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Dehydrocostus lactone

Product Name
Dehydrocostus lactone
CAS No.
477-43-0
Chemical Name
Dehydrocostus lactone
Synonyms
EPILIGULYL OXIDE;DEHYDROCOSTUNOLIDE;ehydrocostuslactone;DEHYDROCOSTUSLACTONE;dehydrocostiolactone;Costus lactone, dehydro-;Dehydrocostus lactone-RM;DEHYDROCOSTUS LACTONE hplc;Dehydrocostus lactone, >=98%;Dehydrocostuslactone Standard
CBNumber
CB7106297
Molecular Formula
C15H18O2
Formula Weight
230.3
MOL File
477-43-0.mol
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Dehydrocostus lactone Property

Melting point:
57.0 to 61.0 °C
Boiling point:
140-143 °C(Press: 0.5 Torr)
Density 
1.09
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
form 
Solid
color 
White to Off-White
Odor
nutty
optical activity
[α]/D -14.0±3.0°, c = 1 in chloroform
λmax
206nm(MeOH)(lit.)
InChIKey
NETSQGRTUNRXEO-XUXIUFHCSA-N
LogP
1.480 (est)
CAS DataBase Reference
477-43-0(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
HS Code 
29322090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
42575
Product name
Dehydrocostus lactone
Purity
analytical standard
Packaging
10mg
Price
$105
Updated
2024/03/01
TCI Chemical
Product number
D5366
Product name
Dehydrocostus Lactone
Purity
>98.0%(GC)
Packaging
10mg
Price
$81
Updated
2024/03/01
TCI Chemical
Product number
D5366
Product name
Dehydrocostus Lactone
Purity
>98.0%(GC)
Packaging
50mg
Price
$250
Updated
2024/03/01
Cayman Chemical
Product number
18485
Product name
Dehydrocostus lactone
Purity
≥95%
Packaging
5mg
Price
$54
Updated
2024/03/01
Cayman Chemical
Product number
18485
Product name
Dehydrocostus lactone
Purity
≥95%
Packaging
10mg
Price
$78
Updated
2024/03/01
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Dehydrocostus lactone Chemical Properties,Usage,Production

Description

Dehydrocostus lactone is a natural sesquiterpene first isolated from costus root, which is used in traditional medicine. Dehydrocostus lactone has diverse anti-cancer properties in cells and animal models, causing cell cycle arrest, inducing apoptosis, diminishing multidrug resistance, and suppressing angiogenesis in cancer cells. It also has anti-inflammatory actions in cells, including the inhibition of signaling through STAT1 and STAT3.

Description

A guaianolide sesquiterpene lactone extracted from costus oil. Dehydrocostuslactone is one of the components of lactone-mix, with costunolide and alantolactone, used to detect Compositae-sensitive patients.

Uses

Dehydrocostus lactone is the oil extracted from Saussurea lappa is used in perfumery and in the Orient for all kinds of diseases.

Uses

Dehydrocostus Lactone is a compound known to be a growth regulator in plants. Known to affect cell viability and cell cycle distribution it may be useful in the application towards drug-resistant tumors.

Definition

ChEBI: An organic heterotricyclic compound and guaianolide sesquiterpene lactone that is acrylic acid which is substituted at position 2 by a 4-hydroxy-3,8-bis(methylene)decahydoazulen-5-yl group and in which the hydroxy group and the carboxy group have undergone formal condensation to afford the corresponding gamma-lactone.

Contact allergens

A guaianolide sesquiterpene lactone extracted from costus oil. It is one of the components of Lactone mix, with costunolide and alantolactone, used to detect Compositae-sensitive patients.

