Synthesis
ChemicalBook > CAS DataBase List > 2,3,5-Trifluoropyridine

2,3,5-Trifluoropyridine

Synthesis
Product Name
2,3,5-Trifluoropyridine
CAS No.
76469-41-5
Chemical Name
2,3,5-Trifluoropyridine
Synonyms
2,3,5-TRIFLUOROPYRIDINE;Pyridine, 2,3,5-trifluoro-;2,3,5-Trifluoropyridine98%;2,3,5-Trifluoropyridine 98%;2,3,5-Trifluoropyridine ISO 9001：2015 REACH
CBNumber
CB7130845
Molecular Formula
C5H2F3N
Formula Weight
133.07
MOL File
76469-41-5.mol
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2,3,5-Trifluoropyridine Property

Boiling point:
102°C
Density 
1,499 g/cm3
refractive index 
1.422
Flash point:
30°C
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
clear liquid
pka
-5.28±0.20(Predicted)
color 
Colorless to Light yellow
Specific Gravity
1.499
Water Solubility 
Difficult to mix in water.
BRN 
6385503
CAS DataBase Reference
76469-41-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,F,C
Risk Statements 
36/37/38-10
Safety Statements 
26-36/37/39-37
RIDADR 
1993
Hazard Note 
Flammable/Irritant
HazardClass 
3
PackingGroup 
III
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical
Product number
T2778
Product name
2,3,5-Trifluoropyridine
Purity
>98.0%(GC)
Packaging
5g
Price
$84
Updated
2024/03/01
TCI Chemical
Product number
T2778
Product name
2,3,5-Trifluoropyridine
Purity
>98.0%(GC)
Packaging
25g
Price
$283
Updated
2024/03/01
Alfa Aesar
Product number
L19542
Product name
2,3,5-Trifluoropyridine, 98+%
Packaging
5g
Price
$96.1
Updated
2021/12/16
Alfa Aesar
Product number
L19542
Product name
2,3,5-Trifluoropyridine, 98+%
Packaging
1g
Price
$32.9
Updated
2021/12/16
TRC
Product number
B593208
Product name
2,3,5-trifluoropyridine
Packaging
1g
Price
$45
Updated
2021/12/16
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2,3,5-Trifluoropyridine Chemical Properties,Usage,Production

Synthesis

A solution of pentafluoropyridine (3) (0.6 g, 3.6 mmol) in tetrahydrofuran (5  cm3) was added to a mixture of lithium aluminium hydride (5 cm3, 5 mmol of 1.0 M  solution in ether) and 12-crown-4 (1.0 g, 5.7 mmol) in THF (10 cm3) at 0 "C, with  stirring, under an atmosphere of dry nitrogen. The mixture was stirred at 0 "C for 10  min, then at room temperature for 19 h, then iced water added and the mixture extracted  into ether. The ether solution was dried (MgS04), evaporated and the products were  isolated by preparative scale GLC (1 0% SE, 40"C), giving 2,3,5-trifluoropyridine (7,  92%) 50(Found: C, 44.9; H, 1.3; N, 10.5. Calc. for C5H2F3N: C, 45.1; H, 1.5; N,  10.5); IR spectrum no. 2; mass spectrum no. 3; nmr spectrum no. 3.

Chemical Properties

Colorless liquid

Uses

It is employed as a pharmaceutical intermediate.

2,3,5-Trifluoropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2,3,5-Trifluoropyridine manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2,3,5-Trifluoropyridine 76469-41-5
Price
US $21.00/KG
Min. Order
1KG
Purity
99.0% min
Supply Ability
100 tons
Release date
2021-04-29
Shaanxi Dideu Medichem Co. Ltd
Product
2,3,5-Trifluoropyridine 76469-41-5
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-11-24
Career Henan Chemical Co
Product
2,3,5-Trifluoropyridine 76469-41-5
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2020-01-10

76469-41-5, 2,3,5-TrifluoropyridineRelated Search:

3-Aminopyridine 2,4,6-Collidine 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one Pyridine sulfur trioxide 2,3,5,6-Tetrafluoropyridine 2,3,5,6-TETRAFLUORO-4-PYRIDINE-CARBONITRILE 4-AMINO-2,3,5,6-TETRAFLUOROPYRIDINE 4-(DIMETHYLAMINO)-2,3,5,6-TETRAFLUOROPYRIDINE 2 3 5 6-TETRAFLUORO-4-METHYLPYRIDINE 9& Pentafluoropyridine 2,3,5-TRIFLUOROPYRIDINE-4-CARBOXYLIC ACID 2,4,5-Trifluoropyridine 2-Amino-3-chloro-5-trifluoropyridine 2,4,6-Trifluoropyridine 98%,2,4,6-Trifluoropyridine98%,2,4,6-TRIFLUOROPYRIDINE 2,3,4-Trifluoropyridine 3,5-Dichloro-2,4,6-trifluoropyridine 2,3,6-TRIFLUOROPYRIDINE-4-CARBOXYLIC ACID 2,3,5-TRIFLUOROPYRIDINE-4-CARBOXYLIC ACID, 97,2,3,5-TRIFLUOROPYRIDINE-4-CARBOXYLIC AC&

  • 2,3,5-TRIFLUOROPYRIDINE
  • 2,3,5-Trifluoropyridine 98%
  • 2,3,5-Trifluoropyridine98%
  • Pyridine, 2,3,5-trifluoro-
  • 2,3,5-Trifluoropyridine ISO 9001：2015 REACH
  • 76469-41-5
  • Fluorine series
  • Pyridine
  • bc0001