Dehydrocostus lactone

Product Name: Dehydrocostus lactone
CAS No.: 477-43-0
Chemical Name: Dehydrocostus lactone
Synonyms: EPILIGULYL OXIDE;DEHYDROCOSTUNOLIDE;ehydrocostuslactone;DEHYDROCOSTUSLACTONE;dehydrocostiolactone;Costus lactone, dehydro-;Dehydrocostus lactone-RM;DEHYDROCOSTUS LACTONE hplc;Dehydrocostus lactone, >=98%;Dehydrocostuslactone Standard
CBNumber: CB7106297
Molecular Formula: C15H18O2
Formula Weight: 230.3
MOL File: 477-43-0.mol

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Dehydrocostus lactone Property

Melting point:: 57.0 to 61.0 °C
Boiling point:: 140-143 °C(Press: 0.5 Torr)
Density: 1.09
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
form: Solid
color: White to Off-White
Odor: nutty
optical activity: [α]/D -14.0±3.0°, c = 1 in chloroform
λmax: 206nm(MeOH)(lit.)
InChIKey: NETSQGRTUNRXEO-XUXIUFHCSA-N
LogP: 1.480 (est)
CAS DataBase Reference: 477-43-0(CAS DataBase Reference)

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Safety

Safety Statements: 24/25
HS Code: 29322090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 42575
Product name: Dehydrocostus lactone
Purity: analytical standard
Packaging: 10mg
Price: $105
Updated: 2024/03/01

TCI Chemical

Product number: D5366
Product name: Dehydrocostus Lactone
Purity: >98.0%(GC)
Packaging: 10mg
Price: $81
Updated: 2024/03/01

TCI Chemical

Product number: D5366
Product name: Dehydrocostus Lactone
Purity: >98.0%(GC)
Packaging: 50mg
Price: $250
Updated: 2024/03/01

Cayman Chemical

Product number: 18485
Product name: Dehydrocostus lactone
Purity: ≥95%
Packaging: 5mg
Price: $54
Updated: 2024/03/01

Cayman Chemical

Product number: 18485
Product name: Dehydrocostus lactone
Purity: ≥95%
Packaging: 10mg
Price: $78
Updated: 2024/03/01

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Dehydrocostus lactone Chemical Properties,Usage,Production

Description

Dehydrocostus lactone is a natural sesquiterpene first isolated from costus root, which is used in traditional medicine. Dehydrocostus lactone has diverse anti-cancer properties in cells and animal models, causing cell cycle arrest, inducing apoptosis, diminishing multidrug resistance, and suppressing angiogenesis in cancer cells. It also has anti-inflammatory actions in cells, including the inhibition of signaling through STAT1 and STAT3.

Description

A guaianolide sesquiterpene lactone extracted from costus oil. Dehydrocostuslactone is one of the components of lactone-mix, with costunolide and alantolactone, used to detect Compositae-sensitive patients.

Uses

Dehydrocostus lactone is the oil extracted from Saussurea lappa is used in perfumery and in the Orient for all kinds of diseases.

Uses

Dehydrocostus Lactone is a compound known to be a growth regulator in plants. Known to affect cell viability and cell cycle distribution it may be useful in the application towards drug-resistant tumors.

Definition

ChEBI: An organic heterotricyclic compound and guaianolide sesquiterpene lactone that is acrylic acid which is substituted at position 2 by a 4-hydroxy-3,8-bis(methylene)decahydoazulen-5-yl group and in which the hydroxy group and the carboxy group have undergone formal condensation to afford the corresponding gamma-lactone.

Contact allergens

A guaianolide sesquiterpene lactone extracted from costus oil. It is one of the components of Lactone mix, with costunolide and alantolactone, used to detect Compositae-sensitive patients.

Dehydrocostus lactone Preparation Products And Raw materials

Raw materials

Preparation Products

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Dehydrocostus lactone Suppliers

Americas 1 China 202 Europe 1 Germany 1 India 3 Japan 2 United Kingdom 5 United States 26 Global 241

Carbosynth

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Country: United Kingdom
ProdList: 6005
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Apin Chemicals Limited (UK)

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ProdList: 6184
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MOLEKULA Ltd.

