protohypericin

Product Name: protohypericin
CAS No.: 548-03-8
Chemical Name: protohypericin
Synonyms: protohypericin;Protohypericin,naphthodianthrone,Inhibitor,NSCLC,inhibit;1,3,4,6,8,15-Hexahydroxy-10,13-dimethyldibenzo[a,o]perylene-7,16-dione;Dibenzo[a,o]perylene-7,16-dione, 1,3,4,6,8,15-hexahydroxy-10,13-dimethyl-
CBNumber: CB71321079
Molecular Formula: C30H18O8
Formula Weight: 506.46
MOL File: 548-03-8.mol

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protohypericin Property

Boiling point:: 954.3±65.0 °C(Predicted)
Density: 1.736±0.06 g/cm3(Predicted)
solubility: DMSO: Sparingly Soluble: 1-10 mg/ml
Methanol: Sparingly Soluble: 1-10 mg/ml
form: Solid
pka: 5.63±0.20(Predicted)
color: Purple to black
LogP: 8.870 (est)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FP157330
Product name: Protohypericin
Packaging: 2mg
Price: $150
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FP157330
Product name: Protohypericin
Packaging: 5mg
Price: $200
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FP157330
Product name: Protohypericin
Packaging: 10mg
Price: $350
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FP157330
Product name: Protohypericin
Packaging: 25mg
Price: $750
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0031944
Product name: PROTOHYPERICIN
Purity: 95.00%
Packaging: 5MG
Price: $990.99
Updated: 2021/12/16

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protohypericin Chemical Properties,Usage,Production

Uses

Protohypericin is a naturally occurring naphthodianthrone derived from plant Hypericum perforatum. Radioiodinated protohypericin is used in Tumor necrosis targeted radiotherapy[1][2].

References

[1] Baugh SF. Simultaneous determination of protopseudohypericin, pseudohypericin, protohypericin, and hypericin without light exposure. J AOAC Int. 2005 Nov-Dec;88(6):1607-12. PMID:16526439
[2] Liu X, et al. Tumor necrosis targeted radiotherapy of non-small cell lung cancer using radioiodinated protohypericin in a mouse model. Oncotarget. 2015 Sep 22;6(28):26400-10. DOI:10.18632/oncotarget.4568
[3] GEORGIOS PIPEROPOULOS . Determination of naphthodianthrones in plant extracts from Hypericum perforatum L. by liquid chromatography–electrospray mass spectrometry[J]. Journal of Chromatography B: Biomedical Sciences and Applications, 1997, 695 2: Pages 309-316. DOI: 10.1016/s0378-4347(97)00188-6
[4] E M DELAEY. Photocytotoxicity of protohypericin after photoconversion to hypericin.[J]. Planta medica, 1999, 65 8: 719-722. DOI: 10.1055/s-1999-14050

protohypericin Preparation Products And Raw materials

Raw materials

Preparation Products

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protohypericin Suppliers

China 78 United Kingdom 3 United States 4 Global 85

Chengdu Biopurify Phytochemicals Ltd.

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Wuhan ChemFaces Biochemical Co., Ltd.

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Lanzhou Angeli Biochemical Technology Co., Ltd.

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Chengdu Alfa Biotechnology Co.,Ltd.

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View Lastest Price from protohypericin manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Protohypericin 548-03-8
Price: US $0.00/mg
Min. Order: 20mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-05-22

Career Henan Chemical Co

Product: protohypericin 548-03-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%HPLC
Supply Ability: 10 tons
Release date: 2020-01-09

548-03-8, protohypericinRelated Search:

protopseudohypericin PROTOHYPERICIN Original Hypericin Standard HYPERFORIN Polysaccharide Hypericin Lotus Leaf Extract 1,3-DIHYDROXYNAPHTHALENE 2-HYDROXYANTHRACENE 1-HYDROXY-PHENANTHRENE Perylene Benz[a]anthracene 4-HYDROXY-PHENANTHRENE 2-methylbenz(a)anthracene BENZO(C)PHENANTHRENE 2-HYDROXY-PHENANTHRENE (5)HELICENE protohypericin BENZO(A)PERYLENE

protohypericin

1,3,4,6,8,15-Hexahydroxy-10,13-dimethyldibenzo[a,o]perylene-7,16-dione

Dibenzo[a,o]perylene-7,16-dione, 1,3,4,6,8,15-hexahydroxy-10,13-dimethyl-

Protohypericin,naphthodianthrone,Inhibitor,NSCLC,inhibit

548-03-8

Anthraquinones, Hydroquinones and Quinones