ChemicalBook > CAS DataBase List > 2,3,5-Trifluoropyridine

2,3,5-Trifluoropyridine

Synthesis

Product Name: 2,3,5-Trifluoropyridine
CAS No.: 76469-41-5
Chemical Name: 2,3,5-Trifluoropyridine
Synonyms: 2,3,5-TRIFLUOROPYRIDINE;Pyridine, 2,3,5-trifluoro-;2,3,5-Trifluoropyridine98%;2,3,5-Trifluoropyridine 98%;2,3,5-Trifluoropyridine ISO 9001：2015 REACH
CBNumber: CB7130845
Molecular Formula: C5H2F3N
Formula Weight: 133.07
MOL File: 76469-41-5.mol

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2,3,5-Trifluoropyridine Property

Boiling point:: 102°C
Density: 1,499 g/cm³
refractive index: 1.422
Flash point:: 30°C
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: clear liquid
pka: -5.28±0.20(Predicted)
color: Colorless to Light yellow
Specific Gravity: 1.499
Water Solubility: Difficult to mix in water.
BRN: 6385503
InChI: InChI=1S/C5H2F3N/c6-3-1-4(7)5(8)9-2-3/h1-2H
InChIKey: JKVOXNTXYMXDHN-UHFFFAOYSA-N
SMILES: C1(F)=NC=C(F)C=C1F
CAS DataBase Reference: 76469-41-5(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,F,C
Risk Statements: 36/37/38-10
Safety Statements: 26-36/37/39-37
RIDADR: 1993
Hazard Note: Flammable/Irritant
HazardClass: 3
PackingGroup: III
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical

Product number: T2778
Product name: 2,3,5-Trifluoropyridine
Purity: >98.0%(GC)
Packaging: 5g
Price: $84
Updated: 2025/07/31

TCI Chemical

Product number: T2778
Product name: 2,3,5-Trifluoropyridine
Purity: >98.0%(GC)
Packaging: 25g
Price: $283
Updated: 2025/07/31

TRC

Product number: B593208
Product name: 2,3,5-trifluoropyridine
Packaging: 1g
Price: $45
Updated: 2021/12/16

TRC

Product number: B593208
Product name: 2,3,5-trifluoropyridine
Packaging: 5g
Price: $155
Updated: 2021/12/16

Matrix Scientific

Product number: 009192
Product name: 2,3,5-Trifluoropyridine
Purity: 95%
Packaging: 25g
Price: $180
Updated: 2021/12/16

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2,3,5-Trifluoropyridine Chemical Properties,Usage,Production

Synthesis

A solution of pentafluoropyridine (3) (0.6 g, 3.6 mmol) in tetrahydrofuran (5 cm3) was added to a mixture of lithium aluminium hydride (5 cm3, 5 mmol of 1.0 M solution in ether) and 12-crown-4 (1.0 g, 5.7 mmol) in THF (10 cm3) at 0 "C, with stirring, under an atmosphere of dry nitrogen. The mixture was stirred at 0 "C for 10 min, then at room temperature for 19 h, then iced water added and the mixture extracted into ether. The ether solution was dried (MgS04), evaporated and the products were isolated by preparative scale GLC (1 0% SE, 40"C), giving 2,3,5-trifluoropyridine (7, 92%) 50(Found: C, 44.9; H, 1.3; N, 10.5. Calc. for C5H2F3N: C, 45.1; H, 1.5; N, 10.5); IR spectrum no. 2; mass spectrum no. 3; nmr spectrum no. 3.

Chemical Properties

Colorless liquid

Uses

It is employed as a pharmaceutical intermediate.

References

[1] Journal of Fluorine Chemistry, 2013, vol. 155, p. 132 - 142

2,3,5-Trifluoropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2,3,5-Trifluoropyridine manufacturers

Zouping mingyuan import & export trading co., ltd

Product: 2,3,5-Trifluoropyridine 76469-41-5
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 5 ton
Release date: 2025-08-05

Shaanxi Dideu Medichem Co. Ltd

Product: 2,3,5-Trifluoropyridine 76469-41-5
Price: US $21.00/KG
Min. Order: 1KG
Purity: 99.0% min
Supply Ability: 100 tons
Release date: 2021-04-29

Shaanxi Dideu Medichem Co. Ltd

Product: 2,3,5-Trifluoropyridine 76469-41-5
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-11-24

76469-41-5, 2,3,5-TrifluoropyridineRelated Search:

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2,3,5-TRIFLUOROPYRIDINE

2,3,5-Trifluoropyridine 98%

2,3,5-Trifluoropyridine98%

Pyridine, 2,3,5-trifluoro-

2,3,5-Trifluoropyridine ISO 9001：2015 REACH

76469-41-5

Fluorine series

Pyridine

bc0001