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TRIPELENNAMINE HYDROCHLORIDE

Product Name
TRIPELENNAMINE HYDROCHLORIDE
CAS No.
154-69-8
Chemical Name
TRIPELENNAMINE HYDROCHLORIDE
Synonyms
Azaron;TRIPELENNAMINE HCL;ReCovr;dehistin;piristin;Ahistamin;pyrinamine;stanzamine;tri-tumine;pyrabenzamine
CBNumber
CB7126697
Molecular Formula
C16H22ClN3
Formula Weight
291.82
MOL File
154-69-8.mol
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TRIPELENNAMINE HYDROCHLORIDE Property

Melting point:
192-193℃
Density 
1.20
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO : 25 mg/mL (85.67 mM; Need ultrasonic)
form 
Solid
color 
White to off-white
EPA Substance Registry System
Tripelennamine hydrochloride (154-69-8)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
US3150000
HS Code 
2933399090
Toxicity
LD50 in mice (mg/kg): 47 i.p. (Walker)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
R288918
Product name
TRIPELENNAMINE HYDROCHLORIDE
Purity
Aldrich
Packaging
1g
Price
$179
Updated
2024/03/01
Sigma-Aldrich
Product number
PHR3258
Product name
Tripelennamine Hydrochloride
Purity
certified reference material, pharmaceutical secondary standard
Packaging
500MG
Price
$173
Updated
2024/03/01
Sigma-Aldrich
Product number
1695004
Product name
TRIPELENNAMINE HYDROCHLORIDE
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200mg
Price
$164.8
Updated
2024/03/01
Sigma-Aldrich
Product number
T7511
Product name
Tripelennamine hydrochloride
Purity
analytical standard
Packaging
25g
Price
$77.1
Updated
2024/03/01
TRC
Product number
T808325
Product name
Tripelennamine hydrochloride
Packaging
1g
Price
$90
Updated
2021/12/16
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TRIPELENNAMINE HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Tripelennamine is a first-generation antihistamine, used in the treatment of asthma, hay fever, and urticaria.

Uses

antihistaminic;histamine H1 antagonist

brand name

PBZ (Novartis).

General Description

Tripelennamine hydrochlorideis a white crystalline powder that darkensslowly on exposure to light. The salt is soluble in water(1:0.77) and in alcohol (1:6). It has a pKa of about 9, and a0.1% solution has a pH of about 5.5.
Tripelennamine, the first ethylenediamine developed inthe United States and is well absorbed when given orally. Itappears to be as effective as diphenhydramine and may havethe advantage of fewer and less severe side reactions.Drowsiness may occur, however, and may impair the abilityto perform tasks requiring alertness. The concurrent use ofalcoholic beverages should be avoided.

General Description

Odorless white crystalline powder or solid. Bitter taste. Solutions are neutral to litmus. pH of aqueous solution (25 mg/mL): 6.71. pH of aqueous solution (50 mg/mL): 6.67. pH of aqueous solution (100 mg/mL): 5.56.

Air & Water Reactions

Water soluble.

Reactivity Profile

TRIPELENNAMINE HYDROCHLORIDE behaves as a weak organic acid. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible.

Fire Hazard

Flash point data for TRIPELENNAMINE HYDROCHLORIDE are not available; however, TRIPELENNAMINE HYDROCHLORIDE is probably combustible.

Veterinary Drugs and Treatments

Antihistamines are used in veterinary medicine to reduce or help prevent histamine mediated adverse effects. Tripelennamine has been used as a CNS stimulant in “Downer cows” when administered slow IV.

TRIPELENNAMINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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TRIPELENNAMINE HYDROCHLORIDE Suppliers

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View Lastest Price from TRIPELENNAMINE HYDROCHLORIDE manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
TripelennaMine Hydrochloride 154-69-8
Price
US $0.00/Kg/Bag
Min. Order
100g
Purity
98%-102%;USP
Supply Ability
1000G
Release date
2021-07-22
Shaanxi Dideu Medichem Co. Ltd
Product
TripelennaMine Hydrochloride 154-69-8
Price
US $1.00-1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
50tons
Release date
2020-05-08
Hong Kong Tiansheng New Material Trading Co., Ltd
Product
Tripelennamine (hydrochloride) 154-69-8
Price
US $2.20/KG
Min. Order
100g
Purity
99%
Supply Ability
6kg
Release date
2021-12-09

154-69-8, TRIPELENNAMINE HYDROCHLORIDERelated Search:

Daunorubicin hydrochloride Trimetazidine dihydrochloride DL-NORADRENALINE HYDROCHLORIDE Fenasi Dyclonine hydrochloride Tamsulosin Benzhexol hydrochloride Diphenhydramine Hydrochloride Ambroxol hydrochloride Tripelennamine TRIPELENNAMINE HYDROCHLORIDE Chloropyramine hydrochloride Chloropyramine TRIPELENNAMINE HYDROCHLORIDE,PYRIBENZAMINE HCL N-(4-methoxybenzyl-N',N'-dimethyl-N-2-pyridylethylenediamine monohydrochloride 4-IODO-N-[2-[4-(METHOXYPHENYL)-1-PIPERAZINYL]ETHYL]-N-2-PYRIDINYL-BENZAMIDE HYDROCHLORIDE Mirtazapine-d4 HCl 4-FLUORO-N-(2-[4-(2-METHOXYPHENYL)1-PIPERAZINYL]ETHYL)-N-(2-PYRIDINYL)BENZAMIDE DIHYDROCHLORIDE

