2-BROMO-1-IODO-4-TRIFLUOROMETHYL-BENZENE
- Product Name
- 2-BROMO-1-IODO-4-TRIFLUOROMETHYL-BENZENE
- CAS No.
- 481075-58-5
- Chemical Name
- 2-BROMO-1-IODO-4-TRIFLUOROMETHYL-BENZENE
- Synonyms
- 3-Bromo-4-iodobenzotrifluoride;3-bromo-4-iodo-trifluoromethylbenzene;2-Bromo-4-(trifluoromethyl)iodobenzene;2-BROMO-1-IODO-4-TRIFLUOROMETHYL-BENZENE;Benzene, 2-bromo-1-iodo-4-(trifluoromethyl)-;2-Bromo-1-iodo-4-(trifluoromethyl)benzene, 3-Bromo-4-iodo-alpha,alpha,alpha-trifluorotoluene
- CBNumber
- CB6832704
- Molecular Formula
- C7H3BrF3I
- Formula Weight
- 350.9
- MOL File
- 481075-58-5.mol
2-BROMO-1-IODO-4-TRIFLUOROMETHYL-BENZENE Property
- Melting point:
- 36-38.5℃ (ethanol )
- Boiling point:
- 236.9±40.0℃ (760 Torr)
- Density
- 2.176±0.06 g/cm3 (20 ºC 760 Torr)
- Flash point:
- 97.1±27.3℃
- storage temp.
- 2-8°C(protect from light)
- form
- fused solid
- color
- Peach/faint orange
Safety
- HS Code
- 2903998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H227Combustible liquid
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B685253
- Product name
- 2-Bromo-1-iodo-4-(trifluoromethyl)benzene
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- B685253
- Product name
- 2-Bromo-1-iodo-4-(trifluoromethyl)benzene
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- HCH0065907
- Product name
- 2-BROMO-1-IODO-4-TRIFLUOROMETHYL-BENZENE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $902.29
- Updated
- 2021/12/16
- Product number
- HCH0065907
- Product name
- 2-BROMO-1-IODO-4-TRIFLUOROMETHYL-BENZENE
- Purity
- 95.00%
- Packaging
- 25G
- Price
- $1449.24
- Updated
- 2021/12/16
- Product number
- FB46543
- Product name
- 3-Bromo-4-iodobenzotrifluoride
- Packaging
- 1g
- Price
- $60
- Updated
- 2021/12/16
2-BROMO-1-IODO-4-TRIFLUOROMETHYL-BENZENE Chemical Properties,Usage,Production
Synthesis
7681-11-0
57946-63-1
481075-58-5
The general procedure for the synthesis of 3-bromo-4-iodobenzotrifluoride from 2-bromo-4-(trifluoromethyl)aniline and potassium iodide was as follows: 2-bromo-4-(trifluoromethyl)aniline (3.00 g, 12.50 mmol) and concentrated hydrochloric acid (15 mL) were added to a solvent mixture of acetonitrile (30 mL) and water (10 mL), and cooled to -10°C. At -10°C, a slow solution of sodium nitrite (0.95 g, 13.75 mmol) in water (5 mL) was added dropwise. The resulting reaction mixture was stirred at -10°C for 30 minutes, then a solution of potassium iodide (2.49 g, 15.00 mmol) in water (5 mL) was added and stirring was continued for 2 hours, then the reaction mixture was allowed to slowly warm to room temperature and reacted overnight. Upon completion of the reaction, saturated sodium bicarbonate solution (30 mL) was added to the reaction mixture and extracted with dichloromethane (50 mL x 3). The organic phases were combined and washed sequentially with saturated sodium thiosulfate solution (30 mL) and saturated brine (30 mL). The organic phase was separated, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The resulting residue was purified by silica gel column chromatography (petroleum ether as eluent) to afford 3-bromo-4-iodobenzotrifluoride as a yellow oily liquid (3.95 g, 90.0% yield).
References
[1] Patent: CN105348204, 2016, A. Location in patent: Paragraph 0386; 0387; 0388
2-BROMO-1-IODO-4-TRIFLUOROMETHYL-BENZENE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-BROMO-1-IODO-4-TRIFLUOROMETHYL-BENZENE manufacturers
- Product
- 3-BroMo-4-iodobenzotrifluoride 481075-58-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 10mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-13