ChemicalBook > CAS DataBase List > N-Desmethyl Tamoxifen Hydrochloride

N-Desmethyl Tamoxifen Hydrochloride

Product Name
N-Desmethyl Tamoxifen Hydrochloride
CAS No.
15917-65-4
Chemical Name
N-Desmethyl Tamoxifen Hydrochloride
Synonyms
Nsc372964;Tamoxifen EP Impurity F HCl; N-Demethyltamoxifen Hydrochlorid;2-[4-[(Z)-1,2-Diphenylbut-1-enyl]ph;Tamoxifen Citrate EP Impurity F HCl;Tamoxifen Citrate Impurity F as Hydrochloride;Tamoxifen Citrate EP Impurity F as Hydrochloride;(Z)-2-(p-(1,2-Diphenyl-1-butenyl)phenoxy)-N-methylethylamine;Tamoxifen Citrate Impurity 6（Tamoxifen Citrate EP Impurity F);Tamoxifen Citrate Impurity 6（Tamoxifen Citrate EP Impurity F HCl)
CBNumber
CB71176581
Molecular Formula
C25H27NO.ClH
Formula Weight
393.955
MOL File
15917-65-4.mol
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N-Desmethyl Tamoxifen Hydrochloride Property

Melting point:
225-227°C
storage temp. 
room temp
solubility 
DMSO: ≥20mg/mL
form 
solid
Stability:
Light sensitive
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Safety

Hazard Codes 
T,N
Risk Statements 
45-46-60-50/53
Safety Statements 
53-45-60-61
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H350May cause cancer

H360May damage fertility or the unborn child

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P391Collect spillage. Hazardous to the aquatic environment

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D9069
Product name
N-Desmethyltamoxifen HCl
Purity
≥98% (HPLC), solid
Packaging
5mg
Price
$281
Updated
2024/03/01
TRC
Product number
D293900
Product name
N-DesmethylTamoxifenHydrochloride
Packaging
50mg
Price
$1390
Updated
2021/12/16
ChemScene
Product number
CS-0112190
Product name
N-Desmethyltamoxifenhydrochloride
Purity
99.62%
Packaging
100mg
Price
$1650
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
9028
Product name
N-Desmethyltamoxifen HCl
Packaging
25mg
Price
$1960
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0000705
Product name
N-DESMETHYL TAMOXIFEN HYDROCHLORIDE
Purity
95.00%
Packaging
50MG
Price
$1986.3
Updated
2021/12/16
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N-Desmethyl Tamoxifen Hydrochloride Chemical Properties,Usage,Production

Chemical Properties

White Crystalline Solid

Uses

A main metabolite of the anti-cancer drug Tamoxifen (T006000).

Uses

N-Desmethyltamoxifen HCl has been used as an internal standard in high-performance liquid chromatography (HPLC) for the quantification of metabolites from NG2 cell-derived astrocytes.

Biochem/physiol Actions

N-Desmethyltamoxifen HCl is the primary metabolite of tamoxifen. N-Desmethyltamoxifen HCl is an estrogen response modifer and protein kinase C inhibitor.

N-Desmethyl Tamoxifen Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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15917-65-4, N-Desmethyl Tamoxifen HydrochlorideRelated Search:

N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture) Tamoxifen Impurity 3 4-Benzyloxy β-Hydroxy TaMoxifen TaMoxifen DiMer 1-(4-(2-Dimethylamino)-2-ethoxyphenyl butanone N-Desmethyl-4-hydroxy Tamoxifen β-D-Glucuronide (E/Z Mixture) 4Hydroxy Tamoxifen Tamoxifen EP Impurity D (E)-4-Alloxycarboxyl Tamoxifen Endoxifen desdimethyltamoxifen TAMOXIFEN-N-OXIDE Droloxifene (E)-4-Acetoxy Tamoxifen N-Desmethyl Tamoxifen Methanethiosulfonate 2-[4-[(E)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethyl-ethanamine alpha-[4-[2-(dimethylamino)ethoxy]phenyl]-beta-ethyl-alpha-phenylphenethyl alcohol (E)-4-Hydroxy-N-desmethyl Tamoxifen

  • N-Demethyltamoxifen Hydrochlorid
  • (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N-methylethanamine Hydrochloride
  • Nsc372964
  • 2-[4-[(1Z)-1,2-Diphenyl-1-butenyl]phenoxy]-N-methylethanamine hydrochloride
  • (Z)-2-(p-(1,2-Diphenyl-1-butenyl)phenoxy)-N-methylethylamine
  • Tamoxifen Citrate EP Impurity F HCl
  • 2-[4-[(Z)-1,2-Diphenylbut-1-enyl]ph
  • Tamoxifen EP Impurity F HCl
  • Tamoxifen Citrate Impurity 6（Tamoxifen Citrate EP Impurity F HCl)
  • Tamoxifen Citrate Impurity 6（Tamoxifen Citrate EP Impurity F)
  • (Z)-2-(4-(1,2-Diphenylbut-1-en-1-yl)phenoxy)-N-methylethanamine hydrochloride
  • 2-[4-[(Z)-1,2-Diphenylbut-1-enyl]phenoxy]-N-methylethanamine Hydrochloride
  • PKC,sphingosine,inhibit,N-Desmethyltamoxifen,NDesmethyltamoxifen hydrochloride,cells,Protein kinase C,Inhibitor,phosphorylation,metabolism,Estrogen Receptor/ERR,carcinoma,AML,Drug Metabolite,ceramide,N Desmethyltamoxifen hydrochloride,Endogenous Metabolite,metabolite,antiestrogen
  • Tamoxifen Citrate EP Impurity F as Hydrochloride
  • Tamoxifen Citrate Impurity F as Hydrochloride
  • 15917-65-4
  • C25H28ClNO
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
  • Various Metabolites and Impurities