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desmethylanethol trithione

Product Name
desmethylanethol trithione
CAS No.
18274-81-2
Chemical Name
desmethylanethol trithione
Synonyms
ACS 1;Adt-Oh;Anethole impurity 2;desmethylanethol trithione;Anethole Trithione impurity 2;5-(4-hydroxyphenyl)dithiole-3-thione;5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione;3H-1,2-Dithiole-3-thione, 5-(4-hydroxyphenyl)-
CBNumber
CB71347875
Molecular Formula
C9H6OS3
Formula Weight
226.34
MOL File
18274-81-2.mol
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desmethylanethol trithione Property

Melting point:
191-192 °C
Boiling point:
431.4±55.0 °C(Predicted)
Density 
1.56±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
DMF: 15 mg/ml; DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml; DMSO: 5 mg/ml; Ethanol: 1 mg/ml
form 
A crystalline solid
pka
9.78±0.30(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
17102
Product name
ADT-OH
Purity
≥98%
Packaging
5mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
17102
Product name
ADT-OH
Purity
≥98%
Packaging
10mg
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
17102
Product name
ADT-OH
Purity
≥98%
Packaging
50mg
Price
$230
Updated
2024/03/01
Cayman Chemical
Product number
17102
Product name
ADT-OH
Purity
≥98%
Packaging
100mg
Price
$396
Updated
2024/03/01
Matrix Scientific
Product number
121268
Product name
Desmethylanetholtrithione
Purity
97%
Packaging
1g
Price
$400
Updated
2021/12/16
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desmethylanethol trithione Chemical Properties,Usage,Production

Description

ADT-OH is a derivative of anethole dithiolethione (ADT) and synthetic hydrogen sulfide (H2S) donor. It can be readily esterified with other moieties. For example, it can be coupled with therapeutics like nonsteroidal anti-inflammatory drugs, as in the generation of ATB-343 . ADT-OH has also been linked with a mitochondria-targeting motif to produce AP-39 , which selectively increases mitochondrial H2S levels. ADT-OH is used both in cells and in animals for comparative studies with derived chimeras.

Uses

is used in method for preventing or treating diseases associated with administration of VEGFR and/or VEGF inhibitor.

desmethylanethol trithione Preparation Products And Raw materials

Raw materials

Preparation Products

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18274-81-2, desmethylanethol trithioneRelated Search:


  • desmethylanethol trithione
  • Adt-Oh
  • ACS 1
  • 5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione
  • Anethole impurity 2
  • 5-(4-hydroxyphenyl)dithiole-3-thione
  • Anethole Trithione impurity 2
  • 3H-1,2-Dithiole-3-thione, 5-(4-hydroxyphenyl)-
  • 18274-81-2
  • C9H6OS3