ChemicalBook > CAS DataBase List > N-Succinimidyl 6-maleimidohexanoate

N-Succinimidyl 6-maleimidohexanoate

Product Name
N-Succinimidyl 6-maleimidohexanoate
CAS No.
55750-63-5
Chemical Name
N-Succinimidyl 6-maleimidohexanoate
Synonyms
2,5-dioxopyrrolidin-1-yl 6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoate;EMCS;MCOSU;6-maleimidohexanoic acid N-hydroxylsuccinimide ester;6-MALEIMIDOCAPROIC ACID N-SUCCINIMIDYL ESTER;6-Maleimidohexanoic acid N-hydroxysuccinimide ester;(2,5-Dioxopyrrolidin-1-yl) 6-(2,5-dioxopyrrol-1-yl)hexanoate;EMCS Crosslinker;maleimide-(CH2)5-NHS;NHS-(CH2)5-Mal (EMCS)
CBNumber
CB8212960
Molecular Formula
C14H16N2O6
Formula Weight
308.29
MOL File
55750-63-5.mol
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N-Succinimidyl 6-maleimidohexanoate Property

Melting point:
70-73 °C(lit.)
Boiling point:
480.6±47.0 °C(Predicted)
Density 
1.40±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
chloroform: 100mg/mL
form 
powder
pka
-2.21±0.20(Predicted)
color 
Off-white to pale brown
Sensitive 
Light & Moisture Sensitive & Hygroscopic
BRN 
1499815
InChI
InChI=1S/C14H16N2O6/c17-10-5-6-11(18)15(10)9-3-1-2-4-14(21)22-16-12(19)7-8-13(16)20/h5-6H,1-4,7-9H2
InChIKey
VLARLSIGSPVYHX-UHFFFAOYSA-N
SMILES
N1(CCCCCC(ON2C(=O)CCC2=O)=O)C(=O)C=CC1=O
CAS DataBase Reference
55750-63-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
36/37/38-40
Safety Statements 
26-36/37-36
WGK Germany 
3
F 
8-10-21
HS Code 
29280000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
63177
Product name
6-Maleimidohexanoic acid N-hydroxysuccinimide ester
Purity
≥98.0% (HPLC)
Packaging
25mg
Price
$215
Updated
2024/03/01
Sigma-Aldrich
Product number
568600
Product name
6-Maleimidohexanoic acid N-hydroxysuccinimide ester
Purity
98%
Packaging
500mg
Price
$244
Updated
2024/03/01
TCI Chemical
Product number
S0428
Product name
N-Succinimidyl 6-Maleimidohexanoate [Cross-linking Reagent]
Purity
>98.0%(N)
Packaging
1g
Price
$98
Updated
2024/03/01
Alfa Aesar
Product number
H65996
Product name
6-Maleimidocaproic acid N-succinimidyl ester, 95%
Packaging
250mg
Price
$118.65
Updated
2024/03/01
Alfa Aesar
Product number
H65996
Product name
6-Maleimidocaproic acid N-succinimidyl ester, 95%
Packaging
1g
Price
$372.65
Updated
2024/03/01
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N-Succinimidyl 6-maleimidohexanoate Chemical Properties,Usage,Production

Description

Mal-heptanoic NHS ester contains a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Chemical Properties

White to cream colored crystals

Uses

6-Maleimidohexanoic acid N-hydroxysuccinimide ester can be used in:

  • Synthesis of maleimide-activated carbohydrates for site-specific glycosylation of cysteine-containing peptides and proteins via maleimide-thiol ligation reaction.
  • Synthesis of a glucuronide prodrug of doxorubicin bearing a maleimide side chain as an antitumor agent.
  • Cross-linking oligonucleotides with the amino groups on the substrate to fabricate DNA microarrays.

N-Succinimidyl 6-maleimidohexanoate Preparation Products And Raw materials

Raw materials

Preparation Products

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N-Succinimidyl 6-maleimidohexanoate Suppliers

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View Lastest Price from N-Succinimidyl 6-maleimidohexanoate manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
N-Succinimidyl 6-maleimidohexanoate 55750-63-5
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1Ton
Release date
2022-10-13
Zhuozhou Wenxi import and Export Co., Ltd
Product
N-Succinimidyl 6-maleimidohexanoate 55750-63-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
N-Succinimidyl 6-maleimidohexanoate 55750-63-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08

55750-63-5, N-Succinimidyl 6-maleimidohexanoateRelated Search:

N-Succinimidyl 3-maleimidopropionate Maleimide O-Phthalimide Hexyl hexanoate Methyl acrylate Succinimide Bismaleimide BUTYL OLEATE Tris(trimethylsilyl)phosphate N-Chlorosuccinimide DIALIFOS 6-Maleimidocaproic acid SMCC crosslinker SULFO-SMCC N-Succinimidyl 6-maleimidohexanoate 6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER MAL-AMCHC-OSU SULPHO-SMCC

