N,N''-1,6-Hexanediylbis[N',N'-dimethylurea]

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N,N''-1,6-Hexanediylbis[N',N'-dimethylurea]

Product Name: N,N''-1,6-Hexanediylbis[N',N'-dimethylurea]
CAS No.: 20575-76-2
Chemical Name: N,N''-1,6-Hexanediylbis[N',N'-dimethylurea]
Synonyms: Ai3-51108;Nsc 255317;Brn 2116874;3,3'-HEXAMETHYLENEBIS(1,1-DIMETHYLUREA);1,1'-Hexamethylenebis[3,3-dimethylurea];Urea, 1,1'-hexamethylenebis(3,3-dimethyl-;1,1-(Hexane-1,6-diyl)bis(3,3-dimethylurea);N,N''-1,6-Hexanediylbis[N',N'-dimethylurea];1,1'-(Hexane-1,6-diyl)bis(3,3-dimethylurea);Urea, N,N''-1,6-hexanediylbis[N',N'-dimethyl-
CBNumber: CB6975933
Molecular Formula: C12H26N4O2
Formula Weight: 258.36
MOL File: 20575-76-2.mol

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N,N''-1,6-Hexanediylbis[N',N'-dimethylurea] Property

Boiling point:: 512.3±33.0 °C(Predicted)
Density: 1.021±0.06 g/cm3(Predicted)
pka: 13.98±0.46(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S590355
Product name: 3,3'-HEXAMETHYLENEBIS(1,1-DIMETHYLUREA)
Purity: Aldrich
Packaging: 250mg
Price: $29.8
Updated: 2024/03/01

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N,N''-1,6-Hexanediylbis[N',N'-dimethylurea] Chemical Properties,Usage,Production

Biological Functions

Rutaecarpine also inhibits accumulation of macrophages and cholesterol in atherosclerotic lesions and increases cholesterol excretion in other animal models. Additionally, rutaecarpine inhibits hypoxia-induced production of ROS and lactate dehydrogenase and suppresses apoptosis in myocardiocytes. In other cellular models, rutaecarpine decreases corticosterone production, potentially through inhibition of cAMP, 3β-hydroxysteroid dehydrogenase, and 11β-hydroxylase activity.

Biological Activity

Rutaecarpine is an indoloquinazoline alkaloid originally found in Evodia; it exhibits anti-inflammatory, anti-atherosclerotic, cardioprotective, anorexigenic, and anti-obesity activities. Rutaecarpine inhibits COX-2 and also decreases food intake, weight gain, and serum glucose, leptin, and insulin levels in vivo by inhibiting expression of neuropeptide Y and AgRP.

Mechanism of action

Rutaecarpine also inhibits production of ROS, NO, and iNOS, potentially through inhibition of NADPH oxidase. In macrophages, rutaecarpine inhibits arachidonic acid release and decreases production of prostaglandin E2 (PGE2); in other in vitro models, it inhibits collagen-stimulated formation of thromboxane B2 and inosine monophosphate.

N,N''-1,6-Hexanediylbis[N',N'-dimethylurea] Preparation Products And Raw materials

Raw materials

Preparation Products

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N,N''-1,6-Hexanediylbis[N',N'-dimethylurea] Suppliers

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View Lastest Price from N,N''-1,6-Hexanediylbis[N',N'-dimethylurea] manufacturers

Career Henan Chemical Co

Product: Rutaecarpine 20575-76-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98% HPLC
Supply Ability: 10 tons
Release date: 2020-02-03

20575-76-2, N,N''-1,6-Hexanediylbis[N',N'-dimethylurea]Related Search:

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3-[6-(dimethylcarbamoylamino)hexyl]-1,1-dimethyl-urea

1,1'-Hexamethylenebis[3,3-dimethylurea]

N,N''-1,6-Hexanediylbis[N',N'-dimethylurea]

Ai3-51108

Brn 2116874

Nsc 255317

Urea, 1,1'-hexamethylenebis(3,3-dimethyl-

Urea, N,N''-1,6-hexanediylbis(N',N'-dimethyl- (9ci)

3,3'-HEXAMETHYLENEBIS(1,1-DIMETHYLUREA)

1,1-(Hexane-1,6-diyl)bis(3,3-dimethylurea)

Urea, N,N''-1,6-hexanediylbis[N',N'-dimethyl-

1,1'-(Hexane-1,6-diyl)bis(3,3-dimethylurea)

20575-76-2

82-26-4