ChemicalBook > CAS DataBase List > (Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)ethenyl)-(1H)-1,2,4-triazolehydrochloride

(Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)ethenyl)-(1H)-1,2,4-triazolehydrochloride

Product Name
(Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)ethenyl)-(1H)-1,2,4-triazolehydrochloride
CAS No.
117857-45-1
Chemical Name
(Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)ethenyl)-(1H)-1,2,4-triazolehydrochloride
Synonyms
R-72063;Loreclezole;LoreclezoleHCl;1-[(Z)-2-chloro-2-(2,4-dichlorophenyl)ethenyl]-1,2,4-triazole;(Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)vinyl)-1H-1,2,4-triazole;1-[(Z)-2-Chloro-2-(2,4-dichlorophenyl)ethenyl]-1H-1,2,4-triazole;1H-1,2,4-Triazole, 1-[(1Z)-2-chloro-2-(2,4-dichlorophenyl)ethenyl]-;(Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)vinyl)-1H-1,2,4-triazole hydrochloride;γ-Aminobutyric acid Receptor,R 72063,Inhibitor,GABA Receptor,Loreclezole,Gamma-aminobutyric acid Receptor,R72063,R-72063,inhibit
CBNumber
CB71075257
Molecular Formula
C10H6Cl3N3
Formula Weight
274.53
MOL File
117857-45-1.mol
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(Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)ethenyl)-(1H)-1,2,4-triazolehydrochloride Property

storage temp. 
Inert atmosphere,2-8°C
solubility 
<1.37mg/ml in DMSO; <1.37mg/ml in ethanol
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0025565
Product name
Loreclezole
Purity
99.81%
Packaging
5mg
Price
$120
Updated
2021/12/16
ChemScene
Product number
CS-0025565
Product name
Loreclezole
Purity
99.81%
Packaging
10mg
Price
$180
Updated
2021/12/16
ApexBio Technology
Product number
B6676
Product name
Loreclezolehydrochloride
Packaging
5mg
Price
$189
Updated
2021/12/16
ApexBio Technology
Product number
B6676
Product name
Loreclezolehydrochloride
Packaging
10mg
Price
$284
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
BRS0009234
Product name
LORECLEZOLE
Purity
95.00%
Packaging
5MG
Price
$459.21
Updated
2021/12/16
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(Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)ethenyl)-(1H)-1,2,4-triazolehydrochloride Chemical Properties,Usage,Production

Uses

Anti-epileptic.

Definition

ChEBI: 1-[2-chloro-2-(2,4-dichlorophenyl)ethenyl]-1,2,4-triazole is a dichlorobenzene.

Biological Activity

Subtype-selective GABA A receptor modulator. Acts as a positive allosteric modulator of β 2 or β 3-subunit containing receptors. Also acts as a negative modulator at a novel regulatory site, enhancing GABA A receptor sensitization. Inhibits homomeric ρ 1 GABA C receptors.

(Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)ethenyl)-(1H)-1,2,4-triazolehydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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(Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)ethenyl)-(1H)-1,2,4-triazolehydrochloride Suppliers

Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71

117857-45-1, (Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)ethenyl)-(1H)-1,2,4-triazolehydrochlorideRelated Search:


  • LoreclezoleHCl
  • Loreclezole
  • 1-[(Z)-2-chloro-2-(2,4-dichlorophenyl)ethenyl]-1,2,4-triazole
  • 1-[(Z)-2-Chloro-2-(2,4-dichlorophenyl)ethenyl]-1H-1,2,4-triazole
  • R-72063
  • (Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)vinyl)-1H-1,2,4-triazole hydrochloride
  • 1H-1,2,4-Triazole, 1-[(1Z)-2-chloro-2-(2,4-dichlorophenyl)ethenyl]-
  • γ-Aminobutyric acid Receptor,R 72063,Inhibitor,GABA Receptor,Loreclezole,Gamma-aminobutyric acid Receptor,R72063,R-72063,inhibit
  • (Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)vinyl)-1H-1,2,4-triazole
  • 117857-45-1
  • C10H6Cl3N3HCl
  • C10H6Cl3N3
  • GABA/Glycine receptor