ChemicalBook > CAS DataBase List > N-Succinimidyl 6-maleimidohexanoate

N-Succinimidyl 6-maleimidohexanoate

Product Name
N-Succinimidyl 6-maleimidohexanoate
CAS No.
55750-63-5
Chemical Name
N-Succinimidyl 6-maleimidohexanoate
Synonyms
2,5-dioxopyrrolidin-1-yl 6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoate;EMCS;MCOSU;6-maleimidohexanoic acid N-hydroxylsuccinimide ester;6-MALEIMIDOCAPROIC ACID N-SUCCINIMIDYL ESTER;6-Maleimidohexanoic acid N-hydroxysuccinimide ester;(2,5-Dioxopyrrolidin-1-yl) 6-(2,5-dioxopyrrol-1-yl)hexanoate;EMCS Crosslinker;maleimide-(CH2)5-NHS;NHS-(CH2)5-Mal (EMCS)
CBNumber
CB8212960
Molecular Formula
C14H16N2O6
Formula Weight
308.29
MOL File
55750-63-5.mol
More
Less

N-Succinimidyl 6-maleimidohexanoate Property

Melting point:
70-73 °C(lit.)
Boiling point:
480.6±47.0 °C(Predicted)
Density 
1.40±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
chloroform: 100mg/mL
form 
powder
pka
-2.21±0.20(Predicted)
color 
Off-white to pale brown
Sensitive 
Light & Moisture Sensitive & Hygroscopic
BRN 
1499815
InChI
InChI=1S/C14H16N2O6/c17-10-5-6-11(18)15(10)9-3-1-2-4-14(21)22-16-12(19)7-8-13(16)20/h5-6H,1-4,7-9H2
InChIKey
VLARLSIGSPVYHX-UHFFFAOYSA-N
SMILES
N1(CCCCCC(ON2C(=O)CCC2=O)=O)C(=O)C=CC1=O
CAS DataBase Reference
55750-63-5(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xn,Xi
Risk Statements 
36/37/38-40
Safety Statements 
26-36/37-36
WGK Germany 
3
F 
8-10-21
HS Code 
29280000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
63177
Product name
6-Maleimidohexanoic acid N-hydroxysuccinimide ester
Purity
≥98.0% (HPLC)
Packaging
25mg
Price
$215
Updated
2024/03/01
Sigma-Aldrich
Product number
568600
Product name
6-Maleimidohexanoic acid N-hydroxysuccinimide ester
Purity
98%
Packaging
500mg
Price
$244
Updated
2024/03/01
TCI Chemical
Product number
S0428
Product name
N-Succinimidyl 6-Maleimidohexanoate [Cross-linking Reagent]
Purity
>98.0%(N)
Packaging
1g
Price
$98
Updated
2024/03/01
Alfa Aesar
Product number
H65996
Product name
6-Maleimidocaproic acid N-succinimidyl ester, 95%
Packaging
250mg
Price
$118.65
Updated
2024/03/01
Alfa Aesar
Product number
H65996
Product name
6-Maleimidocaproic acid N-succinimidyl ester, 95%
Packaging
1g
Price
$372.65
Updated
2024/03/01
More
Less

N-Succinimidyl 6-maleimidohexanoate Chemical Properties,Usage,Production

Description

Mal-heptanoic NHS ester contains a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Chemical Properties

White to cream colored crystals

Uses

6-Maleimidohexanoic acid N-hydroxysuccinimide ester can be used in:

  • Synthesis of maleimide-activated carbohydrates for site-specific glycosylation of cysteine-containing peptides and proteins via maleimide-thiol ligation reaction.
  • Synthesis of a glucuronide prodrug of doxorubicin bearing a maleimide side chain as an antitumor agent.
  • Cross-linking oligonucleotides with the amino groups on the substrate to fabricate DNA microarrays.

N-Succinimidyl 6-maleimidohexanoate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