  • Mal-heptanoic NHS ester
  • EMCS N-Succinimidyl 6-maleimidohexanoate
  • (2,5-Dioxopyrrolidin-1-yl) 6-(2,5-dioxopyrrol-1-yl)hexanoate
  • 6-Maleimidohexanoic acidN-hydroxysuccinimide ester≥ 98% (HPLC)
  • N-(E-MALEIMIDOCAPROYLOXY)SUCCINIMIDE
  • N-(EPSILON-MALEIMIDOCAPROYLOXY)SUCCINIMIDE
  • N-[EPSILON-MALEIMIDOCAPROYLOXY]SUCCINIMIDE ESTER
  • N-(6-MALEIMIDOCAPROYLOXY)SUCCINIMIDE
  • 2,5-dioxopyrrolidin-1-yl 6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoate
  • 6-MaleiMidocaproic acid NHS
  • 6-MaleiMidohexanoic acid N-hydroxysucciniMide este
  • EMCS Crosslinker
  • N-Succinimidyl 6-maleimidohexanoate 6-Maleimidohexanoic acid N-hydroxysuccinimide ester Mcosu
  • 6-maleimidohexanoic acid N-hydroxylsuccinimide ester
  • N-(EPSILON-MALEIMIDOCAPROYLOXY)SUCCI
  • Maleimide-(CH2)5-COONHS
  • 6-Maleimidohexanoic acid N-hydroxysuccinimide ester (EMCS)
  • N-Succinimidyl 6-maleimidohexanoate(EMCS)
  • 6-Maleimidohexanoic Acid N-hydroxy Succinimidyl Este
  • N-SUCCINIMIDYL 6-MALEIMIDOCAPROATE
  • N-SUCCINIMIDYL 6-MALEIMIDOHEXANOATE
  • EMCS
  • EPSILON-MALEIMIDOCAPROIC ACID N-HYDROXYSUCCINIMIDE ESTER
  • 6-MALEIMIDOCAPROIC ACID N-SUCCINIMIDYL ESTER
  • 6-Maleimidohexanoic acid N-hydroxysuccinimide ester
  • N-SUCCINIMIDYL-6-MALEMIDOCAPROATE, 99%
  • EPISILON-MALEIMIDOCAPROIC ACID N-*HYDROX YSUCCINIMID
  • 6-maleimidohexanoic acid n-succinimidyl ester
  • N-(6-Maleimidocaproyloxy)succinimideN-Succinimidyl-6-maleimidohexanoate
  • 6-Maleimidocaproic acid N-hydroxysuccinimide ester
  • N-Succinimidyl 6-Maleimidohexanoate [Cross-linking Reagent]
  • 6-Maleimidocaproic acid N-succinimidyl ester, N-(ε-Maleimidocaproyloxy)succinimide, N-Succinimidyl 6-maleimidocaproate, EMCS
  • 6-Maleimidohexanoic acid N-hydroxy succinimidyl ester
  • NHS-(CH2)5-Mal (EMCS)
  • MCOSU
  • N-(6-Maleimidocaproyloxy)succinimine
  • N-(ε-Maleimidocaproyloxy)succinimide, N-Succinimidyl 6-maleimidocaproate
  • 6-Maleimidohexanoic acid-NHS ester
  • 1H-Pyrrole-1-hexanoicacid, 2,5-dihydro-2,5-dioxo-, 2,5-dioxo-1-pyrrolidinyl
  • 6-maleimidohexanoic acid N-hydroxylsuccinimide ester, N-succinimidyl-6-maleimidylhexanoate
  • N-(6-Maleimidocaproyloxy)succinimide (EMCS)
  • N-Succinimidyl6-Maleimidohexanoate[Cross-linkingReagent]&gt
  • 1H-Pyrrole-1-hexanoic acid, 2,5-dihydro-2,5-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester
  • N-(epsilon-Maleimidocaproyloxy) Succinimide extrapure, 98%
  • Succinimide ester of 6-(maleimide) caproate
  • Succinimide 6-(maleimide) caproate
  • maleimide-(CH2)5-NHS
  • 55750-63-5
  • N-Substituted Maleimides, Succinimides & Phthalimides
  • N-Substituted Maleimides
  • N-Substituted Succinimides
  • Building Blocks
  • Carbonyl Compounds
  • Chemical Synthesis
  • Cyclic Imides
  • Organic Building Blocks
  • N-Substituted Maleimides
  • N-Substituted Maleimides, Succinimides & Phthalimides