ChemicalBook > CAS DataBase List > 2,3-Dichlorophenylboronic acid

2,3-Dichlorophenylboronic acid

Product Name
2,3-Dichlorophenylboronic acid
CAS No.
151169-74-3
Chemical Name
2,3-Dichlorophenylboronic acid
Synonyms
AKOS BRN-0159;CAS:151169-74-3;RARECHEM AH PB 0262;3,4-Dichlorophenylboric acid;2,3-Dichlorophenylboronicaci;2,3-Dichloropheyl Boronic Acid;2,3-Dichlorophenylbrornic acid;2,3-DICHLOROPHENYLBORONIC ACID;2,3-DICHLOROBENZENEBORONIC ACID;B-(2,3-Dichlorophenyl)boronic acid
CBNumber
CB6768276
Molecular Formula
C6H5BCl2O2
Formula Weight
190.82
MOL File
151169-74-3.mol
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2,3-Dichlorophenylboronic acid Property

Melting point:
125 °C (dec.) (lit.)
Boiling point:
349.8±52.0 °C(Predicted)
Density 
1.47±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
Soluble in methanol.
pka
7.26±0.58(Predicted)
form 
Powder
color 
White
InChI
InChI=1S/C6H5BCl2O2/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3,10-11H
InChIKey
TYIKXPOMOYDGCS-UHFFFAOYSA-N
SMILES
B(C1=CC=CC(Cl)=C1Cl)(O)O
CAS DataBase Reference
151169-74-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
36/37/38-22
Safety Statements 
37/39-26-36
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29319090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
514047
Product name
2,3-Dichlorophenylboronic acid
Packaging
5g
Price
$57
Updated
2023/06/20
Sigma-Aldrich
Product number
514047
Product name
2,3-Dichlorophenylboronic acid
Packaging
25g
Price
$219
Updated
2023/06/20
TCI Chemical
Product number
D3434
Product name
2,3-Dichlorophenylboronic Acid (contains varying amounts of Anhydride)
Packaging
5g
Price
$63
Updated
2025/07/31
TCI Chemical
Product number
D3434
Product name
2,3-Dichlorophenylboronic Acid (contains varying amounts of Anhydride)
Packaging
25g
Price
$206
Updated
2025/07/31
TRC
Product number
D436600
Product name
2,3-Dichlorophenylboronic acid
Packaging
25g
Price
$250
Updated
2021/12/16
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2,3-Dichlorophenylboronic acid Chemical Properties,Usage,Production

Chemical Properties

white powder

Uses

suzuki reaction

Uses

2,3-Dichlorophenylboronic Acid is used as a reagent in the synthesis of trisubstituted thiazoles as Cdc7 kinase inhibitors. It is also used as a reagent in the synthesis of aminoarylpyridazines as selective CB2 agonists for treatment of inflammatory pain.

Synthesis

121-43-7

56961-77-4

151169-74-3

1. A solution was prepared by dissolving 1-bromo-2,3-dichlorobenzene (20 g, 0.088 mol, Aldrich) in anhydrous tetrahydrofuran (44.24 ml) under the protection of dry inert gas. 2. The above solution was slowly added dropwise to anhydrous tetrahydrofuran (16 ml) of n-butyllithium (1.6 M in hexane, 66.36 ml, 0.11 mol) solution, with the reaction temperature strictly controlled below -65°C. 3. After the dropwise addition, the light yellow suspension formed was stirred continuously at -78°C for 75 min. 4. Trimethyl borate (13.28 ml, 12.16 g, 0.12 mol) was slowly added while keeping the temperature below -55°C. 5. The reaction mixture was gradually warmed up to room temperature and stirred overnight. 6. Excess n-butyllithium was quenched with water (30 ml) and the reaction mixture was subsequently concentrated under reduced pressure.7. The concentrated residue was suspended in water and acidified with 2M hydrochloric acid (10 ml).8. The insoluble solid was collected by filtration, washed well with water and then dried.9. The dried solid was suspended in petroleum ether at 60-80°C, stirred at room temperature for 10 min, filtered and dried under vacuum.10. Finally, 8.42 g of 2,3-dichlorophenylboronic acid was obtained in 50% yield with a melting point of 235-238 °C.

References

[1] Patent: US6255307, 2001, B1

2,3-Dichlorophenylboronic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2,3-Dichlorophenylboronic acid manufacturers

Hebei Maison Chemical Co.,Ltd.
Product
2,3-Dichlorophenylboronic acid 151169-74-3
Price
US $0.00/kg
Min. Order
1kg
Purity
≥99.0%
Supply Ability
1000kg
Release date
2023-04-23
Career Henan Chemical Co
Product
2,3-Dichlorophenylboronic acid 151169-74-3
Price
US $1.00/KG
Min. Order
1KG
Purity
98%-100%
Supply Ability
1
Release date
2018-08-12

151169-74-3, 2,3-Dichlorophenylboronic acidRelated Search:

1,3-Dichlorobenzene 1,2-Dichlorobenzene 4-Chlorophenylboronic acid Lobenzarit disodium Phenylboronic acid Folic acid Ethyl 2-(Chlorosulfonyl)acetate 2,4-Dichlorobenzyl chloride Permethrin Citric acid Ascoric Acid p-Dichlorobenzene 3-Chlorophenylboronic acid 2,3,5-TRICHLOROBENZENEBORONIC ACID 2,3,4-Trichlorophenylboronic acid 2,4-DICHLOROPHENYLBORONIC ACID, PINACOL ESTER 2,6-DICHLOROPHENYLBORONIC ACID 3,5-Dichlorophenylboronic acid

  • BORONICACID, B-(2,3-DICHLOROPHENYL)-
  • 2,3-Dichlorophenylbrornic acid
  • (2,3-Dichlorophenyl)dihydroxyborane
  • 2,3-DICHLOROBENZENEBORONIC ACID
  • 2,3-DICHLOROPHENYLBORONIC ACID
  • B-(2,3-Dichlorophenyl)boronic acid
  • AKOS BRN-0159
  • RARECHEM AH PB 0262
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  • 2,3-Dichlorobenzeneboronic acid, 98+%
  • 2,3-Dichlorophenylboronic Acid (contains varying amounts of Anhydride)
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  • 2,3-Dichlorophenylboronic acid ,98%
  • 2,3-Dichlorophenylboronic acid, 97% 1GR
  • 2,3-Dichlorophenylboronicaci
  • CAS:151169-74-3
  • 2,3-Dichlorophenylboronic acid - [D2480]
  • 151169-74-3
  • 151169-74-2
  • 15169-74-3
  • 151169-7-3
  • 151196-74-3
  • 151196-74-3
  • Cl2C6H3BOH2
  • BORONIC ACID
  • Organometallic Reagents
  • Aryl
  • Boronic Acids
  • Boronic Acids and Derivatives
  • Boronate Ester
  • Potassium Trifluoroborate
  • B (Classes of Boron Compounds)
  • Boronic Acids
  • Substituted Boronic Acids
  • Boronic Acid
  • Aryl
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  • blocks
  • BoronicAcids