Rutaecarpine

Product Name: Rutaecarpine
CAS No.: 20575-76-2
Chemical Name: Rutaecarpine
Synonyms: Ai3-51108;Nsc 255317;Brn 2116874;Rutaecarpine;3,3'-HEXAMETHYLENEBIS(1,1-DIMETHYLUREA);1,1'-Hexamethylenebis[3,3-dimethylurea];Urea, 1,1'-hexamethylenebis(3,3-dimethyl-;1,1-(Hexane-1,6-diyl)bis(3,3-dimethylurea);N,N''-1,6-Hexanediylbis[N',N'-dimethylurea];Urea, N,N''-1,6-hexanediylbis[N',N'-dimethyl-
CBNumber: CB6975933
Molecular Formula: C12H26N4O2
Formula Weight: 258.36
MOL File: 20575-76-2.mol

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Rutaecarpine Property

Boiling point:: 512.3±33.0 °C(Predicted)
Density: 1.021±0.06 g/cm3(Predicted)
pka: 13.98±0.46(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S590355
Product name: 3,3'-HEXAMETHYLENEBIS(1,1-DIMETHYLUREA)
Purity: Aldrich
Packaging: 250mg
Price: $29.8
Updated: 2024/03/01

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Rutaecarpine Chemical Properties,Usage,Production

Biological Functions

Rutaecarpine also inhibits accumulation of macrophages and cholesterol in atherosclerotic lesions and increases cholesterol excretion in other animal models. Additionally, rutaecarpine inhibits hypoxia-induced production of ROS and lactate dehydrogenase and suppresses apoptosis in myocardiocytes. In other cellular models, rutaecarpine decreases corticosterone production, potentially through inhibition of cAMP, 3β-hydroxysteroid dehydrogenase, and 11β-hydroxylase activity.

Biological Activity

Rutaecarpine is an indoloquinazoline alkaloid originally found in Evodia; it exhibits anti-inflammatory, anti-atherosclerotic, cardioprotective, anorexigenic, and anti-obesity activities. Rutaecarpine inhibits COX-2 and also decreases food intake, weight gain, and serum glucose, leptin, and insulin levels in vivo by inhibiting expression of neuropeptide Y and AgRP.

Mechanism of action

Rutaecarpine also inhibits production of ROS, NO, and iNOS, potentially through inhibition of NADPH oxidase. In macrophages, rutaecarpine inhibits arachidonic acid release and decreases production of prostaglandin E2 (PGE2); in other in vitro models, it inhibits collagen-stimulated formation of thromboxane B2 and inosine monophosphate.

Rutaecarpine Preparation Products And Raw materials

Raw materials

Preparation Products

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Rutaecarpine Suppliers

China 35 Germany 1 India 1 United States 5 Global 42

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 400-400-400-9004166 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52712
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: 571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: CHINA
ProdList: 52867
Advantage: 58

Dideu Industries Group Limited

Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Country: China
ProdList: 29016
Advantage: 58

career henan chemical co

Tel: +86-0371-86658258 15093356674;
Fax: 0086-371-86658258
Email: factory@coreychem.com
Country: China
ProdList: 29826
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 55023
Advantage: 58

Shaanxi DIDU pharmaceutical and Chemical Co., Ltd

Tel: 15229059051
Email: 1027@dideu.com
Country: China
ProdList: 9941
Advantage: 58

Shanghai Moqi Biological Technology Co., LTD

Tel: 021-38218169 13341702378
Email: 190129269@qq.com
Country: China
ProdList: 9109
Advantage: 58

cuicheng bio

Tel: 13186333400
Email: m13108465082@163.com
Country: China
ProdList: 886
Advantage: 58

Auonsi (Shanghai) Biology Technology Co., Ltd.

Tel: 400-1107768 15058188853
Fax: 0571-88150696
Email: 478133536@qq.com
Country: China
ProdList: 8555
Advantage: 58

GIHI CHEMICALS CO.,LIMITED

Tel: +8618058761490
Email: info@gihichemicals.com
Country: China
ProdList: 50000
Advantage: 58

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View Lastest Price from Rutaecarpine manufacturers

Career Henan Chemical Co

Product: Rutaecarpine 20575-76-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98% HPLC
Supply Ability: 10 tons
Release date: 2020-02-03

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3-[6-(dimethylcarbamoylamino)hexyl]-1,1-dimethyl-urea

1,1'-Hexamethylenebis[3,3-dimethylurea]

N,N''-1,6-Hexanediylbis[N',N'-dimethylurea]

Rutaecarpine

Ai3-51108

Brn 2116874

Nsc 255317

Urea, 1,1'-hexamethylenebis(3,3-dimethyl-

Urea, N,N''-1,6-hexanediylbis(N',N'-dimethyl- (9ci)

3,3'-HEXAMETHYLENEBIS(1,1-DIMETHYLUREA)

1,1-(Hexane-1,6-diyl)bis(3,3-dimethylurea)

Urea, N,N''-1,6-hexanediylbis[N',N'-dimethyl-

20575-76-2

82-26-4