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ETA SCIENTIFIC Co.,Ltd

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Email: sales@etascientific.com
Country: United Kingdom
ProdList: 6090
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Apin Chemicals Ltd.

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Country: United Kingdom
ProdList: 6807
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View Lastest Price from Dehydrocostus lactone manufacturers

Chongqing Zhihe Biopharmaceutical Co., Ltd.

Product: Dehydrocostus lactone 477-43-0
Price: US $0.00-0.00/kg
Min. Order: 0.10000000149011612kg
Purity: ≥98%
Supply Ability: 20tons
Release date: 2024-01-04

Hebei Chuanghai Biotechnology Co,.LTD

Product: Dehydrocostus Lactone 477-43-0
Price: US $11.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-08-21

Shaanxi Dideu Medichem Co. Ltd

Product: Dehydrocostus lactone 477-43-0
Price: US $30.00-20.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200000KG
Release date: 2024-08-06

477-43-0, Dehydrocostus lactoneRelated Search:

4,4'-Diphenylmethane diisocyanate Tricine Tris(hydroxymethyl)aminomethane Methylene Blue Furan D-(+)-Glucono-1,5-lactone Spironolactone Costunolide Dehydrocostuslactone CYANIDIN CHLORIDE TRIOXSALEN Costuslactone Methylene Chloride Dehydrocostus lactone DEHYDROCOSTUSLACTONE(RG) Dehydrocostuslactone std. Dihydrodehydrocostus lactone

EPILIGULYL OXIDE

DEHYDROCOSTUSLACTONE

DEHYDROCOSTUS LACTONE hplc

(3aS,6aR,9aR,9bS)-Decahydro-3,6,9-tris(methylene)azuleno[4,5-b]furan-2(3H)-one

DEHYDROCOSTUNOLIDE

Azuleno[4,5-b]furan-2(3H)-one,decahydro-3,6,9-

Costus lactone, dehydro-

tris(methylene)-,(3aS,6aR,9aR,9bS)-

(3aS)-3,6,9-Tris(methylene)-2,3,3a,4,5,6,6aβ,7,8,9,9aβ,9bα-dodecahydroazuleno[4,5-b]furan-2-one

(3aS,6aβ,9aβ,9bα)-Dodecahydro-3,6,9-tris(methylene)azuleno[4,5-b]furan-2-one

3aβ,4,5,6,6aβ,7,8,9,9aβ,9bα-Decahydro-3,6,9-trismethyleneazuleno[4,5-b]furan-2(3H)-one

(3aS,6aR,9aR,9bS)-3,6,9-trimethylene-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[4,5-b]furan-2-one

(3aS,6aR,9aR,9bS)-3,6,9-trimethylidene-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[4,5-b]furan-2-one

Dehydrocostus Lactone 477-43-0

[3aS-(3aalpha,6aalpha,9aalpha,9bbeta)]-Decahydro-3,6,9-tris(methylene)-azuleno[4,5-b]furan-2(3H)-one

Dehydro-costus lactone (6CI,7CI)

Guaia-4(15),10(14),11(13)-trien-12-oic acid, 6alpha-hydroxy-, gamma-lactone

Dehydrocostus lactone, >=98%

Dehydrocostuslactone, 98%, from Common Vladimiria Root

Dehydrocostus Lactone ((-)-Dehydrocostus lactone

Dehydrocostuslactone Standard

Azuleno[4,5-b]furan-2(3H)-one, decahydro-3,6,9-tris(methylene)-, (3aS,6aR,9aR,9bS)-

ehydrocostuslactone

(3aS,6aR,9aR,9bS)-3,6,9-Trimethylenedecahydroazuleno[4,5-b]furan-2(9bH)-one

(3aS,6aR,9aR,9bS)-3,6,9-Trimethylenedecahydroazuleno[4,5-b]furan-2(3H)-one

dehydrocostiolactone

Dehydrocostus lactone-RM

477-43-0

447-43-0

C15H18O2

Sesquiterpenoids

Inhibitors

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

Heterocycles