6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER
- Product Name
- 6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER
- CAS No.
- 215312-86-0
- Chemical Name
- 6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER
- Synonyms
- SULFO-EMCS;SULPHO EMCS;6-Maleimidocaproic acid sulfo-NHS;N-(E-MALEIMIDOCAPROYLOXY)SULPHOSUCCINIMIDE;N-(E-MALEIMIDOCAPROYLOXY)-SULFOSUCCINIMIDE;6-Maleimidocaproic acid sulfo-NHS (sodium);N-([ε-Maleimidocaproyloxy)sulfosuccinimide ester;6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER;Sulfo-N-Succinimidyl 6-Maleimidocaproate Sodium Salt;N-[EPSILON-MALEIMIDOCAPROYLOXY]SULFOSUCCINIMIDE ESTER
- CBNumber
- CB6793735
- Molecular Formula
- C14H16N2O9S
- Formula Weight
- 0
- MOL File
- Mol file
6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER Property
- Melting point:
- 158-165°C
- storage temp.
- 2-8°C
- solubility
- DMSO (Slightly, Sonicated)
- form
- Solid
- color
- White to Pale Yellow
- Water Solubility
- water: soluble
- Stability:
- Moisture Sensitive
Safety
- HS Code
- 2928.00.5000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- 803235
- Product name
- Sulfo-EMCS (N-(ε-maleimidocaproyloxy) sulfosuccinimide ester)
- Packaging
- 50mg
- Price
- $453
- Updated
- 2023/06/20
- Product number
- U0122
- Product name
- Sulfo-EMCS
- Packaging
- 25MG
- Price
- $172
- Updated
- 2024/03/01
- Product number
- U0122
- Product name
- Sulfo-EMCS
- Packaging
- 100MG
- Price
- $515
- Updated
- 2024/03/01
- Product number
- M137000
- Product name
- 6-MaleimidocaproicAcidSulfo-N-SuccinimidylEster
- Packaging
- 50mg
- Price
- $135
- Updated
- 2021/12/16
- Product number
- 284148
- Product name
- 6-Maleimidocaproic acid sulfo-NHS
- Packaging
- 25mg
- Price
- $366
- Updated
- 2021/12/16
6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
A water soluble sulfhydryl and amio reactive heterobifunctional crosslinking reagent. Spacer Arm: 9.4 Angstroms
Uses
A water soluble sulfhydryl and amio reactive heterobifunctional crosslinking reagent.Spacer Arm: 9.4 Angstroms
General Description
EMCS and its water-soluble analog Sulfo-EMCS are heterobifunctional cross-linkers that contain N-hydroxysuccinimide (NHS) ester and maleimide groups that allow covalent conjugation of amine- and sulfhydryl-containing molecules. NHS esters react with primary amines at pH 7-9 to form amide bonds, while maleimides react with sulfhydryl groups at pH 6.5-7.5 to form stable thioether bonds. In aqueous solutions, hydrolytic degradation of the NHS ester is a competing reaction whose rate increases with pH. The maleimide group is more stable than the NHS-ester group but will slowly hydrolyze and also lose its reaction specificity for sulfhydryls at pH values > 7.5. For these reasons, conjugation experiments involving these cross-linkers are usually performed at pH 7.2-7.5, with the NHS-ester (amine-targeted) reaction being accomplished before or simultaneous with the maleimide (sulfhydryl-targeted) reaction.
reaction suitability
reagent type: cross-linking reagent
6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER manufacturers
- Product
- 6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER 215312-86-0
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER 215312-86-0
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-08
- Product
- 215312-86-0 215312-86-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- ≥98%
- Supply Ability
- 200KG
- Release date
- 2019-08-30