Application
ChemicalBook > CAS DataBase List > 6-Chloro-2,3-diaminopyridine

6-Chloro-2,3-diaminopyridine

Application
Product Name
6-Chloro-2,3-diaminopyridine
CAS No.
40851-95-4
Chemical Name
6-Chloro-2,3-diaminopyridine
Synonyms
6-Chloropyridine-2,3-diamin;6-chloro-2,3-PyridinediaMine;6-Chloro-2,3-diaminopyridine;2,3-PyridinediaMine, 6-chloro-;2,3-Diamino-6-chloropyridine ,97%;6-chloro-pyridine-2,3-diyldiamine;6-Chloro-2,3-diaminopyridine ISO 9001：2015 REACH;2,3-Diamino-6-chloropyridineNew
CBNumber
CB6947716
Molecular Formula
C5H6ClN3
Formula Weight
143.57
MOL File
40851-95-4.mol
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6-Chloro-2,3-diaminopyridine Property

Melting point:
132.0 to 136.0 °C
Boiling point:
360.2±37.0 °C(Predicted)
Density 
1.447±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
2.69±0.50(Predicted)
form 
powder to crystal
color 
White to Brown to Dark purple
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38-42/43-33-23/24/25
Safety Statements 
22-36/37-45-37-28
RIDADR 
2811
WGK Germany 
3
HazardClass 
6.1
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
777641
Product name
2,3-Diamino-6-chloropyridine
Purity
97%
Packaging
1g
Price
$67.59
Updated
2025/07/31
TCI Chemical
Product number
D4765
Product name
2,3-Diamino-6-chloropyridine
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$81
Updated
2025/07/31
TRC
Product number
C351020
Product name
6-Chloropyridine-2,3-diamine
Packaging
100mg
Price
$45
Updated
2021/12/16
TRC
Product number
C351020
Product name
6-Chloropyridine-2,3-diamine
Packaging
250mg
Price
$55
Updated
2021/12/16
Matrix Scientific
Product number
074602
Product name
6-Chloro-2,3-diaminopyridine
Purity
95+%
Packaging
1g
Price
$85
Updated
2021/12/16
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6-Chloro-2,3-diaminopyridine Chemical Properties,Usage,Production

Application

6-Chloro-2,3-diaminopyridine is an organic synthesis intermediate and a pharmaceutical intermediate that can be used in laboratory research and development processes as well as in chemical and pharmaceutical synthesis.

Chemical Properties

Dark green solid

Synthesis

146015-42-1

40851-95-4

6-Chloro-2-nitropyridin-3-amine (E-23) (8.8 g, 51 mmol, 1.0 eq.) was used as a raw material and mixed with Ruanne nickel (0.88 g) in methanol (100 mL). The reaction mixture was stirred at room temperature for 24 hours under hydrogen atmosphere. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated under vacuum to afford the target product 6-chloropyridine-2,3-diamine (E-24) (7 g, 95.6% yield) as a pale white solid. The product was detected by ESI-MS, m/z: 144.05 [M + H]+.

References

[1] Patent: WO2011/149937, 2011, A1. Location in patent: Page/Page column 40; 41; 84
[2] Patent: WO2013/78441, 2013, A1. Location in patent: Paragraph 00143; 00326
[3] Patent: WO2014/151147, 2014, A1. Location in patent: Paragraph 00641
[4] Patent: US2015/30588, 2015, A1. Location in patent: Page/Page column 66
[5] Patent: US9295673, 2016, B2. Location in patent: Page/Page column 341; 342

6-Chloro-2,3-diaminopyridine Preparation Products And Raw materials

Raw materials

Stannous chloride dihydrate 2-Amino-6-chloro-3-nitropyridine Acetic anhydride tert-Butanol Sodium borohydride Ethyl acetate PETROLEUM ETHER

Preparation Products

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6-Chloro-2,3-diaminopyridine Suppliers

Americas 1 China 161 Europe 1 Germany 1 India 5 Japan 1 United Kingdom 2 United States 23 Global 195
TCI Chemicals (India) Pvt. Ltd.
Tel
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Fax
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Email
sales-in@tcichemicals.com
Country
India
ProdList
6768
Advantage
58
Reax Chemicals
Tel
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Fax
--
Country
India
ProdList
4217
Advantage
58
Sachin Chemicals
Tel
--
Fax
--
Email
sachinchemicals@gmail.com
Country
India
ProdList
140
Advantage
58
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
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View Lastest Price from 6-Chloro-2,3-diaminopyridine manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
6-Chloropyridine-2,3-diamine 40851-95-4
Price
US $3.00-9.00/KG
Min. Order
0.1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2025-06-26
Shaanxi Dideu Medichem Co. Ltd
Product
6-Chloro-2,3-diaminopyridine 40851-95-4
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-04-30
Career Henan Chemical Co
Product
6-Chloro-2,3-diaminopyridine 40851-95-4
Price
US $1.00/kg
Min. Order
1kg
Purity
98%min
Supply Ability
500kg
Release date
2018-12-20

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