N-Succinimidyl 6-maleimidohexanoate Suppliers

China 243 Europe 2 France 1 Germany 5 India 6 Japan 2 South Korea 1 Switzerland 2 The Netherlands 1 United Kingdom 10 United States 45 Global 318
Suzhou Highfine Biotech Co., Ltd
Tel
0512-68311833 13962195826
Email
wuhao@highfine.com
Country
China
ProdList
1406
Advantage
58
3A SpeedChemical Inc
Tel
21-65679720
Fax
0086-21-5186 1128
Email
service@speedchemical.com
Country
China
ProdList
604
Advantage
55
Shanghai Balmxy Pharmaceutical Co., Ltd
Tel
021-24206007 13764915196
Fax
86-021-23027023
Email
sales@balmxy.com
Country
China
ProdList
6773
Advantage
55
Shandong fen Boyu Biotechnology Co.,LTD
Tel
13356310019 13356310019
Email
boyu2024@163.com
Country
China
ProdList
2702
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Suzhou Highfine Biotech Co., Ltd
Tel
0512-68311833 13962195826
Fax
0512-68417696
Email
wuhao@highfine.com
Country
China
ProdList
499
Advantage
75
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9809
Advantage
59
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
Jinan Trio PharmaTech Co., Ltd.
Tel
+86 (531) 88811783
Fax
+86 (531) 55696010 QQ 1762738062
Email
sales@trio-pharmatech.com (International market)
Country
China
ProdList
1856
Advantage
62
Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
Email
han_yajun@dctc.daicel.com
Country
China
ProdList
7191
Advantage
65
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
ZhengZhou HuaWen Chemical Co.Ltd
Tel
0370-2785118 17550508557
Fax
QQ：3470079902
Email
675141927@qq.com
Country
China
ProdList
3203
Advantage
55
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
meilunui@163.com
Country
China
ProdList
4727
Advantage
58
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4940
Advantage
60
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9462
Advantage
58
Nanjing Norris-Pharm Technology Co., Ltd
Tel
13901585132
Fax
+86-25-52131256
Email
799750417@qq.com
Country
China
ProdList
8878
Advantage
55
Shenzhen HwaGen Pharmaceutical Co.,Ltd
Tel
18927339850
Fax
0752-5319394
Email
xiaodong.shi@rafflespt.com
Country
China
ProdList
237
Advantage
58
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
18017383231 18017383231
Fax
qq：2817624287
Email
lyh_antaeus@163.com
Country
China
ProdList
9347
Advantage
55
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Shanghai Sheepchem Co., Ltd.
Tel
+86 (21) 6715-7650
Fax
+86 (21) 6715-7651
Email
sheepchem@163.com
Country
China
ProdList
994
Advantage
60
Bsisun HK Imoprt And Export Company Limited
Tel
+86-18068513926
Fax
0086-519-85153711
Country
China
ProdList
1277
Advantage
55
Shanghai Witofly Chemical Co.,Ltd
Tel
Email
sales@witofly.com
Country
China
ProdList
2864
Advantage
52
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
+86-28-85122536 85324413
Fax
+86-28-85326443
Email
market@astatech.cn
Country
China
ProdList
8026
Advantage
55
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Tianjin Chempharmatech Co.,Ltd.
Tel
022-66211079 13212288319
Fax
qq1405432731
Email
sales@chempharmatech.com
Country
China
ProdList
869
Advantage
55
Hygeia (Chengdu) pharmaceutical technique Co., Ltd
Tel
028-84502008 13568869383
Fax
028-66476329
Email
sales@hygeiapharm.com
Country
China
ProdList
298
Advantage
55
Suzhou Sino Rare Chemical Co., Ltd.
Tel
0512-62857507
Fax
+86-512-62857507
Email
sales@sinorarechem.com
Country
China
ProdList
965
Advantage
58
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
CBC Bioctech Co.Ltd.
Tel
+86-571-87028636
Fax
+86-571-87028636
Email
sales@cnbiochem.com
Country
China
ProdList
26
Advantage
58
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883 15367835770
Fax
0731-82251112
Email
viola@huatengsci.com
Country
China
ProdList
5875
Advantage
58
Shanghai Boka-chem Tech. Inc.
Tel
400-026-1533/(021) 6478-0600
Fax
+86 (21) 6459-2060
Email
sales@bokachem.com
Country
China
ProdList
876
Advantage
58
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
16166
Advantage
55
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-+86-571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
11481
Advantage
59
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Tongling HengYou Biotechnology Co., Ltd.
Tel
021-50426030 13856289449
Fax
021-50426030
Email
2630597085@qq.com
Country
China
ProdList
1889
Advantage
55
Struchem Co., Ltd.
Tel
0512-0512-63009836 15365350169
Fax
0512-63006936
Email
helen@struchem.com
Country
China
ProdList
3984
Advantage
60
Guangzhou Zhiya Chemdrugs Co.,Ltd
Tel
18122150900
Fax
QQ:2869377561
Email
sculk28@163.com
Country
China
ProdList
646
Advantage
55
NovoChemy Ltd.
Tel
86-(0)21-31261262 373522135
Fax
86-(0)21-33250524
Email
sales@novochemy.com
Country
China
ProdList
6498
Advantage
58
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9951
Advantage
56
More
Less

View Lastest Price from N-Succinimidyl 6-maleimidohexanoate manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
N-Succinimidyl 6-maleimidohexanoate 55750-63-5
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1Ton
Release date
2022-10-13
Zhuozhou Wenxi import and Export Co., Ltd
Product
N-Succinimidyl 6-maleimidohexanoate 55750-63-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
N-Succinimidyl 6-maleimidohexanoate 55750-63-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08

55750-63-5, N-Succinimidyl 6-maleimidohexanoateRelated Search:

N-Succinimidyl 3-maleimidopropionate Maleimide O-Phthalimide Hexyl hexanoate Methyl acrylate Succinimide Bismaleimide BUTYL OLEATE Tris(trimethylsilyl)phosphate N-Chlorosuccinimide DIALIFOS 6-Maleimidocaproic acid SMCC crosslinker SULFO-SMCC N-Succinimidyl 6-maleimidohexanoate 6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER MAL-AMCHC-OSU SULPHO-SMCC

  • Mal-heptanoic NHS ester
  • EMCS N-Succinimidyl 6-maleimidohexanoate
  • (2,5-Dioxopyrrolidin-1-yl) 6-(2,5-dioxopyrrol-1-yl)hexanoate
  • 6-Maleimidohexanoic acidN-hydroxysuccinimide ester≥ 98% (HPLC)
  • N-(E-MALEIMIDOCAPROYLOXY)SUCCINIMIDE
  • N-(EPSILON-MALEIMIDOCAPROYLOXY)SUCCINIMIDE
  • N-[EPSILON-MALEIMIDOCAPROYLOXY]SUCCINIMIDE ESTER
  • N-(6-MALEIMIDOCAPROYLOXY)SUCCINIMIDE
  • 2,5-dioxopyrrolidin-1-yl 6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoate
  • 6-MaleiMidocaproic acid NHS
  • 6-MaleiMidohexanoic acid N-hydroxysucciniMide este
  • EMCS Crosslinker
  • N-Succinimidyl 6-maleimidohexanoate 6-Maleimidohexanoic acid N-hydroxysuccinimide ester Mcosu
  • 6-maleimidohexanoic acid N-hydroxylsuccinimide ester
  • N-(EPSILON-MALEIMIDOCAPROYLOXY)SUCCI
  • Maleimide-(CH2)5-COONHS
  • 6-Maleimidohexanoic acid N-hydroxysuccinimide ester (EMCS)
  • N-Succinimidyl 6-maleimidohexanoate(EMCS)
  • 6-Maleimidohexanoic Acid N-hydroxy Succinimidyl Este
  • N-SUCCINIMIDYL 6-MALEIMIDOCAPROATE
  • N-SUCCINIMIDYL 6-MALEIMIDOHEXANOATE
  • EMCS
  • EPSILON-MALEIMIDOCAPROIC ACID N-HYDROXYSUCCINIMIDE ESTER
  • 6-MALEIMIDOCAPROIC ACID N-SUCCINIMIDYL ESTER
  • 6-Maleimidohexanoic acid N-hydroxysuccinimide ester
  • N-SUCCINIMIDYL-6-MALEMIDOCAPROATE, 99%
  • EPISILON-MALEIMIDOCAPROIC ACID N-*HYDROX YSUCCINIMID
  • 6-maleimidohexanoic acid n-succinimidyl ester
  • N-(6-Maleimidocaproyloxy)succinimideN-Succinimidyl-6-maleimidohexanoate
  • 6-Maleimidocaproic acid N-hydroxysuccinimide ester
  • N-Succinimidyl 6-Maleimidohexanoate [Cross-linking Reagent]
  • 6-Maleimidocaproic acid N-succinimidyl ester, N-(ε-Maleimidocaproyloxy)succinimide, N-Succinimidyl 6-maleimidocaproate, EMCS
  • 6-Maleimidohexanoic acid N-hydroxy succinimidyl ester
  • NHS-(CH2)5-Mal (EMCS)
  • MCOSU
  • N-(6-Maleimidocaproyloxy)succinimine
  • N-(ε-Maleimidocaproyloxy)succinimide, N-Succinimidyl 6-maleimidocaproate
  • 6-Maleimidohexanoic acid-NHS ester
  • 1H-Pyrrole-1-hexanoicacid, 2,5-dihydro-2,5-dioxo-, 2,5-dioxo-1-pyrrolidinyl
  • 6-maleimidohexanoic acid N-hydroxylsuccinimide ester, N-succinimidyl-6-maleimidylhexanoate
  • N-(6-Maleimidocaproyloxy)succinimide (EMCS)
  • N-Succinimidyl6-Maleimidohexanoate[Cross-linkingReagent]&gt
  • 1H-Pyrrole-1-hexanoic acid, 2,5-dihydro-2,5-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester
  • N-(epsilon-Maleimidocaproyloxy) Succinimide extrapure, 98%
  • Succinimide ester of 6-(maleimide) caproate
  • Succinimide 6-(maleimide) caproate
  • maleimide-(CH2)5-NHS
  • 55750-63-5
  • N-Substituted Maleimides, Succinimides & Phthalimides
  • N-Substituted Maleimides
  • N-Substituted Succinimides
  • Building Blocks
  • Carbonyl Compounds
  • Chemical Synthesis
  • Cyclic Imides
  • Organic Building Blocks
  • N-Substituted Maleimides
  • N-Substituted Maleimides, Succinimides & Phthalimides