(Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)ethenyl)-(1H)-1,2,4-triazolehydrochloride

Product Name: (Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)ethenyl)-(1H)-1,2,4-triazolehydrochloride
CAS No.: 117857-45-1
Chemical Name: (Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)ethenyl)-(1H)-1,2,4-triazolehydrochloride
Synonyms: R-72063;Loreclezole;LoreclezoleHCl;Loreclezole, 10 mM in DMSO;1-[(Z)-2-chloro-2-(2,4-dichlorophenyl)ethenyl]-1,2,4-triazole;(Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)vinyl)-1H-1,2,4-triazole;1-[(Z)-2-Chloro-2-(2,4-dichlorophenyl)ethenyl]-1H-1,2,4-triazole;1H-1,2,4-Triazole, 1-[(1Z)-2-chloro-2-(2,4-dichlorophenyl)ethenyl]-;(Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)vinyl)-1H-1,2,4-triazole hydrochloride;γ-Aminobutyric acid Receptor,R 72063,Inhibitor,GABA Receptor,Loreclezole,Gamma-aminobutyric acid Receptor,R72063,R-72063,inhibit
CBNumber: CB71075257
Molecular Formula: C10H6Cl3N3
Formula Weight: 274.53
MOL File: 117857-45-1.mol

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(Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)ethenyl)-(1H)-1,2,4-triazolehydrochloride Property

storage temp.: Inert atmosphere,2-8°C
solubility: <1.37mg/ml in DMSO; <1.37mg/ml in ethanol
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0025565
Product name: Loreclezole
Purity: 99.81%
Packaging: 5mg
Price: $120
Updated: 2021/12/16

ChemScene

Product number: CS-0025565
Product name: Loreclezole
Purity: 99.81%
Packaging: 10mg
Price: $180
Updated: 2021/12/16

ApexBio Technology

Product number: B6676
Product name: Loreclezolehydrochloride
Packaging: 5mg
Price: $189
Updated: 2021/12/16

ApexBio Technology

Product number: B6676
Product name: Loreclezolehydrochloride
Packaging: 10mg
Price: $284
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: BRS0009234
Product name: LORECLEZOLE
Purity: 95.00%
Packaging: 5MG
Price: $459.21
Updated: 2021/12/16

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(Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)ethenyl)-(1H)-1,2,4-triazolehydrochloride Chemical Properties,Usage,Production

Uses

Anti-epileptic.

Definition

ChEBI: 1-[2-chloro-2-(2,4-dichlorophenyl)ethenyl]-1,2,4-triazole is a dichlorobenzene.

Biological Activity

Subtype-selective GABA A receptor modulator. Acts as a positive allosteric modulator of β 2 or β 3-subunit containing receptors. Also acts as a negative modulator at a novel regulatory site, enhancing GABA A receptor sensitization. Inhibits homomeric ρ 1 GABA C receptors.

(Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)ethenyl)-(1H)-1,2,4-triazolehydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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(Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)ethenyl)-(1H)-1,2,4-triazolehydrochloride Suppliers

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117857-45-1, (Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)ethenyl)-(1H)-1,2,4-triazolehydrochlorideRelated Search:

Mefentrifluconazole (Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)ethenyl)-(1H)-1,2,4-triazolehydrochloride 2,4-Dichlorobenzyl chloride 2-Chlorobenzyl chloride 4-Chlorobenzyl chloride

LoreclezoleHCl

Loreclezole

1-[(Z)-2-chloro-2-(2,4-dichlorophenyl)ethenyl]-1,2,4-triazole

1-[(Z)-2-Chloro-2-(2,4-dichlorophenyl)ethenyl]-1H-1,2,4-triazole

R-72063

(Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)vinyl)-1H-1,2,4-triazole hydrochloride

1H-1,2,4-Triazole, 1-[(1Z)-2-chloro-2-(2,4-dichlorophenyl)ethenyl]-

γ-Aminobutyric acid Receptor,R 72063,Inhibitor,GABA Receptor,Loreclezole,Gamma-aminobutyric acid Receptor,R72063,R-72063,inhibit

(Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)vinyl)-1H-1,2,4-triazole

Loreclezole, 10 mM in DMSO

117857-45-1

C10H6Cl3N3HCl

C10H6Cl3N3

GABA/Glycine receptor