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Ademethionine Disulfate Tosylate

Product Name
Ademethionine Disulfate Tosylate
CAS No.
97540-22-2
Chemical Name
Ademethionine Disulfate Tosylate
Synonyms
S-Adenosyl-L-methionine disulfate tosylate;AdeMethionine Disulfate Tosylate;S-ADENOSYL-L-METHIONINE DISULFATE P-TOLUENESULFONATE;SAM-T;S-adenosyl-L-methionine disulphate tosylate;fo-1561;SAME-PTS;Ademetionine disulfa;Ademetioninedisulfatetosylat;ADEMETHIONINE SULFATE TOSYLATE
CBNumber
CB7101717
Molecular Formula
C22H34N6O16S4
Formula Weight
766.78
MOL File
97540-22-2.mol
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Ademethionine Disulfate Tosylate Property

Melting point:
>122°C (dec.)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
DMSO (Slightly, Heated), Water (Sparingly)
form 
Solid
color 
White to Pale Yellow
Stability:
Hygroscopic
InChI
InChI=1/C15H22N6O5S.C7H8O3S.2H2O4S/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21;1-6-2-4-7(5-3-6)11(8,9)10;2*1-5(2,3)4/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25);2-5H,1H3,(H,8,9,10);2*(H2,1,2,3,4)/t7-,8+,10+,11+,14+,27?;;;/s3
InChIKey
XDCFCHNAIMYBAZ-DUXZMFTLNA-N
SMILES
S(C1C=CC(C)=CC=1)(O)(=O)=O.S(O)(O)(=O)=O.O[C@@H]1[C@@H]([C@@H](C[S+](C)CC[C@H](N)C(=O)O)O[C@H]1N1C=NC2C(=NC=NC1=2)N)O.S(O)([O-])(=O)=O |&1:17,18,19,25,31,r|
CAS DataBase Reference
97540-22-2(CAS DataBase Reference)
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Safety

Risk Statements 
36/37/38
Safety Statements 
24/25
HS Code 
2934990002
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
16376
Product name
S-(5'-Adenosyl)-L-methionine (sulfate tosylate)
Purity
≥95%
Packaging
50mg
Price
$65
Updated
2021/12/16
Cayman Chemical
Product number
16376
Product name
S-(5'-Adenosyl)-L-methionine (sulfate tosylate)
Purity
≥95%
Packaging
100mg
Price
$117
Updated
2021/12/16
Cayman Chemical
Product number
16376
Product name
S-(5'-Adenosyl)-L-methionine (sulfate tosylate)
Purity
≥95%
Packaging
500mg
Price
$520
Updated
2021/12/16
Usbiological
Product number
295234
Product name
S-Adenosyl-L-methionine Disulfate Tosylate
Packaging
50g
Price
$237
Updated
2021/12/16
TRC
Product number
A280350
Product name
AdemethionineDisulfateTosylate(>90%)
Packaging
500mg
Price
$240
Updated
2021/12/16
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Ademethionine Disulfate Tosylate Chemical Properties,Usage,Production

Chemical Properties

White to off-white powder

Uses

Ademetionine Disulfate Tosylate is the disulfate-tosylate mixed salt of a mixture of diastereoisomers of the ademetionine ions. Ademetionine possesses anti-inflammatory activity and has been used in treatment of chronic liver disease.

Uses

Ademetionine Disulfate Tosylate is used to study the survival time in various damage brain models.

Definition

The density of Ademethionine Disulfate Tosylate is typically between 1.42-1.48 g/cm3. Its unique characteristics make it an ideal compound for various health supplements and pharmaceuticals. The compound is commonly packaged in sealed containers and transported at controlled temperatures to ensure its integrity and purity. It is manufactured through synthetic procedures involving the reaction between adenosine triphosphate (ATP) and methionine. Ademethionine Disulfate Tosylate is typically used for its therapeutic effects, which range from improving liver function to providing relief from depression and arthritis. It is used extensively in treating liver diseases and is known to enhance liver cell regeneration, promote bile flow, and improve overall liver function. SAMe is also known for its anti-inflammatory properties, which make it effective in reducing the symptoms of conditions such as osteoarthritis and depression.

Biological Activity

Studies have shown that S-adenosyl-L-methionine disulfate tosylate salt (SAMe-ST) at concentrations of 0.2 to 5.0 mg/ml protects red blood cells from hypotonic hemolysis, and that this protection is attributed to the SAMe moiety itself, rather than its Sulfate or mesylate moiety. SAMe-ST significantly increased Na+.K(+)-ATPase activity[1].

References

[1] M TSUJI;K O;K Kodama. Protective effects of S-adenosyl-L-methionine against enzyme leakage from cultured hepatocytes and hypotonic hemolysis.[J]. Japanese journal of pharmacology, 1990. DOI:10.1254/jjp.52.45.

