2-[[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl-2,2,4,4-d4]amino]-ethanesulfonicacid,monosodiumsalt
- Product Name
- 2-[[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl-2,2,4,4-d4]amino]-ethanesulfonicacid,monosodiumsalt
- CAS No.
- 2410279-93-3
- Chemical Name
- 2-[[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl-2,2,4,4-d4]amino]-ethanesulfonicacid,monosodiumsalt
- Synonyms
- Sodium taurocholate-[D4;Taurocholic acid-d4 (sodium);D4-Taurocholic Acid Sodium Salt;2H4]-Taurocholic Acid Sodium Salt;Taurocholic acid, sodium salt (2,2,4,4-D?, 98%);TAUROCHOLICACID,SODIUMSALT(2,2,4,4-D4) IN METHANOL;Taurocholic acid, sodium salt (2,2,4,4-D?, 98%) 100 μg/mL in methanol;2-[[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl-2,2,4,4-d4]amino]-ethanesulfonicacid,monosodiumsalt;Ethanesulfonic acid, 2-[[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl-2,2,4,4-d4]amino]-, sodium salt (1:1)
- CBNumber
- CB69082449
- Molecular Formula
- C26H41D4NO7S.Na
- Formula Weight
- 542.72
- MOL File
- 2410279-93-3.mol
2-[[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl-2,2,4,4-d4]amino]-ethanesulfonicacid,monosodiumsalt Property
- storage temp.
- Store at -20°C
- solubility
- DMF: 25 mg/mL,DMSO: 20 mg/mL,Ethanol: 2 mg/mL,PBS (pH 7.2): 3 mg/mL
- form
- A solid
- color
- White to off-white
- CAS Number Unlabeled
- 145-42-6
Safety
- WGK Germany
- WGK 2
- Storage Class
- 3 - Flammable liquids
- Hazard Classifications
- Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Flam. Liq. 2
STOT SE 1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H370Causes damage to organs
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
N-Bromosuccinimide Price
- Product number
- 21891
- Product name
- Taurocholic Acid-d4 (sodium salt)
- Purity
- ≥99% deuterated forms (d<sub>1</sub>-d<sub>4</sub>)
- Packaging
- 500μg
- Price
- $61
- Updated
- 2024/03/01
- Product number
- 21891
- Product name
- TaurocholicAcid-d4(sodiumsalt)
- Purity
- ≥99%deuteratedforms(d<sub>1</sub>-d<sub>4</sub>)
- Packaging
- 1mg
- Price
- $112
- Updated
- 2024/03/01
- Product number
- 21891
- Product name
- TaurocholicAcid-d4(sodiumsalt)
- Purity
- ≥99%deuteratedforms(d<sub>1</sub>-d<sub>4</sub>)
- Packaging
- 5mg
- Price
- $468
- Updated
- 2024/03/01
2-[[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl-2,2,4,4-d4]amino]-ethanesulfonicacid,monosodiumsalt Chemical Properties,Usage,Production
Description
Taurocholic acid-d4 (TCA-d4) is intended for use as an internal standard for the quantification of TCA by GC- or LC-MS. TCA is a taurine-conjugated form of the primary bile acid cholic acid . Serum levels of TCA are decreased in patients with Crohn’s disease and those with ulcerative colitis with no extraintestinal manifestations, but are increased in patients with ulcerative colitis accompanied by hepatobiliary disease.
Uses
Taurocholic acid-d4 (sodium) is the deuterium labeled Taurocholic acid. Taurocholic acid (N-Choloyltaurine) is a bile acid involved in the emulsification of fats.
References
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Mooranian A, et al. The effect of a tertiary bile acid, taurocholic acid, on the morphology and physical characteristics of microencapsulated probucol: potential applications in diabetes: a characterization study. Drug Deliv Transl Res. 2015 Oct;5(5):511-22. DOI:10.1007/s13346-015-0248-9
2-[[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl-2,2,4,4-d4]amino]-ethanesulfonicacid,monosodiumsalt Preparation Products And Raw materials
Raw materials
Preparation Products
2-[[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl-2,2,4,4-d4]amino]-ethanesulfonicacid,monosodiumsalt Suppliers
- Tel
- 19138486554; 18108108965
- Fax
- 0575-89298961
- sales@artisbio.com
- Country
- China
- ProdList
- 2100
- Advantage
- 58
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 18818260767
- Fax
- QQ 3610331285
- sales@chemegen.com
- Country
- China
- ProdList
- 11218
- Advantage
- 58
- Tel
- 18502138905
- shanpel@anpel.com.cn
- Country
- China
- ProdList
- 9611
- Advantage
- 58
- Tel
- 13540909846 13882008651
- 3848291069@qq.com
- Country
- China
- ProdList
- 3001
- Advantage
- 58
- Tel
- 021-64400900 15800436310
- bessey@reertech.com
- Country
- China
- ProdList
- 4105
- Advantage
- 58
- Tel
- 02151600108 13062666369
- info@isotopechem.com
- Country
- China
- ProdList
- 4997
- Advantage
- 58
- Tel
- 021-58000709 15900491054
- info@scrbio.com
- Country
- China
- ProdList
- 9883
- Advantage
- 58
- Tel
- 13720134139 086-15871494362 13720134139
- orders@jknbiochem.com
- Country
- China
- ProdList
- 6974
- Advantage
- 58
- Tel
- 021-65675885 18964387627
- customer_service@efebio.com
- Country
- China
- ProdList
- 11973
- Advantage
- 58