ChemicalBook > CAS DataBase List > 6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER

6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER

Product Name: 6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER
CAS No.: 215312-86-0
Chemical Name: 6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER
Synonyms: SULFO-EMCS;SULPHO EMCS;6-Maleimidocaproic acid sulfo-NHS;N-(E-MALEIMIDOCAPROYLOXY)SULPHOSUCCINIMIDE;N-(E-MALEIMIDOCAPROYLOXY)-SULFOSUCCINIMIDE;6-Maleimidocaproic acid sulfo-NHS (sodium);N-([ε-Maleimidocaproyloxy)sulfosuccinimide ester;6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER;Sulfo-N-Succinimidyl 6-Maleimidocaproate Sodium Salt;N-[EPSILON-MALEIMIDOCAPROYLOXY]SULFOSUCCINIMIDE ESTER
CBNumber: CB6793735
Molecular Formula: C14H16N2O9S
Formula Weight: 0
MOL File: Mol file

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6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER Property

Melting point:: 158-165°C
storage temp.: 2-8°C
solubility: DMSO (Slightly, Sonicated)
form: Solid
color: White to Pale Yellow
Water Solubility: water: soluble
Stability:: Moisture Sensitive

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Safety

HS Code: 2928.00.5000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 803235
Product name: Sulfo-EMCS (N-(ε-maleimidocaproyloxy) sulfosuccinimide ester)
Packaging: 50mg
Price: $453
Updated: 2023/06/20

TCI Chemical

Product number: U0122
Product name: Sulfo-EMCS
Packaging: 25MG
Price: $163
Updated: 2025/07/31

TCI Chemical

Product number: U0122
Product name: Sulfo-EMCS
Packaging: 100MG
Price: $489
Updated: 2025/07/31

TRC

Product number: M137000
Product name: 6-MaleimidocaproicAcidSulfo-N-SuccinimidylEster
Packaging: 50mg
Price: $135
Updated: 2021/12/16

Usbiological

Product number: 284148
Product name: 6-Maleimidocaproic acid sulfo-NHS
Packaging: 25mg
Price: $366
Updated: 2021/12/16

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6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

A water soluble sulfhydryl and amio reactive heterobifunctional crosslinking reagent. Spacer Arm: 9.4 Angstroms

Uses

A water soluble sulfhydryl and amio reactive heterobifunctional crosslinking reagent.Spacer Arm: 9.4 Angstroms

General Description

EMCS and its water-soluble analog Sulfo-EMCS are heterobifunctional cross-linkers that contain N-hydroxysuccinimide (NHS) ester and maleimide groups that allow covalent conjugation of amine- and sulfhydryl-containing molecules. NHS esters react with primary amines at pH 7-9 to form amide bonds, while maleimides react with sulfhydryl groups at pH 6.5-7.5 to form stable thioether bonds. In aqueous solutions, hydrolytic degradation of the NHS ester is a competing reaction whose rate increases with pH. The maleimide group is more stable than the NHS-ester group but will slowly hydrolyze and also lose its reaction specificity for sulfhydryls at pH values > 7.5. For these reasons, conjugation experiments involving these cross-linkers are usually performed at pH 7.2-7.5, with the NHS-ester (amine-targeted) reaction being accomplished before or simultaneous with the maleimide (sulfhydryl-targeted) reaction.

reaction suitability

reagent type: cross-linking reagent

6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER Suppliers

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View Lastest Price from 6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER 215312-86-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER 215312-86-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

Career Henan Chemical Co

Product: 215312-86-0 215312-86-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: ≥98%
Supply Ability: 200KG
Release date: 2019-08-30

215312-86-0, 6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTERRelated Search:

M-MALEIMIDOBENZOYL-N-HYDROXYSULFOSUCCINIMIDE ESTER SUCCINIMIDYL 4-FORMYLBENZOATE Biotin-PEG6-Mal SATP 4-(4-N-maleimidophenyl)butyric acid hydrazide (R)-(+)-N-(1-PHENYLETHYL)MALEIMIDE DISUCCINIMIDYL SUBERATE N-Succinimidyl 11-(maleimido)undecanoate N-Succinimidyl 6-maleimidohexanoate N-Succinimidyl 3-maleimidopropionate 4-MALEIMIDOBUTYRIC ACID 2-Maleimido acetic acid GMBS 11-Maleimidoundecanoic acid 3-Maleimidopropionic acid N-Succinimidyl maleimidoacetate 3-Maleimidobenzoic acid N-hydroxysuccinimide ester 6-Maleimidocaproic acid

6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER

N-(E-MALEIMIDOCAPROYLOXY)-SULFOSUCCINIMIDE

N-(E-MALEIMIDOCAPROYLOXY)SULPHOSUCCINIMIDE

N-[EPSILON-MALEIMIDOCAPROYLOXY]SULFOSUCCINIMIDE ESTER

SULPHO EMCS

SULFO-EMCS

6-Maleimidocaproic acid sulfo-NHS

1-[[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]oxy]-2,5-dioxo-3-pyrrolidinesulfonic Acid SodiuM Salt

N-(ε-MaleiMidocaproyloxy)sulfosucciniMide ester(Sulfo-EMCS)

N-([ε-Maleimidocaproyloxy)sulfosuccinimide ester

Sulfo-EMCS N-([ε-Maleimidocaproyloxy)sulfosuccinimide ester

Sodium 1-((6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl)oxy)-2,5-dioxopyrrolidine-3-sulfonate

6-Maleimidocaproic Acid Sulfo-N-Succinimidyl Ester Sodium Salt

Sulfo-N-Succinimidyl 6-Maleimidocaproate Sodium Salt

6-Maleimidocaproic acid sulfo-NHS (sodium)

215312-86-0

C14H16N2O9S

C14H15N2O9SNa

C14H15N2NaO9S

Proteomics and Protein Expression

Protein Modification

Proteomics

Organic Building Blocks

Cyclic Imides

Crosslinking

Heterobifunctional Cross-Linking Reagents

BioChemical

Building Blocks

Carbonyl Compounds

Cross Linking Reagents

MTS & Sulfhydryl Active Reagents

Maleimide Derivatives

heteroXlink