Ademethionine Disulfate Tosylate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ademethionine Disulfate Tosylate Suppliers

Belgium 1 Canada 1 China 336 China Hong Kong 1 Germany 3 India 6 United Kingdom 5 United States 21 Global 374
HBCChem, Inc.
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View Lastest Price from Ademethionine Disulfate Tosylate manufacturers

Sinoway Industrial co., ltd.
Product
S-Adenosyl-L-Methionine Disulfate Tosylate 97540-22-2
Price
US $0.00/kg/drum
Min. Order
2kg/drum
Purity
99% up, High Density
Supply Ability
20 tons
Release date
2024-03-04
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Ademetionine disulfate tosylate 97540-22-2
Price
US $0.00/Kg/Bag
Min. Order
1KG
Purity
95.0%~103.0%; USP43
Supply Ability
3000 kg/month
Release date
2021-06-03
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Ademetionine Disulfate Tosylate 97540-22-2
Price
US $120.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10ton
Release date
2024-05-22

97540-22-2, Ademethionine Disulfate TosylateRelated Search:

p-Toluenesulfonic acid Sodium p-toluenesulfonate L-Methionine S-ADENOSYL-L-METHIONINE DL-Methionine Adenosine S-adenosylmethionine ALTRENOGEST Betaine Sorafenib tosylate Sodium xylenesulfonate 4-CHLOROBENZOYLACETONITRILE 5'-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE Glycine Citicoline sodium ATP disodium salt (S)-(-)-2-Methyl-2-propanesulfinamide (S)-2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-3-cyanopropanoic acid

  • SAM-T(S-Adenosyl-5-L-Methionine Tosylate)
  • S-Adenosyl-L-Methionine disulfate tosylate(SAM-T)
  • S-adenisyl-L-Methioninedisulfate-p-toluenesulfonate
  • SAM-T
  • AdeMethionine Disulfate Tosylate
  • S-Adenosyl-L-Methionine Disulfate p-Toluenesulfonate (Mixture of Diastereomers)
  • Ademetionine disulfate tosylate S-Adenosyl-L-methionine disulfate tosylate
  • Ademetionine Disulfate Tosylate (500 mg) (S-Adenosyl-L-Methionine Disulfate Tosylate)
  • S-(5'-Adenosyl)-L-methionine (sulfate tosylate)
  • S-Adenosyl-L-methionine disulfate tosylateUSP, 95.0-105.0% (Assay)
  • Ademetionine Disulfate Tosylate(SAMe)
  • SAM-TAdemetionine disulfate tosylate
  • S-(5'-Adenosyl)-L-methionine (tosylate)
  • 5’-((3-amino-3-carboxypropyl)methylsulfonio)-5’-deoxy-adenosin(s)-adenosinsaltw
  • adenosylmethioninetosylatebis(sulfate
  • fo-1561
  • ith4-methylbenzenesulfonicacid,sulfate(salt)(1:1:2)
  • S-ADENOSYL-L-METHIONINE SULFATE P-TOLUENESULFONATE
  • S-ADENOSYL-L-METHIONINE SULFATE TOSYLATE
  • SAME-PTS
  • S-adenosyl-L-methionine disulphate tosylate
  • S-ADENOSYL-L-METHIONINE DISULFATE P-TOLUENESULFONATE
  • Ademetionine Disulfate Tosylate (500 mg)
  • Ademetionine disulfa
  • 5'-[[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-adenosine disulfate 4-methylbenzenesulfonate
  • Ademetionine disulfate tosylate
  • S-Adenosyl-L-methionine disulfate tosylate
  • ADEMETHIONINE SULFATE TOSYLATE
  • Ademethionine Disulfate Tosylate (&gt
  • Adenosine,5'-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-, sulfate(salt), 4-methylbenzenesulfonate (salt) sulfate (salt) (1:1:1:1)
  • Ademetionine disulfate tosylate USP/EP/BP
  • Ademethionine Disulfate Tosylate (>90%)
  • Ademetioninedisulfatetosylat
  • Manufacturer Supply 99% Bulk S-Adenosyl-L-Dl-Methionine Sam-E CAS 97540-22-2
  • S-Adenosyl-L-methionine Disulfate Tosylate （SAME）
  • ((S)-3-Amino-3-carboxypropyl)(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(methyl)sulfonium hydrogen sulfate 4-methylbenzenesulfonate sulfate
  • S- adenosylmethionine p-toluenesulfonic acid sulfate
  • S-Adenosyl-L-methionine disulf
  • Adenosine, 5'-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-, sulfate, 4-methylbenzenesulfonate sulfate (1:1:1:1)
  • 5'-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-Adenosine sulfate 4-methylbenzenesulfonate sulfate (1:1:1:1)
  • (2S)-2-amino-4-((((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(methyl)sulfonio)butanoate 4-methylbenzenesulfonate bis(sulfate)
  • S-adenosyl-L-methionine disulfate p-toluensulfonate
  • P-Toluenesulfonic acid disulfide adenosine methionine
  • P-Toluenesulfonic Acid Adenosine Sulfate Methionine
  • 5'-[[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-adenosine sulfate 4-methylbenzenesulfonate sulfate (1:1:1:1)
  • SAM e (S-(5-Adenosyl)-L-methionine disulfate tosylate), Methyl donor
  • 97540-22-2
  • C7H8O3SC15H22N6O5S2H2O4S
  • C22H32N6O15S4
  • C22H35N6O16S4
  • C22H36N6O16S4
  • C22H34N6O16S4
  • C15H22N6O5SC7H12O11S2
  • C15H22N6O5S2H2SO4C7H8SO3
  • C15H23N6O5SC7H8O3SHO4SH2O4S
  • API
  • 97540-22-2
  • nutrition supplement