

1-(tert-Butoxycarbonylamino)cyclopentanecarboxylic Acid &gt

N-Boc-1-aminocyclopentane-1-carboxylic acid

1-(Boc-amino)cycL

Cyclopentanecarboxylic acid, 1-[[(1,1-dimethylethoxy)carbonyl]amino]-

1-[(2-methylpropan-2-yl)oxycarbonylamino]cyclopentane-1-carboxylicaci

1-N-Boc-Aminocyclopentanecarboxylic acid USP/EP/BP

35264-09-6

CH33CO2CNHC5H8CO2H

Alicyclic Amino Acids

Specialty Synthesis

Peptide Synthesis

Unnatural Amino Acid Derivatives

pharmacetical