ChemicalBook > CAS DataBase List > 6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER

6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER

Product Name
6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER
CAS No.
215312-86-0
Chemical Name
6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER
Synonyms
SULFO-EMCS;SULPHO EMCS;6-Maleimidocaproic acid sulfo-NHS;N-(E-MALEIMIDOCAPROYLOXY)SULPHOSUCCINIMIDE;N-(E-MALEIMIDOCAPROYLOXY)-SULFOSUCCINIMIDE;6-Maleimidocaproic acid sulfo-NHS (sodium);N-([ε-Maleimidocaproyloxy)sulfosuccinimide ester;6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER;Sulfo-N-Succinimidyl 6-Maleimidocaproate Sodium Salt;N-[EPSILON-MALEIMIDOCAPROYLOXY]SULFOSUCCINIMIDE ESTER
CBNumber
CB6793735
Molecular Formula
C14H16N2O9S
Formula Weight
0
MOL File
Mol file
More
Less

6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER Property

Melting point:
158-165°C
storage temp. 
2-8°C
solubility 
DMSO (Slightly, Sonicated)
form 
Solid
color 
White to Pale Yellow
Stability:
Moisture Sensitive
More
Less

Safety

HS Code 
2928.00.5000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
803235
Product name
Sulfo-EMCS (N-(ε-maleimidocaproyloxy) sulfosuccinimide ester)
Packaging
50mg
Price
$453
Updated
2023/06/20
TCI Chemical
Product number
U0122
Product name
Sulfo-EMCS
Packaging
25MG
Price
$172
Updated
2024/03/01
TCI Chemical
Product number
U0122
Product name
Sulfo-EMCS
Packaging
100MG
Price
$515
Updated
2024/03/01
TRC
Product number
M137000
Product name
6-MaleimidocaproicAcidSulfo-N-SuccinimidylEster
Packaging
50mg
Price
$135
Updated
2021/12/16
Usbiological
Product number
284148
Product name
6-Maleimidocaproic acid sulfo-NHS
Packaging
25mg
Price
$366
Updated
2021/12/16
More
Less

6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

A water soluble sulfhydryl and amio reactive heterobifunctional crosslinking reagent. Spacer Arm: 9.4 Angstroms

Uses

A water soluble sulfhydryl and amio reactive heterobifunctional crosslinking reagent.Spacer Arm: 9.4 Angstroms

General Description

EMCS and its water-soluble analog Sulfo-EMCS are heterobifunctional cross-linkers that contain N-hydroxysuccinimide (NHS) ester and maleimide groups that allow covalent conjugation of amine- and sulfhydryl-containing molecules. NHS esters react with primary amines at pH 7-9 to form amide bonds, while maleimides react with sulfhydryl groups at pH 6.5-7.5 to form stable thioether bonds. In aqueous solutions, hydrolytic degradation of the NHS ester is a competing reaction whose rate increases with pH. The maleimide group is more stable than the NHS-ester group but will slowly hydrolyze and also lose its reaction specificity for sulfhydryls at pH values > 7.5. For these reasons, conjugation experiments involving these cross-linkers are usually performed at pH 7.2-7.5, with the NHS-ester (amine-targeted) reaction being accomplished before or simultaneous with the maleimide (sulfhydryl-targeted) reaction.

6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Nanjing Habo Medical Technology Co., Ltd.
Tel
025-85760892 13376090521
Fax
025-85766769
Email
sales@habotech.com
Country
China
ProdList
999
Advantage
60
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14443
Advantage
57
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
4550
Advantage
62
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12338
Advantage
58
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28398
Advantage
80
Shanghai Xingui Biotechnology Co., Ltd.
Tel
17501653713 17501653715
Email
xingui2022@126.com
Country
China
ProdList
10033
Advantage
58
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400-6387771-6038 18902104717
Email
sales@heowns.com
Country
China
ProdList
20506
Advantage
60
More
Less

View Lastest Price from 6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER 215312-86-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER 215312-86-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08
Career Henan Chemical Co
Product
215312-86-0 215312-86-0
Price
US $1.00/KG
Min. Order
1KG
Purity
≥98%
Supply Ability
200KG
Release date
2019-08-30

215312-86-0, 6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTERRelated Search:


  • 6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER
  • N-(E-MALEIMIDOCAPROYLOXY)-SULFOSUCCINIMIDE
  • N-(E-MALEIMIDOCAPROYLOXY)SULPHOSUCCINIMIDE
  • N-[EPSILON-MALEIMIDOCAPROYLOXY]SULFOSUCCINIMIDE ESTER
  • SULPHO EMCS
  • SULFO-EMCS
  • 6-Maleimidocaproic acid sulfo-NHS
  • 1-[[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]oxy]-2,5-dioxo-3-pyrrolidinesulfonic Acid SodiuM Salt
  • N-(ε-MaleiMidocaproyloxy)sulfosucciniMide ester(Sulfo-EMCS)
  • N-([ε-Maleimidocaproyloxy)sulfosuccinimide ester
  • Sulfo-EMCS N-([ε-Maleimidocaproyloxy)sulfosuccinimide ester
  • Sodium 1-((6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl)oxy)-2,5-dioxopyrrolidine-3-sulfonate
  • 6-Maleimidocaproic Acid Sulfo-N-Succinimidyl Ester Sodium Salt
  • Sulfo-N-Succinimidyl 6-Maleimidocaproate Sodium Salt
  • 6-Maleimidocaproic acid sulfo-NHS (sodium)
  • 215312-86-0
  • C14H16N2O9S
  • C14H15N2O9SNa
  • C14H15N2NaO9S
  • Proteomics and Protein Expression
  • Protein Modification
  • Proteomics
  • Organic Building Blocks
  • Cyclic Imides
  • Crosslinking
  • Heterobifunctional Cross-Linking Reagents
  • BioChemical
  • Building Blocks
  • Carbonyl Compounds
  • Cross Linking Reagents
  • MTS & Sulfhydryl Active Reagents
  • Maleimide Derivatives
  • heteroXlink
  • 1