  • 2-(benzyl(2-(dimethylamino)ethyl)amino)-pyridinmonohydrochloride
  • 2-ethanediamine,n,n-dimethyl-n’-(phenylmethyl)-n’-2-pyridinyl-monohydroc
  • 2-(benzyl(2-(dimethylamino)ethyl)amino)pyridinemonohydrochloride
  • 2-(benzyl(2-(dimethylamino)ethyl)amino)-pyridinhydrochloride
  • 1,2-Ethanediamine, N,N-dimethyl-N'-(phenylmethyl)-N'-2-pyridinyl-, monohydrochloride
  • Ahistamin
  • Antiallergicum medivet
  • Ethylenediamine, N-benzyl-N',N'-dimethyl-N-(2-pyridyl)-, hydrochloride
  • N(Sup 1)-.alpha.-pyridyl-N(sup 1)-benzyl-N,N-dimethyl ethylenediamine monohydrochloride
  • N1,N1-Dimethyl-N2-(phenylmethyl)-N2-(2-pyridinyl)-1,2-ethanediamine hydrochloride
  • ReCovr
  • Tripelennamine Hydrochloride (200 mg)
  • Azaron
  • N-Benzyl-N',N'-diMethyl-N-2-pyridylethylen
  • TRIPELENNAMINE HYDROCHLORIDE TABLETS
  • TripelennaMine HCI
  • N-benzyl-N-(2-(dimethylamino)ethyl)pyridin-2-amine hydrochloride
  • N1-Benzyl-N2,N2-dimethyl-N1-(pyridin-2-yl)ethane-1,2-diamine hydrochloride
  • dehistin
  • dehistinmonohydrochloride
  • n(sup1)-alpha-pyridyl-n(sup1)-benzyl-n,n-dimethylethylenediaminemonohydro
  • n,n-dimethyl-n’-(2-pyridyl)-n’-benzylethylenediaminehydrochloride
  • n-benzyl-n’,n’-dimethyl-n-(2-pyridyl)-ethylenediaminhydrochloride
  • n-benzyl-n’,n’-dimethyl-n-2-pyridyl-ethylenediaminehydrochloride
  • n-benzyl-n-alpha-pyridyl-n’,n’-dimethyl-aethylendiamin-hydrochlorid
  • n-benzyl-n-dimethylaminoethylalpha-aminopyridinehydrochloride
  • piristin
  • pyrabenzamine
  • pyribenzaminehydrochloride
  • pyribenzaminemonohydrochloride
  • pyrinamine
  • stanzamine
  • tripelenaminehydrochloride
  • tripelennaminemonohydrochloride
  • tri-tumine
  • PYRIBENZAMINE HCL
  • 2-(benzyl[2-dimethylaminoethyl]amino)pyridine
  • TRIPELENNAMINEHYDROCHLORIDE,USP
  • PYRIDINE,2-(BENZYL(2-(DIMETHYLAMINO)ETHYL)AMINO)-,MONOHYDROCHLORIDE
  • TRIPELENAMINEHCL
  • 2-(Benzyl[2-dimethylaminoethyl]amino)pyridine, N-Benzyl-Nμ,Nμ-dimethyl-N-(2-pyridyl)ethylenediamine hydrochloride
  • Tripelennanmine Hydrochloride
  • 2-[BENZYL(2-DIMETHYLAMINOETHYL)AMINO]PYRIDINE HYDROCHLORIDE
  • N-Benzyl-N',N'-dimethyl-N-pyridin-2-yl-ethane-1,2-diamine HYDROCHLORIDE
  • TRIPELENNAMINE HCL
  • TRIPELENNAMINE HYDROCHLORIDE
  • N,N-dimethyl-N'-(phenylmethyl)-N'-(2-pyridinyl)ethane-1,2-diamine hydrochloride
  • 1,2-Ethanediamine,N1,N1-dimethyl-N2-(phenylmethyl)-N2-2-pyridinyl-, hydrochloride (1:1)
  • Tripelennamine Hydrochloride Standard
  • Chloropyramine Impurity 1 HCl (Tripelennamine HCl, Pyribenzamine HCl)
  • Chloropyramine Impurity 1 HCl
  • TRIPELENNAMINE HYDROCHLORIDE USP/EP/BP
  • TIANFU 154-69-8 TRIPELENNAMINE HYDROCHLORIDE
  • Tripelennamine,Inhibitor,inhibit,antihistaminic,Tripelennamine hydrochloride,Histamine Receptor,rhinitis,allergic response,conjunctivitis,Endogenous Metabolite
  • BMS-986165 (Deucravacitinib) second-generation
  • Avanafil Impurity 103
  • Tripyridamole hydrochloride
  • Tripelennamine hydrochloride in methanol