N-Succinimidyl 6-maleimidohexanoate
- Product Name
- N-Succinimidyl 6-maleimidohexanoate
- CAS No.
- 55750-63-5
- Chemical Name
- N-Succinimidyl 6-maleimidohexanoate
- Synonyms
- 2,5-dioxopyrrolidin-1-yl 6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoate;EMCS;MCOSU;6-maleimidohexanoic acid N-hydroxylsuccinimide ester;6-MALEIMIDOCAPROIC ACID N-SUCCINIMIDYL ESTER;6-Maleimidohexanoic acid N-hydroxysuccinimide ester;(2,5-Dioxopyrrolidin-1-yl) 6-(2,5-dioxopyrrol-1-yl)hexanoate;EMCS Crosslinker;maleimide-(CH2)5-NHS;NHS-(CH2)5-Mal (EMCS)
- CBNumber
- CB8212960
- Molecular Formula
- C14H16N2O6
- Formula Weight
- 308.29
- MOL File
- 55750-63-5.mol
N-Succinimidyl 6-maleimidohexanoate Property
- Melting point:
- 70-73 °C(lit.)
- Boiling point:
- 480.6±47.0 °C(Predicted)
- Density
- 1.40±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- chloroform: 100mg/mL
- form
- powder
- pka
- -2.21±0.20(Predicted)
- color
- Off-white to pale brown
- Sensitive
- Light & Moisture Sensitive & Hygroscopic
- BRN
- 1499815
- InChI
- InChI=1S/C14H16N2O6/c17-10-5-6-11(18)15(10)9-3-1-2-4-14(21)22-16-12(19)7-8-13(16)20/h5-6H,1-4,7-9H2
- InChIKey
- VLARLSIGSPVYHX-UHFFFAOYSA-N
- SMILES
- N1(CCCCCC(ON2C(=O)CCC2=O)=O)C(=O)C=CC1=O
- CAS DataBase Reference
- 55750-63-5(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 36/37/38-40
- Safety Statements
- 26-36/37-36
- WGK Germany
- 3
- F
- 8-10-21
- HS Code
- 29280000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 63177
- Product name
- 6-Maleimidohexanoic acid N-hydroxysuccinimide ester
- Purity
- ≥98.0% (HPLC)
- Packaging
- 25mg
- Price
- $215
- Updated
- 2024/03/01
- Product number
- 568600
- Product name
- 6-Maleimidohexanoic acid N-hydroxysuccinimide ester
- Purity
- 98%
- Packaging
- 500mg
- Price
- $244
- Updated
- 2024/03/01
- Product number
- S0428
- Product name
- N-Succinimidyl 6-Maleimidohexanoate [Cross-linking Reagent]
- Purity
- >98.0%(N)
- Packaging
- 1g
- Price
- $98
- Updated
- 2024/03/01
- Product number
- H65996
- Product name
- 6-Maleimidocaproic acid N-succinimidyl ester, 95%
- Packaging
- 250mg
- Price
- $118.65
- Updated
- 2024/03/01
- Product number
- H65996
- Product name
- 6-Maleimidocaproic acid N-succinimidyl ester, 95%
- Packaging
- 1g
- Price
- $372.65
- Updated
- 2024/03/01
N-Succinimidyl 6-maleimidohexanoate Chemical Properties,Usage,Production
Description
Mal-heptanoic NHS ester contains a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
Chemical Properties
White to cream colored crystals
Uses
6-Maleimidohexanoic acid N-hydroxysuccinimide ester can be used in:
- Synthesis of maleimide-activated carbohydrates for site-specific glycosylation of cysteine-containing peptides and proteins via maleimide-thiol ligation reaction.
- Synthesis of a glucuronide prodrug of doxorubicin bearing a maleimide side chain as an antitumor agent.
- Cross-linking oligonucleotides with the amino groups on the substrate to fabricate DNA microarrays.
N-Succinimidyl 6-maleimidohexanoate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from N-Succinimidyl 6-maleimidohexanoate manufacturers
- Product
- N-Succinimidyl 6-maleimidohexanoate 55750-63-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-13
- Product
- N-Succinimidyl 6-maleimidohexanoate 55750-63-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- N-Succinimidyl 6-maleimidohexanoate 55750-63-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-08