N-Boc-L-homoserine Methyl Ester
- Product Name
- N-Boc-L-homoserine Methyl Ester
- CAS No.
- 120042-11-7
- Chemical Name
- N-Boc-L-homoserine Methyl Ester
- Synonyms
- Boc-L-HomoSer-OMe;N-FmocL-homoserinemethylester;Boc-L-Homoserine methyl ester;N-Boc-L-homoserine Methyl Ester;methyl ((benzyloxy)carbonyl)-L-homoserinate;methyl (tert-butoxycarbonyl)-L-homoserinate;N-[(1,1-Dimethylethoxy)carbonyl]-L-homoserine Methyl Ester;tert-butyl (S)-1-(methoxycarbonyl)-3-hydroxypropylcarbamate;L-Homoserine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester;methyl (2S)-2-{[(tert-butoxy)carbonyl]amino}-4-hydroxybutanoate
- CBNumber
- CB71176561
- Molecular Formula
- C10H19NO5
- Formula Weight
- 233.26
- MOL File
- 120042-11-7.mol
N-Boc-L-homoserine Methyl Ester Property
- Boiling point:
- 364.6±37.0 °C(Predicted)
- Density
- 1.125±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- pka
- 10.91±0.46(Predicted)
- Appearance
- Colorless to light yellow Viscous Liquid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B600370
- Product name
- N-Boc-L-homoserineMethylEster
- Packaging
- 100mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- 3476AA
- Product name
- (S)-Methyl2-((tert-butoxycarbonyl)amino)-4-hydroxybutanoate
- Packaging
- 1g
- Price
- $317
- Updated
- 2021/12/16
- Product number
- AAA0000162
- Product name
- (S)-N-BOC-L-HOMOSERINE METHYL ESTER
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.78
- Updated
- 2021/12/16
- Product number
- AAA0000162
- Product name
- (S)-N-BOC-L-HOMOSERINE METHYL ESTER
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $580
- Updated
- 2021/12/16
- Product number
- 3476AA
- Product name
- (S)-Methyl2-((tert-butoxycarbonyl)amino)-4-hydroxybutanoate
- Packaging
- 5g
- Price
- $984
- Updated
- 2021/12/16
N-Boc-L-homoserine Methyl Ester Chemical Properties,Usage,Production
Synthesis
41088-86-2
74-88-4
120042-11-7
To a solution of (S)-2-(tert-butoxycarbonylamino)-4-hydroxybutyric acid 206 (8.5 g, 38 mmol) in DMF (50 mL) was added K2CO3 (5.24 g, 38 mmol) and iodomethane (5.4 g, 38 mmol). The reaction mixture was stirred at room temperature overnight. After the reaction was completed, the reaction mixture was diluted with water (500 mL) and extracted with dichloromethane (500 mL). The organic layers were combined, dried over anhydrous Na2SO4, filtered, and concentrated under reduced pressure to remove the solvent to afford the crude product (S)-2-((tert-butoxycarbonyl)amino)-4-hydroxybutyric acid methyl ester 207 (8.5 g, 90% yield).
References
[1] Patent: WO2017/189866, 2017, A1. Location in patent: Paragraph 0243
[2] Patent: WO2017/156074, 2017, A1. Location in patent: Paragraph 00494
[3] Biochemistry, 2017, vol. 56, # 8, p. 1062 - 1074
[4] Patent: WO2016/112088, 2016, A1. Location in patent: Paragraph 0481
N-Boc-L-homoserine Methyl Ester Preparation Products And Raw materials
Raw materials
Preparation Products
N-Boc-L-homoserine Methyl Ester Suppliers
- Tel
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- info@trc-canada.com
- Country
- Canada
- ProdList
- 6038
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