Dehydrocostus lactone Preparation Products And Raw materials

Raw materials

Preparation Products

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Dehydrocostus lactone Suppliers

Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
Apin Chemicals Limited (UK)
Tel
--
Fax
--
Email
info@apinchemicals.com
Country
United Kingdom
ProdList
6184
Advantage
60
MOLEKULA Ltd.
Tel
--
Fax
--
Email
kevinbanks@molekula.com
Country
United Kingdom
ProdList
6140
Advantage
66
ETA SCIENTIFIC Co.,Ltd
Tel
--
Fax
--
Email
sales@etascientific.com
Country
United Kingdom
ProdList
6090
Advantage
34
Apin Chemicals Ltd.
Tel
--
Fax
--
Email
info@apinchemicals.com
Country
United Kingdom
ProdList
6807
Advantage
42
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View Lastest Price from Dehydrocostus lactone manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
Dehydrocostus Lactone 477-43-0
Price
US $11.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000kg
Release date
2024-08-21
Chongqing Zhihe Biopharmaceutical Co., Ltd.
Product
Dehydrocostus lactone 477-43-0
Price
US $0.00-0.00/kg
Min. Order
0.10000000149011612kg
Purity
≥98%
Supply Ability
20tons
Release date
2024-01-04
Shaanxi Dideu Medichem Co. Ltd
Product
Dehydrocostus lactone 477-43-0
Price
US $30.00-20.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200000KG
Release date
2024-08-06

477-43-0, Dehydrocostus lactoneRelated Search:


  • EPILIGULYL OXIDE
  • DEHYDROCOSTUSLACTONE
  • DEHYDROCOSTUS LACTONE hplc
  • (3aS,6aR,9aR,9bS)-Decahydro-3,6,9-tris(methylene)azuleno[4,5-b]furan-2(3H)-one
  • DEHYDROCOSTUNOLIDE
  • Azuleno[4,5-b]furan-2(3H)-one,decahydro-3,6,9-
  • Costus lactone, dehydro-
  • tris(methylene)-,(3aS,6aR,9aR,9bS)-
  • (3aS)-3,6,9-Tris(methylene)-2,3,3a,4,5,6,6aβ,7,8,9,9aβ,9bα-dodecahydroazuleno[4,5-b]furan-2-one
  • (3aS,6aβ,9aβ,9bα)-Dodecahydro-3,6,9-tris(methylene)azuleno[4,5-b]furan-2-one
  • 3aβ,4,5,6,6aβ,7,8,9,9aβ,9bα-Decahydro-3,6,9-trismethyleneazuleno[4,5-b]furan-2(3H)-one
  • (3aS,6aR,9aR,9bS)-3,6,9-trimethylene-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[4,5-b]furan-2-one
  • (3aS,6aR,9aR,9bS)-3,6,9-trimethylidene-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[4,5-b]furan-2-one
  • Dehydrocostus Lactone 477-43-0
  • [3aS-(3aalpha,6aalpha,9aalpha,9bbeta)]-Decahydro-3,6,9-tris(methylene)-azuleno[4,5-b]furan-2(3H)-one
  • Dehydro-costus lactone (6CI,7CI)
  • Guaia-4(15),10(14),11(13)-trien-12-oic acid, 6alpha-hydroxy-, gamma-lactone
  • Dehydrocostus lactone, >=98%
  • Dehydrocostuslactone, 98%, from Common Vladimiria Root
  • Dehydrocostus Lactone ((-)-Dehydrocostus lactone
  • Dehydrocostuslactone Standard
  • Azuleno[4,5-b]furan-2(3H)-one, decahydro-3,6,9-tris(methylene)-, (3aS,6aR,9aR,9bS)-
  • ehydrocostuslactone
  • (3aS,6aR,9aR,9bS)-3,6,9-Trimethylenedecahydroazuleno[4,5-b]furan-2(9bH)-one
  • (3aS,6aR,9aR,9bS)-3,6,9-Trimethylenedecahydroazuleno[4,5-b]furan-2(3H)-one
  • dehydrocostiolactone
  • Dehydrocostus lactone-RM
  • 477-43-0
  • 447-43-0
  • C15H18O2
  • Sesquiterpenoids
  • Inhibitors
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Heterocycles