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protohypericin

Product Name
protohypericin
CAS No.
548-03-8
Chemical Name
protohypericin
Synonyms
protohypericin;Protohypericin,naphthodianthrone,Inhibitor,NSCLC,inhibit;1,3,4,6,8,15-Hexahydroxy-10,13-dimethyldibenzo[a,o]perylene-7,16-dione;Dibenzo[a,o]perylene-7,16-dione, 1,3,4,6,8,15-hexahydroxy-10,13-dimethyl-
CBNumber
CB71321079
Molecular Formula
C30H18O8
Formula Weight
506.46
MOL File
548-03-8.mol
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protohypericin Property

Boiling point:
954.3±65.0 °C(Predicted)
Density 
1.736±0.06 g/cm3(Predicted)
solubility 
DMSO: Sparingly Soluble: 1-10 mg/ml
Methanol: Sparingly Soluble: 1-10 mg/ml
form 
Solid
pka
5.63±0.20(Predicted)
color 
Purple to black
LogP
8.870 (est)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FP157330
Product name
Protohypericin
Packaging
2mg
Price
$150
Updated
2021/12/16
Biosynth Carbosynth
Product number
FP157330
Product name
Protohypericin
Packaging
5mg
Price
$200
Updated
2021/12/16
Biosynth Carbosynth
Product number
FP157330
Product name
Protohypericin
Packaging
10mg
Price
$350
Updated
2021/12/16
Biosynth Carbosynth
Product number
FP157330
Product name
Protohypericin
Packaging
25mg
Price
$750
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0031944
Product name
PROTOHYPERICIN
Purity
95.00%
Packaging
5MG
Price
$990.99
Updated
2021/12/16
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protohypericin Chemical Properties,Usage,Production

Uses

Protohypericin is a naturally occurring naphthodianthrone derived from plant Hypericum perforatum. Radioiodinated protohypericin is used in Tumor necrosis targeted radiotherapy[1][2].

References

[1] Baugh SF. Simultaneous determination of protopseudohypericin, pseudohypericin, protohypericin, and hypericin without light exposure. J AOAC Int. 2005 Nov-Dec;88(6):1607-12. PMID:16526439
[2] Liu X, et al. Tumor necrosis targeted radiotherapy of non-small cell lung cancer using radioiodinated protohypericin in a mouse model. Oncotarget. 2015 Sep 22;6(28):26400-10. DOI:10.18632/oncotarget.4568
[3] GEORGIOS PIPEROPOULOS . Determination of naphthodianthrones in plant extracts from Hypericum perforatum L. by liquid chromatography–electrospray mass spectrometry[J]. Journal of Chromatography B: Biomedical Sciences and Applications, 1997, 695 2: Pages 309-316. DOI: 10.1016/s0378-4347(97)00188-6
[4] E M DELAEY. Photocytotoxicity of protohypericin after photoconversion to hypericin.[J]. Planta medica, 1999, 65 8: 719-722. DOI: 10.1055/s-1999-14050

protohypericin Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from protohypericin manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Protohypericin 548-03-8
Price
US $0.00/mg
Min. Order
20mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-05-22
Career Henan Chemical Co
Product
protohypericin 548-03-8
Price
US $1.00/KG
Min. Order
1KG
Purity
98%HPLC
Supply Ability
10 tons
Release date
2020-01-09

548-03-8, protohypericinRelated Search:

protopseudohypericin PROTOHYPERICIN Original Hypericin Standard HYPERFORIN Polysaccharide Hypericin Lotus Leaf Extract 1,3-DIHYDROXYNAPHTHALENE 2-HYDROXYANTHRACENE 1-HYDROXY-PHENANTHRENE Perylene Benz[a]anthracene 4-HYDROXY-PHENANTHRENE 2-methylbenz(a)anthracene BENZO(C)PHENANTHRENE 2-HYDROXY-PHENANTHRENE (5)HELICENE protohypericin BENZO(A)PERYLENE

  • protohypericin
  • 1,3,4,6,8,15-Hexahydroxy-10,13-dimethyldibenzo[a,o]perylene-7,16-dione
  • Dibenzo[a,o]perylene-7,16-dione, 1,3,4,6,8,15-hexahydroxy-10,13-dimethyl-
  • Protohypericin,naphthodianthrone,Inhibitor,NSCLC,inhibit
  • 548-03-8
  • Anthraquinones, Hydroquinones and Quinones