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Masoprocol

Product Name
Masoprocol
CAS No.
27686-84-6
Chemical Name
Masoprocol
Synonyms
CHX-100;masoprocol;NORHYDROGUAIARETICACID;Masoprocol(nordihydroguaiaretic);meso-4,4'-(2,3- Dimethyltetramethylene)dipyrocatechol;(R*,S*)-4,4'-(2,3-dimethylbutane-1,4-diyl)bispyrocatechol;4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]benzene-1,2-diol;4,4'-((2R,3S)-2,3-DiMethylbutane-1,4-diyl)bis(benzene-1,2-diol);4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyrocatechol;rel-4,4'-((2R,3S)-2,3-Dimethylbutane-1,4-diyl)bis(benzene-1,2-diol)
CBNumber
CB6855231
Molecular Formula
C18H22O4
Formula Weight
302.36
MOL File
27686-84-6.mol
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Masoprocol Property

Melting point:
185.5°C
Boiling point:
526.5±45.0 °C(Predicted)
Density 
1.241±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
form 
Solid
pka
9.56±0.10(Predicted)
color 
Off-white to light yellow
LogP
3.710 (est)
EPA Substance Registry System
1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-, (R*,S*)- (27686-84-6)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FB151770
Product name
1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-, (r*,s*)-
Packaging
2mg
Price
$59
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB151770
Product name
1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-, (r*,s*)-
Packaging
5mg
Price
$118
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB151770
Product name
1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-, (r*,s*)-
Packaging
10mg
Price
$205
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB151770
Product name
1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-, (r*,s*)-
Packaging
25mg
Price
$409
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0001379
Product name
MASOPROCOL
Purity
95.00%
Packaging
500MG
Price
$434
Updated
2021/12/16
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Masoprocol Chemical Properties,Usage,Production

Description

Masoprocol is a lipoxygenase inhibitor launched as a topical agent for the treatment of solar or actinic keratoses. It is the first new topical treatment for pre-malignant skin lesions introduced in twenty years. Masoprocol is obtained from the Larrea tridentata plant and is also under investigation for the treatment of lung, breast, colon and ovarian cancers.

Originator

Chemex (U.S.A.)

Uses

Antineoplastic.

Definition

ChEBI: Masoprocol is the meso-form of nordihydroguaiaretic acid. An antioxidant found in the creosote bush, Larrea divaricata, it is a potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. It also inhibits (though to a lesser extent) formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase. It has a role as an antineoplastic agent, a lipoxygenase inhibitor, a hypoglycemic agent and a metabolite.

brand name

Actinex (University Of Arizonia Cancer Center).

Masoprocol Preparation Products And Raw materials

Raw materials

Preparation Products

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Masoprocol Suppliers

BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14055
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65
TargetMol Chemicals Inc.
Tel
+8613564774135
Email
zijue.cai@tsbiochem.com
Country
United States
ProdList
19881
Advantage
58
AmplaChem, Inc.
Tel
--
Fax
--
Email
info@amplacheminc.com
Country
United States
ProdList
428
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50
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
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30
AK Scientific, Inc.
Tel
--
Fax
--
Email
sales@aksci.com
Country
United States
ProdList
6347
Advantage
65
Fine Chem Trading LTD
Tel
--
Fax
--
Email
chemfinder@chemfinder.co.uk
Country
United States
ProdList
1609
Advantage
64

27686-84-6, MasoprocolRelated Search:


  • masoprocol
  • 4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]benzene-1,2-diol
  • (R*,S*)-4,4'-(2,3-dimethylbutane-1,4-diyl)bispyrocatechol
  • Masoprocol(nordihydroguaiaretic)
  • NORHYDROGUAIARETICACID
  • CHX-100
  • meso-4,4'-(2,3- Dimethyltetramethylene)dipyrocatechol
  • 4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]benzene-1,2-diol
  • 4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol
  • 4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyrocatechol
  • 4,4'-((2R,3S)-2,3-DiMethylbutane-1,4-diyl)bis(benzene-1,2-diol)
  • rel-4,4'-((2R,3S)-2,3-Dimethylbutane-1,4-diyl)bis(benzene-1,2-diol)
  • rel-4,4'-((2R,3S)-2,3-Dimethylbutane-1,4-diyl)bis(benzene-1,2-diol)
  • 27686-84-6