ChemicalBook > CAS DataBase List > 6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER

6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER

Product Name
6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER
CAS No.
215312-86-0
Chemical Name
6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER
Synonyms
SULFO-EMCS;SULPHO EMCS;6-Maleimidocaproic acid sulfo-NHS;N-(E-MALEIMIDOCAPROYLOXY)SULPHOSUCCINIMIDE;N-(E-MALEIMIDOCAPROYLOXY)-SULFOSUCCINIMIDE;6-Maleimidocaproic acid sulfo-NHS (sodium);N-([ε-Maleimidocaproyloxy)sulfosuccinimide ester;6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER;Sulfo-N-Succinimidyl 6-Maleimidocaproate Sodium Salt;N-[EPSILON-MALEIMIDOCAPROYLOXY]SULFOSUCCINIMIDE ESTER
CBNumber
CB6793735
Molecular Formula
C14H16N2O9S
Formula Weight
0
MOL File
Mol file
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6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER Property

Melting point:
158-165°C
storage temp. 
2-8°C
solubility 
DMSO (Slightly, Sonicated)
form 
Solid
color 
White to Pale Yellow
Stability:
Moisture Sensitive
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Safety

HS Code 
2928.00.5000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
803235
Product name
Sulfo-EMCS (N-(ε-maleimidocaproyloxy) sulfosuccinimide ester)
Packaging
50mg
Price
$453
Updated
2023/06/20
TCI Chemical
Product number
U0122
Product name
Sulfo-EMCS
Packaging
25MG
Price
$172
Updated
2024/03/01
TCI Chemical
Product number
U0122
Product name
Sulfo-EMCS
Packaging
100MG
Price
$515
Updated
2024/03/01
TRC
Product number
M137000
Product name
6-MaleimidocaproicAcidSulfo-N-SuccinimidylEster
Packaging
50mg
Price
$135
Updated
2021/12/16
Usbiological
Product number
284148
Product name
6-Maleimidocaproic acid sulfo-NHS
Packaging
25mg
Price
$366
Updated
2021/12/16
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6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

A water soluble sulfhydryl and amio reactive heterobifunctional crosslinking reagent. Spacer Arm: 9.4 Angstroms

Uses

A water soluble sulfhydryl and amio reactive heterobifunctional crosslinking reagent.Spacer Arm: 9.4 Angstroms

General Description

EMCS and its water-soluble analog Sulfo-EMCS are heterobifunctional cross-linkers that contain N-hydroxysuccinimide (NHS) ester and maleimide groups that allow covalent conjugation of amine- and sulfhydryl-containing molecules. NHS esters react with primary amines at pH 7-9 to form amide bonds, while maleimides react with sulfhydryl groups at pH 6.5-7.5 to form stable thioether bonds. In aqueous solutions, hydrolytic degradation of the NHS ester is a competing reaction whose rate increases with pH. The maleimide group is more stable than the NHS-ester group but will slowly hydrolyze and also lose its reaction specificity for sulfhydryls at pH values > 7.5. For these reasons, conjugation experiments involving these cross-linkers are usually performed at pH 7.2-7.5, with the NHS-ester (amine-targeted) reaction being accomplished before or simultaneous with the maleimide (sulfhydryl-targeted) reaction.

6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER Suppliers

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View Lastest Price from 6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER 215312-86-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER 215312-86-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08
Career Henan Chemical Co
Product
215312-86-0 215312-86-0
Price
US $1.00/KG
Min. Order
1KG
Purity
≥98%
Supply Ability
200KG
Release date
2019-08-30

215312-86-0, 6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTERRelated Search:

M-MALEIMIDOBENZOYL-N-HYDROXYSULFOSUCCINIMIDE ESTER SUCCINIMIDYL 4-FORMYLBENZOATE Biotin-PEG6-Mal SATP 4-(4-N-maleimidophenyl)butyric acid hydrazide (R)-(+)-N-(1-PHENYLETHYL)MALEIMIDE DISUCCINIMIDYL SUBERATE N-Succinimidyl 11-(maleimido)undecanoate N-Succinimidyl 6-maleimidohexanoate N-Succinimidyl 3-maleimidopropionate 4-MALEIMIDOBUTYRIC ACID 2-Maleimido acetic acid GMBS 11-Maleimidoundecanoic acid 3-Maleimidopropionic acid N-Succinimidyl maleimidoacetate 3-Maleimidobenzoic acid N-hydroxysuccinimide ester 6-Maleimidocaproic acid

  • 6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER
  • N-(E-MALEIMIDOCAPROYLOXY)-SULFOSUCCINIMIDE
  • N-(E-MALEIMIDOCAPROYLOXY)SULPHOSUCCINIMIDE
  • N-[EPSILON-MALEIMIDOCAPROYLOXY]SULFOSUCCINIMIDE ESTER
  • SULPHO EMCS
  • SULFO-EMCS
  • 6-Maleimidocaproic acid sulfo-NHS
  • 1-[[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]oxy]-2,5-dioxo-3-pyrrolidinesulfonic Acid SodiuM Salt
  • N-(ε-MaleiMidocaproyloxy)sulfosucciniMide ester(Sulfo-EMCS)
  • N-([ε-Maleimidocaproyloxy)sulfosuccinimide ester
  • Sulfo-EMCS N-([ε-Maleimidocaproyloxy)sulfosuccinimide ester
  • Sodium 1-((6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl)oxy)-2,5-dioxopyrrolidine-3-sulfonate
  • 6-Maleimidocaproic Acid Sulfo-N-Succinimidyl Ester Sodium Salt
  • Sulfo-N-Succinimidyl 6-Maleimidocaproate Sodium Salt
  • 6-Maleimidocaproic acid sulfo-NHS (sodium)
  • 215312-86-0
  • C14H16N2O9S
  • C14H15N2O9SNa
  • C14H15N2NaO9S
  • Proteomics and Protein Expression
  • Protein Modification
  • Proteomics
  • Organic Building Blocks
  • Cyclic Imides
  • Crosslinking
  • Heterobifunctional Cross-Linking Reagents
  • BioChemical
  • Building Blocks
  • Carbonyl Compounds
  • Cross Linking Reagents
  • MTS & Sulfhydryl Active Reagents
  • Maleimide Derivatives
  • heteroXlink
  • 1