ChemicalBook > CAS DataBase List > 4-CHLOROPICOLINALDEHYDE

4-CHLOROPICOLINALDEHYDE

Product Name: 4-CHLOROPICOLINALDEHYDE
CAS No.: 63071-13-6
Chemical Name: 4-CHLOROPICOLINALDEHYDE
Synonyms: oropyridine-2-carbaL;4-Chloropicolaldehyde;4-CHLOROPICOLINALDEHYDE;Picolinaldehyde, 4-chloro-;4-Chloro-2-aldehyde pyridine;4-chloropyridine-2-carbaldehyde;4-chloro-2-pyridinecarbaldehyde;4-CHLOROPYRIDINE-2-CARBOXALDEHYDE;4-Chloro-2-pyridinecarboxaldehyde;2-Pyridinecarboxaldehyde,4-chloro-
CBNumber: CB6782472
Molecular Formula: C6H4ClNO
Formula Weight: 141.56
MOL File: 63071-13-6.mol

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4-CHLOROPICOLINALDEHYDE Property

Melting point:: 32-34°
Boiling point:: 206℃
Density: 1.332
Flash point:: 79℃
storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 1.78±0.10(Predicted)
color: Off-White to Pale Yellow
Stability:: Air Sensitive

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Safety

Risk Statements: 43
Safety Statements: 36/37
HazardClass: IRRITANT
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: C380345
Product name: 4-Chloro-2-pyridinecarboxaldehyde
Packaging: 5g
Price: $275
Updated: 2021/12/16

Matrix Scientific

Product number: 048191
Product name: 4-Chloro-2-pyridinecarbaldehyde
Purity: 97%
Packaging: 1g
Price: $75
Updated: 2021/12/16

Apolloscientific

Product number: OR303780
Product name: 4-Chloro-2-pyridinecarbaldehyde
Purity: 97%
Packaging: 5g
Price: $102
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC32275
Product name: 4-Chloro-2-pyridinecarbaldehyde
Packaging: 5G
Price: $115
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H56-5-0A
Product name: 4-Chloro-2-pyridinecarbaldehyde
Packaging: 1g
Price: $118
Updated: 2021/12/16

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4-CHLOROPICOLINALDEHYDE Chemical Properties,Usage,Production

Uses

4-Chloro-2-pyridinecarboxaldehyde is a useful synthetic intermediate. It is used in the synthesis of 2,2''-bipyridines, (chloropyridyl)(pyridyl)ethylamine and aryl and heteroaryl fluoromethyl ketones.

Synthesis

24484-93-3

63071-13-6

General procedure for the synthesis of 4-chloro-2-pyridinecarboxaldehyde from methyl 4-chloropyridinecarboxylate: to a solution of methyl 4-chloropyridinecarboxylate (2.5 g, 14.6 mmol) in anhydrous THF (100 mL) was added slowly and dropwise diisobutylaluminum hydride (1.0 M solution in THF, 29.1 mmol) at -78 °C and the reaction was stirred in an argon atmosphere at that temperature mixture for 2 hours. Upon completion of the reaction, the reaction was quenched with methanol (MeOH) at -78 °C, followed by the addition of potassium sodium tartrate solution (1.0 M, 180 mL), and the mixture was stirred and gradually warmed to room temperature over a period of 1 hour. The reaction mixture was diluted with ethyl acetate (EtOAc, 60 mL) and the organic layer was separated, washed with saturated saline and dried with anhydrous sodium sulfate. The solvent was removed by mild decompression distillation at room temperature to afford the target product 4-chloro-2-pyridinecarboxaldehyde (1.87 g, 91% yield), which solidified to light yellow crystals after standing at room temperature.

References

[1] Patent: US2004/186114, 2004, A1. Location in patent: Page/Page column 69; 70
[2] Patent: EP1897880, 2008, A1. Location in patent: Page/Page column 16
[3] Inorganic Chemistry, 2013, vol. 52, # 11, p. 6481 - 6501
[4] Bulletin of the Chemical Society of Japan, 2015, vol. 88, # 6, p. 784 - 791

4-CHLOROPICOLINALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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China 138 Germany 2 India 3 United Kingdom 3 United States 14 Global 160

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View Lastest Price from 4-CHLOROPICOLINALDEHYDE manufacturers

LY Global chemicals co.,ltd .

Product: 4-CHLOROPICOLINALDEHYDE 63071-13-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98% Min
Supply Ability: 1000kg
Release date: 2023-03-18

Dideu Industries Group Limited

Product: 4-CHLOROPICOLINALDEHYDE 63071-13-6
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-10-28

Career Henan Chemical Co

Product: 4-CHLOROPICOLINALDEHYDE 63071-13-6
Price: US $1.00/ASSAYS
Min. Order: 1ASSAYS
Purity: 85.0-99.8%
Supply Ability: 20tons
Release date: 2020-01-08

63071-13-6, 4-CHLOROPICOLINALDEHYDERelated Search:

4-CHLOROPYRIDINE-2,6-DICARBOHYDRAZIDE N-Methyl-4-chloropyridine-2-carboxamide dimethyl 4-chloropyridine-2,6-dicarboxylate 2-Chloro-3-pyridinecarboxaldehyde 4-CHLORO-PYRIDINE-2-CARBOXYLIC ACID HYDRAZIDE Tetrachloropyridine-2-carboxylic acid 3,4,5-Trichloropyridine-2-carboxylic acid 4-Chloropyridine-2-carboxamide 4-Chloropyridine-2-carboxylic acid 6-Chloropicolinaldehyde 2 6-DICHLOROPYRIDINE-3-CARBOXALDEHYDE 2-Chloroisonicotinaldehyde 2-Chloropyridine-5-carbaldehyde 2,3,5-Trichloropyridine-4-carboxaldehyde METHYL 3,4,5,6-TETRACHLOROPYRIDINE-2-CARBOXYLATE 3,4-DICHLOROPICOLINIC ACID 3,4,5-Trichloro-6-hydroxypyridine-2-carboxylic acid DIETHYL 4-CHLORO-2,6-PYRIDINEDICARBOXYLATE

4-Chloro-2-pyridinecarboxaldehyde

4-CHLOROPICOLINALDEHYDE

4-CHLOROPYRIDINE-2-CARBOXALDEHYDE

4-chloro-2-pyridinecarbaldehyde

4-Chloropyridin-2-ylcarboxaldehyde

2-Pyridinecarboxaldehyde,4-chloro-

Picolinaldehyde, 4-chloro-

4-chloropyridine-2-carbaldehyde

oropyridine-2-carbaL

4-CHLOROPICOLINALDEHYDE ISO 9001：2015 REACH

4-Chloropyridine-2-carbaldehyde4-Chloropyridine-2-carbaldehyde

4-Chloro-2-aldehyde pyridine

4-Chloropicolaldehyde

63071-13-6

Pyridines